Effects of chard (Beta vulgaris L. var cicla) on the liver of the diabetic rats: A morphological and biochemical study

Bioscience, Biotechnology and Biochemistry

Volumn 68, Issue 8, 2004, Pages 1640-1648

  Ozsoy Sacan, Ozlem ^a   Karabulut Bulan, Omür ^a   Bolkent, Sehnaz ^a   Yanardag, Refiye ^a   Ozgey, Yasemin ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Beta vulgaris L. var cicla; Chard; Hepatic regeneration; Liver; Streptozotocin

Indexed keywords

ALANINE; ALKALINE PHOSPHATASE; GLUTATHIONE; PLANT MEDICINAL PRODUCT;

ANIMAL; ARTICLE; BEET; BLOOD; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; DIABETES MELLITUS; DRUG EFFECT; GLUCOSE BLOOD LEVEL; LIPID PEROXIDATION; LIVER; METABOLISM; PATHOLOGY; PHYSIOLOGY; RAT; SERUM; TRANSMISSION ELECTRON MICROSCOPY;

ALANINE; ALKALINE PHOSPHATASE; ANIMALS; BETA VULGARIS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS; GLUTATHIONE; LIPID PEROXIDATION; LIVER; MICROSCOPY, ELECTRON, TRANSMISSION; PLANT PREPARATIONS; RATS; SERUM;

ANIMALIA; AVES; BETA VULGARIS; BETA VULGARIS CICLA; BETA VULGARIS SUBSP. VULGARIS; LABRUS; MELEAGRIS GALLOPAVO;

EID: 4644231359     PISSN: 09168451     EISSN: None     Source Type: Journal    
DOI: 10.1271/bbb.68.1640     Document Type: Article

References (51)

