Combination of α-fetoprotein mRNA-based detection of hematogenously disseminating hepatocellular carcinoma cells and analysis of cancer cell membrane fluidity is more accurate in screening patients at risk of postoperative recurrence

Oncology Reports

Volumn 11, Issue 3, 2004, Pages 637-639

  Funaki, Naomi ^a   Tanaka, Junji ^b   Kono, Yukihiro ^a   Nonaka, Atsushi ^a   Yotsumoto, Fumiaki ^a   Lee, Jeon Uk ^a   Imamura, Masayuki ^c  

^a SHIGA MEDICAL CENTER FOR ADULTS   (Japan)

^b Keihanna Hospital   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Hematogenous dissemination; Hepatocellular carcinoma; Membrane fluidity; Recurrence; fetoprotein mRNA

Indexed keywords

ALPHA FETOPROTEIN; COMPLEMENTARY DNA; MESSENGER RNA; RNA;

ARTICLE; CELL MEMBRANE; FLUORESCENCE MICROSCOPY; HUMAN; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MORTALITY; POLYMERASE CHAIN REACTION; PROGNOSIS; RECURRENT DISEASE; TREATMENT OUTCOME; TUMOR CELL LINE;

ALPHA-FETOPROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MEMBRANE; DNA, COMPLEMENTARY; HUMANS; LIVER; LIVER NEOPLASMS; MICROSCOPY, FLUORESCENCE; POLYMERASE CHAIN REACTION; PROGNOSIS; RECURRENCE; RNA; RNA, MESSENGER; TREATMENT OUTCOME;

EID: 4644240606     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.11.3.637     Document Type: Article

References (17)

1. Okuda K, Kotoda K, Obata H, Hayashi N and Hisamatsu T: Clinical observations during a relatively early stage of hepatocellular carcinoma, with special reference to serum-alpha fetoprotein. Gastroenterology 69: 226-234, 1975.
2. Smith B, Selbe P, Southgate J, Pittman K, Bradley C and Blair E: Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet 338: 1227-1229, 1991.
3. Datta HD, Adams PT, Drobyski WR, Ethier S, Terry VH and Roth MS: Sensitive detection of occult breast cancer by the reverse-transcriptase polymerase chain reaction. J Clin Oncol 12: 475-482, 1994. (Pubitemid 24079887)
4. Wood DP Jr, Banks ER, Humphreys S, McRoberts JW and Rangnekar VM: Detection of tyrosin hydroxylase mRNA and minimal neuroblastoma cells by the reverse transcription-polymerase chain reaction. Eur J Cancer 27: 762-765, 1991.
5. Funaki N, Tanaka J, Seto S, Kasamatsu T, Kaido T and Imamura M: Highly-sensitive identification of alpha-fetoprotein mRNA in circulating peripheral blood of hepatocellular carcinoma patients. Life Sci 57: 1621-1631, 1995.
6. Funaki ON, Tanaka J, Kasamatsu T, Seto S, Kaido T and Imamura M: Hematogenous spreading hepatocellular carcinoma cells: possible participation in recurrence in the liver. Hepatology 25: 564-568, 1997. (Pubitemid 27106434)
7. Funaki NO, Tanaka J and Imamura M: Quantitative analysis of alpha-fetoprotein mRNA in circulating peripheral blood of patients with hepatocellular and alpha-fetoprotein-producing gastric carcinomas. Life Sci 62: 1973-1984, 1998. (Pubitemid 28234306)
8. Yoshida M, Tanaka J, Tamura J, Kohmoto M, et al: Altered fluidity of liver plasma membranes following partial hepatectomy in rats. J Surg Res 55: 390-396, 1993. (Pubitemid 23346879)
9. Kohmoto M, Tanaka J, Yoshida M, Kasamatsu T, Fujita KI, Zhong WB, Kaidou T, Tamura I and Imamura M: Plasama membrane fluidity during regeneration and atrophy of the rat liver following portal branch ligation. Eur Surg Res 26: 221-229, 1994. (Pubitemid 24189425)
10. Chapman D: Biomembrane fluidity: the concept and its development. In: Membrane Fluidity in Biology. Aloia RC (ed). Vol. 12. Academic Press, New York, pp5-42, 1983.
11. Shinitzky M: Membrane fluidity and cellular functions. In: Physiology of Membrane Fluidity. Shinitzky M (ed). CRC Press, Boca Raton, FL, pp1-51, 1982.
12. Funaki NO, Tanaka I, Kphmoto M, Sugiyama T, Ohshio G, Nonaka A, Yotsumoto F, Takeda Y and Imamura M: Membrane fluidity correlates with liver cancer cell proliferation and infiltration potential. Oncol Rep 8: 527-532, 2001. (Pubitemid 33758448)
13. Cheng S and Levy D: The effects of cell proliferation on the lipid composition and fluidity of hepatocytes plasma membranes. Arch Biochem Biophys 196: 424-429, 1979. (Pubitemid 10230155)
14. Chomczynski P and Sacchi N: Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987. (Pubitemid 17064313)
15. Morinaga T, Sakai M, Wegmann TG and Tamaoki T: Primary structures of human alpha-fetoprotein and its mRNA. Proc Natl Acad Sci USA 80: 4604-4608, 1983. (Pubitemid 13030973)
16. Maeda T, Balakrishnan K and Mehdi SQ: A simple and rapid method for the separation of plasma membranes. Biochem Biophys Acta 731: 115-120, 1983. (Pubitemid 13100770)
17. Kano-Sueoka T, King DM and Fisk HA: Binding of epidermal growth factor to its receptor is affected by membrane phospholipid environment. J Cell Physiol 145: 543-548, 1990. (Pubitemid 120027396)