Quality use of medicines: A new method of combining antibiotic consumption and sensitivity data - Application in a Russian hospital

Pharmacoepidemiology and Drug Safety

Volumn 17, Issue 6, 2008, Pages 636-644

  Goryachkina, Ksenia ^a,b   Babak, Svetlana ^a   Burbello, Aleksandra ^a   Wettemark, Björn ^b   Bergman, Ulf ^b  

^a NORTH WESTERN STATE MEDICAL UNIVERSITY NAMED AFTER I I MECHNIKOV   (Russian Federation)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Antibiotic use; Hospital care; Quality assessment; Resistance; Russia

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AMPICILLIN PLUS OXACILLIN; AZITHROMYCIN; CEFAZOLIN; CEFEPIME; CEFTRIAXONE; CILASTATIN PLUS IMIPENEM; CIPROFLOXACIN; CLARITHROMYCIN; DOXYCYCLINE; ERYTHROMYCIN; GENTAMICIN; KANAMYCIN; LINCOMYCIN; LINEZOLID; MEROPENEM; METRONIDAZOLE; MOXIFLOXACIN; NORFLOXACIN; OFLOXACIN; OXACILLIN; PEFLOXACIN MESILATE; PENICILLIN G; PIPEMIDIC ACID; SULTAMICILLIN; TETRACYCLINE; UNINDEXED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; COST EFFECTIVENESS ANALYSIS; DRUG COST; DRUG EFFICACY; DRUG QUALITY; DRUG USE; DRUG UTILIZATION; HOSPITAL BED UTILIZATION; HUMAN; PRIORITY JOURNAL; RUSSIAN FEDERATION; ECONOMICS; HEALTH CARE QUALITY; HOSPITAL BED CAPACITY; INFORMATION PROCESSING; METHODOLOGY; STANDARD; UNIVERSITY HOSPITAL;

ANTI-BACTERIAL AGENTS; DATA COLLECTION; DRUG RESISTANCE, BACTERIAL; DRUG UTILIZATION; HOSPITAL BED CAPACITY, 500 AND OVER; HOSPITALS, UNIVERSITY; HUMANS; QUALITY ASSURANCE, HEALTH CARE; QUALITY INDICATORS, HEALTH CARE; RUSSIA;

EID: 46349107413     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.1543     Document Type: Article

References (33)

