Physical activity prevents augmented body fat accretion in moderately iron-deficient rats

Journal of Nutrition

Volumn 138, Issue 7, 2008, Pages 1293-1297

  McClung, James P ^a   Andersen, Nancy E ^a   Tarr, Tyson N ^a   Stahl, Chad H ^b   Young, Andrew J ^a  

^a U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BODY COMPOSITION; BODY FAT; BODY WEIGHT; CONTROLLED STUDY; FOOD INTAKE; IRON DEFICIENCY; IRON INTAKE; IRON STORAGE; LEAN BODY WEIGHT; MALE; NONHUMAN; PHYSICAL ACTIVITY; RAT; RUNNING; SPRAGUE DAWLEY RAT; ADIPOSE TISSUE; ANIMAL; ANIMAL MODEL; BIOLOGICAL MODEL; BLOOD; BONE DENSITY; EATING; GLUCOSE BLOOD LEVEL; HISTOLOGY; HUMAN; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY;

ANIMALIA; RATTUS;

INSULIN; IRON;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; BODY WEIGHT; BONE DENSITY; EATING; HUMANS; INSULIN; IRON; IRON, DIETARY; MALE; MODELS, ANIMAL; MODELS, BIOLOGICAL; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; RUNNING;

EID: 46249117028     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/138.7.1293     Document Type: Article

References (35)

