Do we have a "best practice" for treating high altitude pulmonary edema?

High Altitude Medicine and Biology

Volumn 9, Issue 2, 2008, Pages 111-114

  Luks, Andrew M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Acetazolamide; High altitude; High altitude pulmonary edema; Nifedipine; Salmeterol; Sildenafil; Tadalafil

Indexed keywords

ACETAZOLAMIDE; ANTIBIOTIC AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DEXAMETHASONE; DIURETIC AGENT; MORPHINE; NICARDIPINE; NIFEDIPINE; PHOSPHODIESTERASE INHIBITOR; SALMETEROL; SILDENAFIL; TADALAFIL; VASODILATOR AGENT;

ALTITUDE DISEASE; BED REST; CLINICAL PRACTICE; DRUG EFFICACY; HIGH ALTITUDE PULMONARY EDEMA; HOSPITALIZATION; HUMAN; LUNG EDEMA; MORTALITY; OXYGEN THERAPY; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; REVIEW;

ADRENERGIC BETA-AGONISTS; ALTITUDE SICKNESS; ANTI-INFLAMMATORY AGENTS; CONTROLLED CLINICAL TRIALS AS TOPIC; DIURETICS; EVIDENCE-BASED MEDICINE; HUMANS; MOUNTAINEERING; OXYGEN INHALATION THERAPY; PRACTICE GUIDELINES AS TOPIC; PRIMARY PREVENTION; PULMONARY EDEMA; VASODILATOR AGENTS;

EID: 46249124981     PISSN: 15270297     EISSN: None     Source Type: Journal    
DOI: 10.1089/ham.2008.1017     Document Type: Review

References (26)

1. Bartsch P., Maggiorini M., Ritter M., Noti C., Vock P., and Oelz O. (1991). Prevention of high-altitude pulmonary edema by nifedipine. N. Engl. J. Med. 325:1284-1289.
2. Chou Y.T., Wang C.L., Kao K.C., Wu Y.K., and Tsai Y.H. (2007). High altitude pulmonary edema in a patient with previous pneumonectomy. J. Formosa. Med. Assoc. 106:320-322.
3. Dehnert C., Grunig E., Mereles D., von Lennep N., and Bartsch P. (2005). Identification of individuals susceptible to high-altitude pulmonary oedema at low altitude. Eur. Respir. J. 25:545-551.
4. Fagenholz P.J., Gutman J.A., Murray A.F., and Harris N.S. (2007). Treatment of high altitude pulmonary edema at 4240 m in Nepal. High Alt. Med. Biol. 8:139-146.
5. Faoro V., Huez S., Giltaire S., Pavelescu A., van Osta A., Moraine J.J., Guenard H., Martinot J.B., and Naeije R. (2007). Effects of acetazolamide on aerobic exercise capacity and pulmonary hemodynamics at high altitudes. J. Appl. Physiol. 103:1161-1165.
6. Freeman K., Shalit M., and Stroh G. (2004). Use of the Gamow bag by EMT-basic park rangers for treatment of high-altitude pulmonary edema and high-altitude cerebral edema. Wilderness Environ. Med. 15:198-201.
7. Gabry A.L., Ledoux X., Mozziconacci M., and Martin C. (2003). High-altitude pulmonary edema at moderate altitude (<2,400 m; 7,870 feet): a series of 52 patients. Chest. 123:49-53.
8. Hackett P.H., and Roach R.C. (2001). High-altitude illness. N. Engl. J. Med. 345:107-114.
9. Hackett P.H., Roach R.C., Hartig G.S., Greene E.R., and Levine B.D. (1992). The effect of vasodilators on pulmonary hemodynamics in high altitude pulmonary edema: a comparison. Int. J. Sports Med. 13 (Suppl 1):S68-S71.
10. Hohne C., Krebs M.O., Seiferheld M., Boemke W., Kaczmarczyk G., and Swenson E.R. (2004). Acetazolamide prevents hypoxic pulmonary vasoconstriction in conscious dogs. J. Appl. Physiol. 97:515-521.
11. Hultgren H.N., Honigman B., Theis M.K., and Nicholas D. (1996). High-altitude pulmonary edema at a ski resort. West. J. Med. 164:222-227.
12. Hultgren H.N., Lopez C.E., Lundberg E., and Miller H. (1964). Physiologic studies of pulmonary edema at high altitude. Circulation. 29:393-408.
13. Lobenhoffer R.A., Zink R.A., and Brendel W. (1982). High altitude pulmonary edema: analysis of 166 cases. High Altitude Physiology and Medicine. W. Brendel and R.A. Zink, eds. New York, Springer-Verlag; pp. 219-231.
14. Maggiorini M., Brunner-La Rocca H.P., Peth S., Fischler M., Bohm T., Bernheim A., Kiencke S., Bloch K.E., Dehnert C., Naeije R., Lehmann T., Bartsch P., and Mairbaurl H. (2006). Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial. Ann. Intern. Med. 145:497-506.
15. Marticorena E., and Hultgren H.N. (1979). Evaluation of therapeutic methods in high altitude pulmonary edema. Am. J. Cardiol. 43:307-312.
16. Menon N.D. (1965). High-altitude pulmonary edema: a clinical study. N. Engl. J. Med. 273:66-73.
17. Oelz O., Maggiorini M., Ritter M., Waber U., Jenni R., Vock P., and Bartsch P. (1989). Nifedipine for high altitude pulmonary oedema. Lancet. 2:1241-1244.
18. Sartori C., Allemann Y., Duplain H., Lepori M., Egli M., Lipp E., Hutter D., Turini P., Hugli O., Cook S., Nicod P., and Scherrer U. (2002). Salmeterol for the prevention of high-altitude pulmonary edema. N. Engl. J. Med. 346:1631-1636.
19. Scherrer U., Vollenweider L., Delabays A., Savcie M., Eichenberger U., Kleger G.R., Firkle A., Ballmer P., Nicod P., and Bartsch P. (1996). Inhaled nitric oxide for high-altitude pulmonary edema. N. Engl. J. Med. 334:624-629.
20. Schoene R.B., Roach R.C., Hackett P.H., Harrison G., and Mills W.J., Jr. (1985). High altitude pulmonary edema and exercise at 4,400 meters on Mount McKinley. Effect of expiratory positive airway pressure. Chest. 87:330-333.
21. Singh I., Lal M., Khanna P.K., and Mathew N.T. (1967). Augmentation of frusemide diuresis by morphine in high altitude pulmonary oedema. Br. Heart J. 29:709-713.
22. Sophocles A.M., Jr. (1986). High-altitude pulmonary edema in Vail, Colorado, 1975-1982. West. J. Med. 144:569-573.
23. Strote J., and Prutkin J. (2006). High-altitude pulmonary edema presenting 18 hours after descent. Wilderness Environ. Med. 17:137-139.
24. Teppema L.J., Balanos G.M., Steinback C.D., Brown A.D., Foster G.E., Duff H.J., Leigh R., and Poulin M.J. (2007). Effects of acetazolamide on ventilatory, cerebrovascular, and pulmonary vascular responses to hypoxia. Am. J. Respir. Crit. Care Med. 175:277-281.
25. Wu T. (2004). A Tibetan with chronic mountain sickness followed by high altitude pulmonary edema on reentry. High Alt. Med. Biol. 5:190-194.
26. Zafren K., Reeves J.T., and Schoene R. (1996). Treatment of high-altitude pulmonary edema by bed rest and supplemental oxygen. Wilderness Environ. Med. 7:127-132.