The miniature pig: A unique experimental model for Schistosoma japonicum infection

Parasitology International

Volumn 53, Issue 4, 2004, Pages 293-299

  Watanabe, Kanji ^a   Kikuchi, Mihoko ^a   Ohno, Akio ^a   Taha Mohamed, Raafat ^a   Nara, Takeshi ^b   Ubalee, Ratawan ^a   Senba, Masachika ^a   Iwasaki, Takuya ^a   Chen, Honggen ^c   Aoki, Yoshiki ^a   Hirayama, Kenji ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c Jiangxi Prov Inst Parasitic Dis   (China)

Author keywords

Animal model; EPG (eggs number per 1 gram feces); MHC (major histocompatibility complex); Miniature pig; Schistosoma japonicum; SEA (schistosome soluble egg antigens); SLA (swine leukocyte antigen); SWA (schistosome adult worm antigens)

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FECES ANALYSIS; HISTOLOGY; INOCULATION; LIVER HISTOLOGY; LUNG; MESENTERY LYMPH NODE; NONHUMAN; PANCREAS; PARASITE IDENTIFICATION; PERFUSION; PRIORITY JOURNAL; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS; SEROLOGY; SMALL INTESTINE; SPLEEN; SWINE;

ANIMALS; ANTIBODIES, HELMINTH; DISEASE MODELS, ANIMAL; FECES; FEMALE; HUMANS; MALE; PARASITE EGG COUNT; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; SWINE; SWINE, MINIATURE;

ANIMALIA; SCHISTOSOMA; SCHISTOSOMA JAPONICUM; SUS SCROFA;

EID: 4644260267     PISSN: 13835769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parint.2004.03.002     Document Type: Article

References (16)

1. WHO. Report of the WHO informal Consultation on schistosomiasis control. 1998;WHO, Geneva
2. Qingwu J., Shaoji Z., Hongchang Y., Zide L., Genming Z., Brinkmann U. The effect of a combined approach to schistosomiasis control on the transmission of Schistosoma japonicum in Xingzi of Poyang Lake Area, China. Southeast Asian J Trop Med Public Health. 273:1996;535-541
3. Genming Z., Brinkmann U.K., Qingwu J., Shaoji Z., Zhide L., Hongchang Y. The relationship between morbidity and intensity of Schistosoma japonicum infection of a community in Jiangxi Province, China. Southeast Asian J Trop Med Public Health. 283:1997;545-550
4. Von Lichtenberg F., Sadun E.H., Cheever A.W., Erickson D.G., Johnson A.J., Boyce H.W. Experimental infection with Schistosoma japonicum in chimpanzees. Am J Trop Med Hyg. 206:1971;850-893
5. Basch P.F. Schistosomiasis. 1991;Oxford University Press, Oxford
6. Willingham AL, 3rd, Hurst M. The pig as a unique host model for Schistosoma japonicum infection. 1996;12:132-134
7. Willingham A.L. 3rd, Hurst M., Bogh H.O., Johansen M.V., Lindberg R., Christensen N.O., et al. Schistosoma japonicum in the pig: the host-parasite relationship as influenced by the intensity and duration of experimental infection. Am J Trop Med Hyg. 582:1998;248-256
8. Chen H., Nara T., Zeng X., Satoh M., Wu G., Jiang W., et al. Vaccination of domestic pig with recombinant paramyosin against Schistosoma japonicum in China. Vaccine. 1820:2000;2142-2146
9. Hurst M.H., Shi Y.E., Lindberg R. Pathology and course of natural Schistosoma japonicum infection in pigs: results of a field study in Hubei province, China. Ann Trop Med Parasitol. 945:2000;461-477
10. Hurst M.H., Willingham A.L. 3rd, Lindberg R. Tissue responses in experimental schistosomiasis japonica in the pig: a histopathologic study of different stages of single low- or high-dose infections. Am J Trop Med Hyg. 621:2000;45-56
11. Johansen M.V., Bogh H.O., Nansen P., Christensen N.O. Schistosoma japonicum infection in the pig as a model for human schistosomiasis japonica. Acta Tropica. 76:2000;85-99
12. Reid W.A., von Lichtenberg F. Experimental Schistosoma japonicum infection in miniature pigs. J Parasitol. 632:1977;392-394
13. Yason C.V., Novilla M.N. Clinical and pathologic features of experimental Schistosoma japonicum infection in pigs. Vet Parasitol. 171:1984;47-64
14. Kardorff R., Eriksen L., Nielsen D.H., Johansen M.V. Validation of ultrasonography for hepatic schistosomiasis using a porcine Schistosoma japonicum model. Acta Tropica. 85:(3):2003;315-323
15. Hurst M.H., Willingham A.L., Lindberg R. Experimental schistosomiasis japonica in the pig: immunohistology of the hepatic egg granuloma. Parasite Immunol. 24:(3):2002;151-159
16. Chardon P., Renard C., Vaiman M. The major histocompatibility complex in swine. Immunol Rev. 167:1999;179-192