1. Seghrouchni, I., Drai, J., Bannier, E., Riviére, J., Calmard, P., Garcia, I., Origiazzi, J., and Revol, A., Oxidative stress parameters in type I, type II and insulin-treated type 2 diabetes mellitus; insulin treatment efficiency. Clin. Chim. Acta, 321, 89-96 (2002).
2. Arun, N., and Nalini, N., Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats. Plant Foods Human Nutr., 57, 41-52 (2002).
3. Kesavulu, M. M., Kameswara Rao, B., Giri, R., Vijaya, J., Subramanyam, G., and Apparao, C., Lipid peroxidation and antioxidant enzyme status in Type 2 diabetics with coronary heart disease. Diabetes Res. Clin. Prac., 53, 33-39 (2001).
4. Hunt, J. V., Smith, C. C., and Wolff, S.P., Autooxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes, 39, 1420-1424 (1999).
5. Grover, J. K., Yadav, S., and Vats, V., Medicinal plants of Indiana with anti-diabetic potential. J. Ethnopharmacol., 81, 81-100 (2002).
6. Neef, H., Declercq, P., and Laekeman, G., Hypoglycemic activity of selected European plants. Phytother. Res., 9, 45-48 (1995).
7. Yanardaǧ, R., and Çolak, H., Effect of Chard (Beta vulgaris L. var cicla) on blood glucose levels in normal and alloxan-induced diabetic rabbits. Pharm. Pharmacol. Commun., 4, 309-311 (1998).
8. Yarat, A., Özçelik, F., Yanardaǧ, R., Tunali, T., Özsoy, Ö., Emekli, N., and Üstünel, A., The effect of chard (Beta vulgaris L. var. cicla) on the protein and antioxidant systems in lenses of streptozotocin-induced diabetic rats. Pharm. Pharmacol. Commun., 4, 271-274 (1998).
9. Tunali, T., Yarat, A., Yanardaǧ, R., Özçelik, F., Özsoy, Ö., Ergenekon, G., and Emekli, N., The effect of chard (Beta vulgaris L. var. cicla) on the skin of streptozotocin induced diabetic rats. Pharmazie, 53, 638-640 (1998).
10. Yanardaǧ, R., Bolkent, Ş., Özsoy-Saçan, Ö., and Karabulut-Bulan, Ö., The effect of chard (Beta vulgaris L. var. cicla) extract on the kidney tissue, serum urea and creatinine levels of diabetic rats. Phytother. Res., 16, 758-761 (2002).
11. Secchi, G., The lipids of the leaves as a source of essential fatty acids in the diet. Rass. Chim., 15, 118-121 (1963).
12. Zeller, W., Rudolph, K., and Hoppe, H. H., Effect of the pseudomonas phaseolicolatoxinon on the composition of lipids in leaves of Swiss chard II. Changes in the fatty acid spectrum of phospholipids and glycolipids. Phytopathol., 89, 296-305 (1977).
13. Potter, E. F., and Long, M. C., Sugar determination in green and leafy plants and dried forages. J A O A C., 48, 728-730 (1965).
14. Pokluda, R., and Kuben, J., Comparison of selected Swiss chard (Beta vulgaris ssp. cicla L.) varieties. Hort. Sci. (Prague), 29, 114-118 (2002).
15. Pager, E. E. C., Olson, O. E., Burris, R. H., and Elvehjem, A. C., Folic acid in vegetables and certain other plant materials. Food Res., 14, 1-8 (1949).
16. Elwell, W. E., and Dehn, W. M., Pectic content of plant materials. Plant Physiol., 14, 809-816 (1939).
17. Masayuki, Y., and Shoichi, H., Japan Kokai Tokkyo Koho, 09 25290 (Appl. 95/177.220, 1995).
18. Djioux, M. G., Lavaud, C., Massiot, G., and Le men-Oliver, L., Flavonoids from Beta vulgaris varieties. Fitoterapia, LXVI, 195 (1995).
19. Junod, A., Lambert, A. E., Stauffacher, W., and Renold, A. E., Diabetogenic action of streptozotocin: relationship of dose to metabolic response. J. Clin. Invest., 48, 2129-2139 (1969).
20. Relander, A., and Raiha, C. E., Differences between the enzymatic and o-toluidine methods of blood glucose detemination. Scand. J. Clin. Lab. Invest., 15, 221-224 (1963).
21. Beutler, E., Duron, O., and Kelly, B. M., Improved method for the determination of blood glutathione. J. Lab. Clin. Med., 61, 882-888 (1963).
22. Reitman, S., and Frankel, S. A., Colorometric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am. J. Clin. Pathol., 8, 56-63 (1957).
23. Walter, K., and Schütt, C., Acid and alkaline phosphatase in serum (two point method). In "Methods of Enzymatic Analysis" Vol 2, ed. Bergmeyer, H. U., Florida, pp. 856-860 (1974).
24. Frings, C. S., Fendley, T. W., Dunn, R. T., and Queen, C. A., Improved determination of total serum lipids by the sulfophospho-vanilin reaction. Clin. Chem., 18, 673-674 (1972).
25. Lorentz, K., Weiss, T., and Kraas, E., Sialic acid in human serum and cerebrospinal fluid. J. Clin. Chem. Biochem., 24, 189-198 (1986).
26. Caraway, W. T., Determination of uric acid in serum by a carbonate method. Am. J. Clin. Pathology, 25, 840-845 (1955).
