Role of the C-344T aldosterone synthase gene variant in left ventricular mass and left ventricular structure-related phenotypes

Heart

Volumn 94, Issue 7, 2008, Pages 903-910

  Sookoian, S ^a   Gianotti, T F ^a   Pirola, Carlos J ^a,b  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^b INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE SYNTHASE;

ARTICLE; DNA POLYMORPHISM; ETHNICITY; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE SIZE; HEART VENTRICLE SEPTUM; HOMOZYGOSITY; HUMAN; HYPERTENSION; HYPERTROPHIC CARDIOMYOPATHY; PHENOTYPE; PRIORITY JOURNAL; SYSTEMATIC REVIEW;

ALDOSTERONE SYNTHASE; DIASTOLE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEART VENTRICLES; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SYSTOLE;

EID: 46249118154     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/hrt.2007.119545     Document Type: Article

References (37)

1. De FU, Prince J. Genes and environment behind ethnical differences in variations in left ventricular mass. J Hypertens 2004;22:241- 3.
2. Kuznetsova T, Staessen JA, Thijs L, et al. Left ventricular mass in relation to genetic variation in angiotensin II receptors, renin system genes, and sodium excretion. Circulation 2004;110:2644-50.
3. White PC. Disorders of aldosterone biosynthesis and action. N Engl J Med 1994;331:250-8.
4. White PC, Slutsker L. Haplotype analysis of CYP11B2. Endocr Res 1995;21:437-42.
5. Bassett MH, Zhang Y, Clyne C, et al. Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1. J Mol Endocrinol 2002;28:125-35.
6. Kupari M, Hautanen A, Lankinen L, et al. Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function. Circulation 1998;97:569-75.
7. Stella P, Bigatti G, Tizzoni L, et al. Association between aldosterone synthase (CYP11B2) polymorphism and left ventricular mass in human essential hypertension. J Am Coll Cardiol 2004;43:265-70.
8. Isaji M, Mune T, Takada N, et al. Correlation between left ventricular mass and urinary sodium excretion in specific genotypes of CYP11B2. J Hypertens 2005;23:1149-57.
9. Rajput C, Makhijani K, Norboo T, et al. CYP11B2 gene polymorphisms and hypertension in highlanders accustomed to high salt intake. J Hypertens 2005;23:79-86.
10. Sarzani R, Salvi F, Dessi-Fulgheri P, et al. Aldosterone synthase alleles and cardiovascular phenotype in young adults. J Hum Hypertens 2003;17:859-64.
11. Heller S, Linhart A, Jindra A, et al. Association of -344/T/C aldosterone synthase polymorphism (CYP11B2) with left ventricular structure and humoral parameters in young normotensive men. Blood Press 2004;13:158-63.
12. Delles C, Erdmann J, Jacobi J, et al. Aldosterone synthase (CYP11B2) -344 C/T polymorphism is associated with left ventricular structure in human arterial hypertension. J Am Coll Cardiol 2001;37:878-84.
13. Kurland L, Melhus H, Karlsson J, et al. Polymorphisms in the angiotensinogen and angiotensin II type 1 receptor gene are related to change in left ventricular mass during antihypertensive treatment: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. J Hypertens 2002;20:657-63.
14. Patel R, Lim DS, Reddy D, et al. Variants of trophic factors and expression of cardiac hypertrophy in patients with hypertrophic cardiomyopathy. J Mol Cell Cardiol 2000;32:2369-77.
15. Schunkert H, Hengstenberg C, Holmer SR, et al. Lack of association between a polymorphism of the aldosterone synthase gene and left ventricular structure. Circulation 1999;99:2255-60.
16. Kuznetsova T, Staessen JA, Stolarz K, et al. Relationship between left ventricular mass and the ACE D/I polymorphism varies according to sodium intake. J Hypertens 2004;22:287-95.
17. Mayosi BM, Keavney B, Watkins H, et al. Measured haplotype analysis of the aldosterone synthase gene and heart size. Eur J Hum Genet 2003;11:395-401.
18. Bogardus ST Jr, Concato J, Feinstein AR. Clinical epidemiological quality in molecular genetic research: the need for methodological standards. JAMA 1999;281:1919-26.
19. Devereux RB, Lutas EM, Casale PN, et al. Standardization of M-mode echocardiographic left ventricular anatomic measurements. J Am Coll Cardiol 1984;4:1222-30.
20. Sahn DJ, DeMaria A, Kisslo J, et al. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58:1072-83.
21. Sookoian S, Gianotti TF, Gonzalez CD, et al. Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis. J Hypertens 2007;25:5-13.
22. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994;50:1088- 101.
23. Egger M, Davey SG, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.
24. Perneger TV. What's wrong with Bonferroni adjustments. BMJ 1998;316:1236-8.
25. Hengstenberg C, Holmer SR, Mayer B, et al. Evaluation of the aldosterone synthase (CYP11B2) gene polymorphism in patients with myocardial infarction. Hypertension 2000;35:704-9.
26. Porto PI, Garcia SI, Dieuzeide G, et al. Renin-angiotensin-aldosterone system loci and multilocus interactions in young-onset essential hypertension. Clin Exp Hypertens 2003;25:117-30.
27. Kurland L, Melhus H, Karlsson J, et al. Aldosterone synthase (CYP11B2) -344 C/T polymorphism is related to antihypertensive response: result from the Swedish lrbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. Am J Hypertens 2002;15:389-93.
28. Safar ME, Cattan V, Lacolley P, et al. Aldosterone synthase gene polymorphism, stroke volume and age-related changes in aortic pulse wave velocity in subjects with hypertension. J Hypertens 2005;23:1159- 66.
29. Olcay A, Nisanci Y, Ekmekci CG, et al. Aldosterone synthase -344C/T and angiotensin-converting enzyme I/D polymorphisms in Turkish hypertensive patients with normal coronary arteries. Acta Cardiol 2006;61:29-34.
30. Gosse P. Left ventricular hypertrophy as a predictor of cardiovascular risk. J Hypertens Suppl 2005;23:S27-S33.
31. Cuspidi C, Ambrosioni E, Mancia G, et al. Role of echocardiography and carotid ultrasonography in stratifying risk in patients with essential hypertension: the Assessment of Prognostic Risk Observational Survey. J Hypertens 2002;20:1307-14.
32. Verhaaren HA, Schieken RM, Mosteller M, et al. Bivariate genetic analysis of left ventricular mass and weight in pubertal twins (the Medical College of Virginia twin study). Am J Cardiol 1991;68:661-8.
33. Diamond JA, Phillips RA. Hypertensive heart disease. Hypertens Res 2005;28:191-202.
34. Dzau VJ. Tissue renin-angiotensin system in myocardial hypertrophy and failure. Arch Intern Med 1993;153:937-42.
35. Barr M, MacKenzie SM, Friel EC, et al. Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency. Hypertension 2007;49:113-9.
36. Gradman AH, Alfayoumi F. From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease. Prog Cardiovasc Dis 2006;48:326-41.
37. Levy D, Garrison RJ, Savage DD, et al. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990;322:1561-6.