A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3′-ethynyl nucleosides

Drug Metabolism and Disposition

Volumn 32, Issue 10, 2004, Pages 1178-1182

  Murata, Daigo ^a   Endo, Yoshio ^a   Obata, Tohru ^a   Sakamoto, Kazuki ^b   Syouji, Yasuhiro ^a   Kadohira, Masakazu ^a   Matsuda, Akira ^c   Sasaki, Takuma ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 C ETHYNYL BETA DEXTRO RIBOPENTOFURANOSYL)URIDINE; 3' ETHYNYL NUCLEOSIDE; 3' ETHYNYLCYTIDINE; NUCLEOSIDE; RNA POLYMERASE; UNCLASSIFIED DRUG; URIDINE CYTIDINE KINASE 1; URIDINE CYTIDINE KINASE 2; URIDINE KINASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; CROSS RESISTANCE; CYTOTOXICITY TEST; DELETION MUTANT; DNA SEQUENCE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXON; GENE; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SOLID TUMOR; TUMOR CELL LINE; UCK2 GENE; XENOGRAFT;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYTIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; POINT MUTATION; URIDINE; URIDINE KINASE;

EID: 4644261162     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.000737     Document Type: Article

References (14)

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