1. DeMaeyer E, Adiels-Tegman M. The prevalence of anemia in the world. World Health Stat Q. 1985;38:302-16.
2. Looker AC, Cogswell ME, Gunter MT. Iron deficiency: United States, 1999-2000. MMWR Morb Mortal Wkly Rep. 2002;51:897-9.
3. Heath AL, Fairweather-Tait SJ, Clinical implications of changes in the modern diet: iron intake, absorption, and status. Best Pract Res Clin Haematol. 2002;15:225-41.
4. Dallman PR. Biochemical basis for the manifestations of iron deficiency. Annu Rev Nutr. 1986;6:13-40.
5. Beard JL. Iron biology in immune function, muscle metabolism, and neuronal functioning. J Nutr. 2001;131:S568-80.
6. Haas JD, Brownlie T. Iron deficiency and reduced work capacity: a critical review of the research to determine a causal relationship. J Nutr. 2001;131:S676-90.
7. Harris MM, Houtkooper LB, Stanford VA, Parkhill C, Weber JL, Flint-Wagner H, Weiss L, Going SB, Lohman TG. Dietary iron is associated with bone mineral density in healthy postmenopausal women. J Nutr. 2003;133:3598-602.
8. Wenzel BJ, Stults HB, Mayer J. Hypoferraemia in obese adolescents. Lancet. 1962;2:327-8.
9. Pinhas-Hamiel O, Newfield RS, Koren I, Agmon A, Lilos P, Phillip M. Greater prevalence of iron deficiency in overweight and obese children and adolescents. Int J Obes Relat Metab Disord. 2003;27:416-8.
10. Nead KG, Halterman JS, Kaczorowski JM, Auinger P, Weitzman M. Overweight children and adolescents: a risk group for iron deficiency. Pediatrics. 2004;114:104-8.
11. Lecube A, Carrera A, Losada E, Hernandez C, Simo R, Mesa J. Iron deficiency in obese postmenopausal women. Obesity (Silver Spring). 2006;14:1724-30.
12. Chambers EC, Heshka S, Gallagher D, Wang J, Pi-Sunyer FX, Pierson RN Jr. Serum iron and body fat distribution in a multiethnic cohort of adults living in New York City. J Am Diet Assoc. 2006;106:680-4.
13. Medeiros DM, Ilich J, Ireton J, Matkovic V, Shiry L, Wildman R. Femurs from rats fed diets deficient in copper or iron have decreased mechanical strength and altered mineral composition. J Trace Elem Exp Med. 1997;10:197-203.
14. Medeiros DM, Plattner A, Jennings D, Stoecker B. Bone morphology, strength and density are compromised in iron-deficient rats and exacerbated by calcium restriction. J Nutr. 2002; 132:3135-41.
15. Katsumata S, Tsuboi R, Uehara M, Suzuki K. Dietary iron deficiency decreases serum osteocalcin concentration and bone mineral density in rats. Biosci Biotechnol Biochem. 2006;70:2547-50.
16. Parelman M, Stoecker B, Baker A, Medeiros D. Iron restriction negatively affects bone in female rats and mineralization of hFOB osteoblast cells. Exp Biol Med. 2006;231:378-86.
17. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 2002;288:1723-7.
18. Reeves PG, Nielson FH, Fahey JC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123:1939-51.
19. Bianco-Centurion CA, Shiromani PJ. Beneficial effects of regular exercise on sleep in old F344 rats. Neurobiol Aging. 2006;27:1859-69.
20. McClung JP, Stahl CH, Marchitelli LJ, Morales-Martinez N, Mackin KM, Young AJ, Scrimgeour AG. Effects of dietary phytase on body weight gain, body composition and bone strength in growing rats fed a low-zinc diet. J Nutr Biochem. 2006; 17:190-6.
21. Medeiros DM, Stoecker B, Plattner A, Jennings D, Haub M. Iron deficiency negatively affects vertebrae and femurs of rats independently of energy intake and body weight. J Nutr. 2004;134:3061-7.
22. Griffin MG, Kimble R, Hopfer W, Pacifici R. Dual-energy x-ray absorptiometry of the rat: accuracy, precision, and measurement of bone loss. J Bone Miner Res. 1993;8:795-800.
23. Tobin BW, Beard JL, Kenney WL, Exercise training alters feed efficiency and body composition in iron deficient rats. Med Sci Sports Exerc. 1993;25:52-9.
24. Tobin BW, Beard JL. Interactions of iron deficiency and exercise training relative to tissue norepinephrine turnover, triiodothyronine production and metabolic rate in rats. J Nutr. 1990;120:900-8.
25. Ross KL, Eisenstein RS. Iron deficiency decreases mitochondrial aconitase abundance and citrate concentration without affecting tricar-boxylic acid cycle capacity in rat liver. J Nutr. 2002;132:643-51.
26. Zhang S-J, Sandstrom ME, Lanner JT, Thorell A, Westerblad H, Katz A. Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress. Am J Physiol Cell Physiol. 2007;293:C1154-9.
27. Choi JW, Kim SK. Association of serum insulin-like growth factor-1 and erythropoeisis in relation to body iron status. Ann din Lab Sci. 2004;34:324-8.
28. LaMonte MJ, Blair SN. Physical activity, cardiorespiratory fitness, and adiposity: contributions to disease risk. Curr Opin Clin Nutr Metab Care. 2006;9:540-6.
29. Ashenden MJ, Martin DT, Dobson GP, Mackintosh C, Hahn AG. Serum ferritin and anemia in trained female athletes. Int J Sport Nutr. 1998;8:223-9.
30. Beard J, Tobin B. Iron status and exercise. Am J Clin Nutr. 2000; 72:S594-7.
31. McClung JP, Marchitelli LJ, Friedl KE, Young AJ. Prevalence of iron deficiency and iron deficiency anemia among three populations of female military personnel in the US Army. J Am Coll Nutr. 2006;25: 64-9.
32. Solomons NW. Competitive interaction of iron and zinc in the diet: consequences for human nutrition. J Nutr. 1986;116:927-35.
33. Fairweather-Tait SJ. Iron-zinc and calcium-Fe interactions in relation to Zn and Fe absorption. Proc Nutr Soc. 1995;54:465-73.
34. Bodiga S, Krishnapallai MN, Concurrent repletion of iron and zinc reduces intestinal oxidative damage in iron- and zinc-deficient rats. World J Gastroenterol. 2007;13:5707-17.
35. Campos MS, Barrionuevo M, Alferez MJM, Gomez-Ayala AE, Rodriguez-Matas MC, Lopez Aliaga I, Lisbona F. Interactions among iron, calcium, phosphorous and magnesium in the nutritionally iron-deficient rat. Exp Physiol. 1998;83:771-81.