Partial proteolysis of simian virus 40 T antigen reveals intramolecular contacts between domains and conformation changes upon hexamer assembly

Journal of Biological Chemistry

Volumn 279, Issue 37, 2004, Pages 38943-38951

  Weisshart, Klaus ^a,c   Friedl, Sabine ^a   Taneja, Poonam ^b,d   Nasheuer, Heinz Peter ^a,e   Schlott, Bernhard ^a   Grosse, Frank ^a   Fanning, Ellen ^b  

^a FRITZ LIPMANN INSTITUTE   (Germany)

^b VANDERBILT UNIVERSITY   (United States)

^c CARL ZEISS SMT AG   (Germany)

^d Arcturus Bioscience Inc   (United States)

^e NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; ANTIBODIES; ANTIGENS; BIOCHEMISTRY; DNA; MOLECULAR BIOLOGY; PROTEINS; TUMORS;

HEXAMERIZATION; PROTEOLYSIS; TRYPTIC DIGESTION; TUMOR ANTIGEN (TAG);

VIRUSES;

ADENOSINE TRIPHOSPHATE MAGNESIUM; EPITOPE; HELICASE; HEXAMER; MONOCLONAL ANTIBODY; MONOMER; TRYPSIN; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS LARGE T ANTIGEN; VIRUS PROTEIN;

ARTICLE; C TERMINAL DOMAIN; CENTRAL DOMAIN; CONFORMATIONAL TRANSITION; MOLECULAR INTERACTION; N TERMINAL DOMAIN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; SIMIAN VIRUS 40; STRUCTURAL DOMAIN; TAG DOMAIN; VIRUS REPLICATION; VIRUS REPLISOME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BINDING SITES; CELL LINE; DNA HELICASES; EPITOPES; INSECTS; MODELS, BIOLOGICAL; PEPTIDES; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TRYPSIN;

DNA VIRUSES; SIMIAE; SIMIAN VIRUS 40;

EID: 4644229651     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406159200     Document Type: Article

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