An integrative biology approach for analysis of drug action in models of human vascular inflammation

FASEB Journal

Volumn 18, Issue 11, 2004, Pages 1279-1281

  Kunkel, Eric J ^a   Dea, Marlene ^a   Ebens, Allen ^a   Hytopoulos, Evangelos ^a   Melrose, Jennifer ^a   Nguyen, Dat ^a   Ota, Ken S ^a   Plavec, Ivan ^a   Wang, Yuker ^a   Watson, Susan R ^a   Butcher, Eugene C ^b   Berg, Ellen L ^a  

^a BioSeek Inc   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; 5 (2 AMINO 4 PYRIMIDINYL) 4 (4 FLUOROPHENYL) 1 (4 PIPERIDINYL)IMIDAZOLE; 5 (2,2 DICYANOVINYL) 2 NITROPHENOL; CD14 ANTIGEN; CD31 ANTIGEN; CD40 ANTIGEN; CD69 ANTIGEN; COLONY STIMULATING FACTOR 1; CYCLOSPORIN A; DOCEBENONE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON; HLA DR ANTIGEN; IMMUNOSUPPRESSIVE AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MONOCYTE CHEMOTACTIC PROTEIN 1; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHODIESTERASE IV INHIBITOR; RAPAMYCIN; ROLIPRAM; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; TACROLIMUS; THROMBOPLASTIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ZM 39923;

ARTICLE; BIOLOGICALLY MULTIPLEXED ACTIVITY PROFILING; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG CLASSIFICATION; DRUG DETERMINATION; DRUG DEVELOPMENT; DRUG DISCRIMINATION; DRUG MECHANISM; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC SCREENING; HUMAN; HUMAN CELL; INFLAMMATION; PARAMETER; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRODUCIBILITY; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STRUCTURE ACTIVITY RELATION; TECHNIQUE; VALIDATION PROCESS; VASCULITIS;

ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LEUKOCYTES, MONONUCLEAR; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; RNA, SMALL INTERFERING; TRANSFECTION; UMBILICAL VEINS; VASCULITIS;

EID: 4644264129     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.04-1538fje     Document Type: Article

References (0)