27. Beutler, E., "Glutathione in Red Cell Metabolism: A Manual of Biochemical Methods" 2nd ed., Grune and Stratton, New York, pp. 112-114 (1975).
28. Ledwozwy, A., Michalak, J., Stepien, A., and Kadziolka, A., The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis. Clin. Chim. Acta, 155, 275-284 (1986).
29. Parker, K. M., England, J. D., Casto, J. D., Hessel, K., and Goldstein, P. E., Improved colorimetric assay for glycolylated hemoglobin. Clin. Chem., 27, 669-672 (1981).
30. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., Protein measurement with the folin phenol reagent. J. Biol. Chem., 193, 265-275 (1951).
31. Hintze, J. L., Copyright C, 865, East 400, North Kaysville, Utah, 84,037 (801), 546-0445 (1986).
32. Pari, L., and Umamaheswari, J., Antihyperglycaemic activity of Musa sapientum flowers: effect on lipid peroxidation in alloxan diabetic rats. Phytoter. Res., 14, 136-138 (2000).
33. Tekman, Ş., and Öner, N., Genel Biokimya İstanbul Üniversitesi Yayinlari Emek Matbaacilik, 6. Baski, pp. 128 (1998).
34. Bolkent, Ş., Yanardaǧ, R., Tabakoǧlu-Oǧuz, A., and Özsoy-Saçan, Ö., Effects of chard (Beta vulgaris L. var cicla) extract on pancreatic B cells in streptozotocin diabetic rats: a morphological and biochemical study. J. Ethnopharmacol., 73, 251-259 (2000).
35. Chaudry, A. R., Alam, M., Ahmad, M., Khan, F. Z., and Nomani, N., Studies on medicinal herbs. II: Effect of Colchicum luteum on biochemical parameters of rabbit serum. Fitoterapia, 64, 510-515 (1993).
36. Baraona, E., Pikkarainen, P., Salaspuro, M., Finkelman, F., and Lieber, C. S., Acute effects of ethanol on hepatic protein synthesis and secretion in the rat. Gastroenterol., 79, 104 (1980).
37. Saladini, M., Menabue, L., and Ferrari, E., Binding ability of sialic acid towards biological and toxic metal ions. NMR, potentiometric and spectroscopic study. J. Inorg. Biochem., 88, 61-68 (2002).
38. Sönmez, H., Süer, S., Güngör, Z., Kökoǧlu, E., and Isbir, T., Sialidase activities and sialic acid levels of the liver and serum from streptozotocin induced diabetic rats. Diabetes Res., 32, 101-106 (1997).
39. Vannucchi, H., Araujo, W. F., Bernardes, M. M., and Jordao-JR, A. A., Effect of different vitamin E levels on lpid peroxidation in streptozotocin-diabetic rats. Int. J. Vitam. Nutr. Res., 69, 250-254 (1999).
40. Machlin, L. J., and Bendich, A., Free radical tissue damage: protective role of antioxidant nutritients. FASEB. J., 1, 441-445 (1987).
41. Sano, T., Umeda, F., Nawata, H., and Utsumi, H., Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes. Diabetologia, 41, 1355-1360 (1998).
42. Venkateswaran, S., and Pari, L., Effect of Coccinia indica leaves on antioxidant status in streptozotocin-induced diabetic rats. J. Ethnopharmacol., 84, 163-168 (2003).
43. Yue, D. K., Mc Lennan, S., and Turtle, J. R., Non-enzymatic glycosylation of tissue protein in diabetes in the rat. Diabetologia, 24, 377-381 (1983).
44. Anderson, R. A., Roussel, A. M., Zouari, N., Mahjoub, S., Matheau, J. M., and Kerkeni, A., Potential anti-oxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus. J. Am. Coll. Nutr., 20, 212-218 (2001).
45. Kinalski, M., Sledziewski, A., Telejko, B., Zarzycki, W., and Kinalska, I., Lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes. Acta Diabetol., 37, 179-183 (2000).
46. Prakasam, A., Sethupaty, S., and Pugalendi, K. V., Effect of Casearia esculenta root extraction on blood glucose and plasma antioxidant status in streptozotocin diabetic rats. Polish J. Phamacol., 55, 43-49 (2003).
47. Ravikumar, P., and Anuradha, C. V., Effect of fenugreek seeds on blood lipid peroxidation and antioxidants in diabetic rats. Phytother. Res., 13, 197-201 (1999).
48. Wang, H. X., and Ng, T. B., Natural products with hypoglycemic, hypotensive, hypocholesterolemic, anti-atherosclerotic and antithronbotic activities. Life Sci., 6, 2663-2677 (1999).
49. Sheweita, S. A., Newairy, A. A., Mansour, H. A., and Yousef, M. I., Effect of some hypoglycemic herbs on the activity of phase I and II drug-metabolizing enzymes in alloxan-induced diabetic rats. Toxicology, 174, 131-139 (2002).
50. Prashanth Kumar, V., Shashidhara, S., Kumar, M. M., and Sridhara, B. Y., Effect of Luffa echinata on lipid peroxidation and free radical scavenging activity. J. Pharm. Pharmacol., 52, 891-894 (2000).
51. Kameswara Rao, B., Renuka Sudarshan, P., Rajasekhar, M. D., Nagaraju, N., and Appa Rao, C., Antidiabetic activity of Terminalia pallida fruit in alloxan induced diabetic rats. J. Ethnopharmacol., 85, 169-172 (2003).