Identification of immunodominant epitopes of Schistosoma mansoni vaccine candidate antigens using human T cells

Memorias do Instituto Oswaldo Cruz

Volumn 99, Issue 5, 2004, Pages 63-66

  Fonseca, C T ^a   Cunha Neto, E ^b   Kalil, J ^b   De Jesus, A R ^c   Correa Oliveira, R ^d   Carvalho, E M ^c   Oliveira, S C ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Paramyosin; Schistosoma mansoni; Sm14; Synthetic peptides; T cells; Vaccines

Indexed keywords

ANTIGEN SM14; EPITOPE; HLA DR ANTIGEN; PARAMYOSIN; SCHISTOSOMA VACCINE; UNCLASSIFIED DRUG;

CELL PROLIFERATION; COMPUTER PROGRAM; CONFERENCE PAPER; CONTROLLED STUDY; ENDEMIC DISEASE; HUMAN; HUMAN CELL; PEPTIDE SYNTHESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; T LYMPHOCYTE;

MURINAE; SCHISTOSOMA; SCHISTOSOMA MANSONI;

EID: 4644262104     PISSN: 00740276     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0074-02762004000900011     Document Type: Conference Paper

References (20)

1. Agiro L, Henri S, Dessein H, Kouriba B, Dessein AJ, Bourgois A 2000. Induction of protection against S. mansoni with a MAP containing epitopes of Sm37-GAPDH and Sm10-DLC. Effect of coadsorbtion with GM-CSF on alum. Vaccine 18: 2033-2038.
2. Al-Sherbiny M, Osman A, Barakat R, El Morshedy H, Bergquit R, Olds R 2003. In vitro cellular and humoral responses to Schistosoma mansoni vaccine candidate antigens. Acta Trop 88: 117-130.
3. Bergquist NR 1995. Schistosomiasis vaccine development: approaches and prospects. Mem Inst Oswaldo Cruz 90: 221-227.
4. Bergquist NR 1998. Schistosomiasis vaccine development: progress and prospects. Mem Inst Oswaldo Cruz 93: 95-101.
5. Bergquist NR 2002. Schistosomiasis: from risk assessment to control. Trends Parasitol 18: 309-314.
6. Bradford MM 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
7. Brito CF, Caldas IR, Coura Filho P, Correa-Oliveira R, Oliveira SC 2000a. CD4+ T cells of schistosomiasis naturally resistant individuals living in an endemic area produce interferon-gamma and tumour necrosis factor-alpha in response to the recombinant 14kDa Schistosoma mansoni fatty acid-binding protein. Scand J Immunol 51: 595-601.
8. Brito CF, Fonseca CT, Goes AM, Azevedo V, Simpson AJ, Oliveira SC 2000b. Human IgG1 and IgG3 recognition of Schistosoma mansoni 14kDa fatty acid-binding recombinant protein. Parasite Immunol 22: 41-48.
9. Colley DG, Cook JA, Freeman Jr GL, Bartholomew RK, Jordan P 1977. Immune responses during human schistosomiasis mansoni. I. In vitro lymphocyte blastogenic responses to heterogeneous antigenic preparations from schistosome eggs, worms and cercariae. Int Arch Allergy Appl Immunol 53: 420-433.
10. Correa-Oliveira R, Pearce EJ, Oliveira GC, Golgher DB, Katz N, Bahia LG, Carvalho OS, Gazzinelli G, Sher A 1989. The human immune response to defined immunogens of Schistosoma mansoni: elevated antibody levels to paramyosin in stool-negative individuals from two endemic areas in Brazil. Trans R Soc Trop Med Hyg 83: 798-804.
11. Fonseca CT, Brito CF, Alves JB, Oliveira SC 2004. IL-12 enhances protective immunity in mice engendered by immunization with recombinant 14 kDa Schistosoma mansoni fatty acid-binding protein through an IFN-gamma and TNF-alpha dependent pathway. Vaccine 22: 503-510.
12. Harder A 2002. Chemotherapeutic approaches to schistosomes: current knowledge and outlook. Parasitol Res 88: 395-397.
13. Lanar DE, Pearce EJ, James SL, Sher A 1986. Identification of paramyosin as schistosome antigen recognized by intradermally vaccinated mice. Science 234: 593-596.
14. Moser D, Tendler M, Griffiths G, Klinkert MQ 1991. A 14-kDa Schistosoma mansoni polypeptide is homologous to a gene family of fatty acid binding proteins. J Biol Chem 266: 8447-8454.
15. Nara T, Tanabe K 1997. The B-cell epitope of paramyosin recognized by a protective monoclonal IgE antibody to Schistosoma mansoni. Vaccine 15: 79-84.
16. Pearce EJ, James SL, Hieny S, Lanar DE, Sher A 1988. Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen. Proc Natl Acad Sci USA 85: 5678-5682.
17. Ribeiro de Jesus A, Araujo I, Bacellar O, Magalhaes A, Pearce E, Harn D, Strand M, Carvalho EM 2000. Human immune responses to Schistosoma mansoni vaccine candidate antigens. Infect Immun 68: 2797-2803.
18. Tallima H, Montash M, Veprek P, Velek J, Jezek J, El Ridi R 2003. Differences in immunogenicity and vaccine potential of peptides from Schistosoma mansoni glyceraldehyde 3-phosphate dehydrogenase. Vaccine 21: 3290-3300.
19. Tarrab-Hazdai R, Schechtman D, Arnon R 1998. Synthesis and characterization of a protective peptide-based vaccine against Schistosoma mansoni. Infect Immun 66: 4526-4530.
20. Vilar MM, Barrientos F, Almeida M, Thaumaturgo N, Simpson A, Garratt R, Tendler M 2003. An experimental bivalent peptide vaccine against schistosomiasis and fascioliasis. Vaccine 22: 137-144.