1. Pedersen KB, Rosdahl VT. The Copenhagen recommendations report from the Invitational EU Conference on The Microbial Threat, Copenhagen, Denmark 9-10 September 1998, 52 blade (Ministry of Health Ministry of Food, [Kbh.], 1998).
2. Smitla RD, Coast J. Antimicrobial resistance: a global response. Bull World Health Organ 2002; 80: 126-133.
3. Cars O, Mölstad S, Melander A. Variation in antibiotic use in the European Union. Lancet 2001; 357: 1851-1853. DOI: 10.1016/ S0140-6736(00)04972-2
4. Gulbinovic J, Myrbäck KE, Bytautieně J, Wettermark B, Struwe J, Bergman U. Marked differences in antibiotic use and resistance between university hospitals in Vilnius, Lithuania, and Huddinge, Sweden. Microb Drug Resist 2001; 7: 383-389. DOI: 10.1089/ 10766290152773392
5. Vaccberi A, Bjerrum L, Resi D, Bergman U, Montanaro N. Antibiotic prescribing in general practice: striking differences between Italy (Ravenna) and Denmark (Funen). J Antimicrob Chemother 50: 989-997. DOI: 10.1093/jac/dkf239
6. Bronzwaer S, Buchholz U, Courvalin P, et al. Comparability of antimicrobial susceptibility test results from 22 European countries and Israel: an external quality assurance exercise of tbe European Antimicrobial Resistance Surveillance System (EARSS) in collaboration with the United Kingdom National External Quality Assurance Scheme (UK NEQAS). J Antimicrob Chemother 2002; 50: 953-964. DOI: 10.1093/jac/dkf231
7. Goossens H, Ferech M, Vander Stichele R, Elseviers M. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005; 365: 579-587. DOI: 10.1016/S0140-6736(05)17907-0
8. Vlahović-Palčevski V, Dumpis U, Mitt P, Gulbinovič J, Struwe J, Palčevski G, Štimac D, Lagergren Å, Bergman U. Benchmarking antimicrobial drug use at university hospitals in five European countries. Clin Microbiol Infect 2007; 13: 277-283. DOI: 10.1111/j.1469-0691.2006.01613.x
9. Vander Stichele RH, Elseviers MM, Ferech M, Blot S, Goossens H. Hospital consumption of antibiotics in 15 European countries: results of the ESAC Retrospective Data Collection (1997-2002). J Antimicrob Chemother 2006; 58: 159-167. DOI: 10.1093/jac/dkl147
10. Struwe J, Dumpis U, Gulbinovic J, Lagergren A, Bergman U. Healthcare associated infections in university hospitals in Latvia, Lithuania and Sweden: a simple protocol for quality assessment. Euro Surveill 2006; 11: 167-171.
11. Ronning M, Blix HS, Harbo BT, Strom H. Different versions of the anatomical therapeutic chemical classification system and the defined daily dose - are drug utilisation data comparable? Eur J Clin Pharmacol 2000; 56: 723-727, DOI: 10.1007/s002280000200
12. WHO. ATC index with DDDs, (World Health Organization: World Health Organisation Collaborating Centre for Drug Statistics Methodology, 2003-2005). Available at www.whocc.no/atcddd [accessed 30, June 2007].
13. WHO global strategy for containment of antimicrobial resistance http://www.who.int/csr/drugresist/guidance/en/ [accessed 30, June 2007].
14. Antibiotics and antimicrobial therapy http://www.antibiotic.ru/ index.php?newlang=eng [accessed 30, June 2007].
15. Stratchounski L, Bedenkov A, Hryniewicz W, et al. The usage of antibiotics in Russia and some countries in Eastern Europe. Int J Antimicrob Agents 2001; 18: 283-286. DOI: 10.1016/ S0924-8579(01)00381-8
16. Stratchounski LS, Dekhnitch AV, Kozlov RS. Infection control system in Russia. J Hosp Infect 2001; 49: 163-166. DOI: 10.1053/ jhin.2001.1042
17. Palcevski G, Ahel V, Vlahović-Palcevski V, et al. Antibiotic use profile at paediatric clinics in two transitional countries. Pharmacoepidemiol Drug Saf 2004; 13: 181-185. DOI: 10.1002/pds.880
18. Birkett D, Smet Pd, Ofori-Adjei D, Trolin I, Bergman U, Strøm H. Introduction to Drug Utilization Research, (WHO Library Cataloguing-in-Publication data, Oslo, 2003).
19. Sjöqvist F, Bergman U, Dahl M-L, Gustafsson L, Hensjö L-O. Drug and Therapeutics Committees: a Swedish experience. WHO Drug Inf 2002; 16: 207-213.
20. Bergman U, Popa C, Tomson Y, Wettermark B, Einarson TR, Åberg H, et al. Drug utilization 90% - a simple method for assessing the quality of drug prescribing. Eur J Clin Pharmacol 1998; 54: 113-118, DOI: 10.1007/s002280050431
21. Bergman U, Risinggård H, Vlahovic-Palcevski V, Ericsson O. Use of antibiotics at hospitals in Stockholm: a benchmarking project using internet. Pharmacoepidemiol Drug Saf 2004; 13: 465-471. DOI: 10.1002/pds.898
22. NCCLS - National Committee for Clinical Laboratory Standards www.nccls.org [accessed 30. June 2007].
23. O'Brien TF, Stelling JM. WHONET: an information system for monitoring antimicrobial resistance. Emerg Infect Dis 1995; 1: 66.
24. WHO. WHONET5 Microbiology Laboratory Database Software. in WHO/CDS/CSR/ DRS (1999).
25. Sjostedt S, Levin P, Kager L, Malmborg AS, Bergman U. Hospital and catchment area antibiotic utilization and bacterial sensitivity in primary infections following gastric surgery in Huddinge, Sweden. Eur J Clin Pharmacol 1990; 39: 211-216. DOI: 10.1007/BF00315098
26. Pestotnik SL, Classen DC, Evans RS, Burke JP. Implementing antibiotic practice guidelines through computer-assisted decision support: clinical and financial outcomes. Ann Intern Med 1996; 124: 884-890.
27. Mölstad S, Cars O. Major change in the use of antibiotics following a national programme: Swedish strategic programme for the rational use of antimicrobial agents and surveillance of resistance (STRAMA). Scand J Infect Dis 1999; 31: 191-195.
28. Vlahovic-Palcevski V, Morovic M, Palcevski G, Betica-Radic L. Antimicrobial utilization and bacterial resistance at three different hospitals. Eur J Epidemiol 2001; 17: 375-383. DOI: 10.1023/ A:1012742314070
29. Kuperman GJ, Gibson RF. Computer physician order entry: benefits, costs, and issues. Ann Intern Med 2003; 139: 31-39.
30. Coenen S, Ferech M, Goossens H. Antibiotic prescribing quality indicators, in ESF EMRC exploratory workshop. (7-9 September, 2005).
31. Rønning M, Blix HS, Strøm H, et al. Problems in collecting comparable national drug use data in Europe: the example of antibacterials. Eur J Clin Pharmacol 2003; 58: 843-849. DOI: 10.1007/s00228-003-0572-8
32. Gendel I, Azzam ZS, Braun E, Levy Y, Krivoy N. Antibiotic utilization prevalence: prospective comparison between two medical departments in a tertiary care university hospital. Pharmacoepidemiol Drug Saf 2004; 13: 735-739. DOI: 10.1002/pds.976
33. Davey P, Brown E, Fenelon L, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev CD003543 2005. DOI: 10.1002/14651858.CD003543.pub2