CYP3A5 Contributes significantly to CYP3A-mediated drug oxidations in liver microsomes from Japanese subjects.

Drug metabolism and pharmacokinetics

Volumn 19, Issue 2, 2004, Pages 120-129

  Yamaori, Satoshi ^a   Yamazaki, Hiroshi ^a   Iwano, Shunsuke ^a   Kiyotani, Kazuma ^a   Matsumura, Keiko ^a   Honda, Goro ^a   Nakagawa, Kazuko ^a   Ishizaki, Takashi ^a   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE RECEPTOR AFFECTING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CYP3A PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYP3A5 PROTEIN, HUMAN; CYTOCHROME P450; DILTIAZEM; DNA; DRUG; MIDAZOLAM; PRIMER DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; TESTOSTERONE;

ARTICLE; DEALKYLATION; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; GENOTYPE; HUMAN; HYDROXYLATION; IN VITRO STUDY; JAPAN; KINETICS; LIVER MICROSOME; METABOLISM; OXIDATION REDUCTION REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CALCIUM CHANNEL BLOCKERS; CYTOCHROME P-450 ENZYME SYSTEM; DEALKYLATION; DILTIAZEM; DNA; DNA PRIMERS; ESCHERICHIA COLI; GABA MODULATORS; GENOTYPE; HUMANS; HYDROXYLATION; JAPAN; KINETICS; MICROSOMES, LIVER; MIDAZOLAM; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PHARMACEUTICAL PREPARATIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TESTOSTERONE;

EID: 4644263308     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.19.120     Document Type: Article

References (0)