Gonadotropin-releasing hormone (GnRH) and GnRH receptor in bladder cancer epithelia and GnRH effect on bladder cancer cell proliferation

Urologia Internationalis

Volumn 80, Issue 4, 2008, Pages 431-438

  Bahk, Jong Yoon ^a   Kim, Myeong Ok ^b   Park, Moon Seok ^b   Lee, Hae Young ^b   Lee, Jeong Hee ^a   Chung, Bong Chul ^c   Min, Seung Ki ^d  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Gyeongsang National University   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

^d National Police Hospital   (South Korea)

Author keywords

Bladder cancer; GnRH receptor; Gonadotropin releasing hormone; Human bladder epithelia

Indexed keywords

GONADORELIN; GONADORELIN RECEPTOR; MESSENGER RNA;

ARTICLE; BLADDER CANCER; BLADDER EPITHELIUM; CANCER CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; FLOW CYTOMETRY; HEMOCYTOMETER; HUMAN; HUMAN CELL; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MEASUREMENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RIBONUCLEASE PROTECTION ASSAY; SERUM;

CELL PROLIFERATION; EPITHELIAL CELLS; GENE EXPRESSION; GONADOTROPIN-RELEASING HORMONE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; PROBABILITY; RECEPTORS, LHRH; REFERENCE VALUES; RNA, MESSENGER; RNA, NEOPLASM; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 46249111602     PISSN: 00421138     EISSN: None     Source Type: Journal    
DOI: 10.1159/000132703     Document Type: Article

References (31)

1. Morisue K, Yamanaka N, Eto H, Kamidonu S, Nishimura R: Ectopic production of HCG beta by bladder carcinoma in vitro and in vivo. Nippon Hinyokika Gakkai Zasshi 1996;87:643-649.
2. Moreville M, Fritz RW, Mulholland SG: Enhancement of the bladder defense mechanism by an exogenous agent. J Urol 1993;130:607-609.
3. Vaidyanathan S, McCreavy DT, McDicken IW, Soni BM, Mansour P, Wlodarski B, Carron JA, Fraser WD, Singh G, Sett P, Gallagher JA: Immunohistochemical study of parathyroid hormone-related protein in vesical transitional epithelium of patients with spinal cord injury. Spinal Cord 1999;37:760-764.
4. Ponglowhapan S, Church DB, Scaramuzzi RJ, Khalid M: Luteinizing hormone and follicle-stimulating hormone receptors and their transcribed genes (mRNA) are present in the lower urinary tract of intact male and female dogs. Theriogenology 2007;67:353-366.
5. Reichler IM, Barth A, Piche CA, Jochle W, Roos M, Hubler M, Arnold S: Urodynamic parameters and plasma LH/FSH in spayed beagle bitches before and 8 weeks after GnRH depot analogue treatment. Theriogenology 2006;66:2127-2136.
6. Welle MM, Reichler IM, Barth A, Forster U, Sattler U, Arnold S: Immunohistochemical localization and quantitative assessment of GnRH-, FSH-, and LH-receptor mRNA expression in canine skin: a powerful tool to study the pathogenesis of side effects after spaying. Histochem Cell Biol 2006;126:527-535.
7. Hotakainen K, Lintula S, Stenman J, Rintala E, Lindell O, Stenman UH: Detection of messenger RNA for the beta-subunit of chorionic gonadotropin in urinary cells from patients with transitional cell carcinoma of the bladder by reverse transcription-polymerase chain reaction. Int J Cancer 1999;84:304-308.
8. Messing EM: Clinical implications of the expression of epidermal growth factor receptors in human transitional cell carcinoma. Cancer Res 1990;50:2530-2537.
9. Ozaki K, Sukata T, Yamamoto S, Uwagawa S, Seki T, Kawasaki H, Yoshitake A, Wanibuchi H, Koide A, Mori Y, Fukushima S: High susceptibility of p53(+/-) knockout mice in N-butyl-N-(4-hydroxybutyl) nitrosamine urinary bladder carcinogenesis and lack of frequent mutation in residual allele. Cancer Res 1998;58:3806-3811.
10. Ruck A, Paulie S: The epidermal growth factor receptor is involved in autocrine growth of human bladder carcinoma cell lines. Anticancer Res 1997;17:1925-1931.
11. Visvanathan KV, Pocock RD, Summerhayes IC: Preferential and novel activation of H-ras in human bladder. Oncogene Res 1988;3:77-86.
12. Silverman AJ, Krey LC: The luteinizing hormone releasing hormone (LHRH) neuronal networks of the guinea pig brain. I. Intra-and extra hypothalamic projections. Brain Res 1978;157:233-246.
13. Naor Z, Clayton RN, Catt KJ: Characterization of gonadotropin-releasing hormone receptors in cultured rat pituitary cells. Endocrinology 1980;107:1144-1152.
14. Gibbons JM, Mitnick M, Chieffo V: In vitro biosynthesis of TSH- and LH-releasing factors by the human placenta. Am J Obstet Gynecol 1975;121:127-131.
15. Bahk JY, Hyun JS, Chung SH, Kim MO, Choi WS: Stage specific identification of the expression of GnRH mRNA and localization of the GnRH receptor in mature rat and adult human testis. J Urol 1995;154:1958-1961.
16. Li SP, Park MS, Bahk JY, Kim MO: Chronic nicotine and smoking exposure decreases GABA(B1) receptor expression in the rat hippocampus. Neurosci Lett 2002;334:135-139.
17. Chai L, Choi WS, Ronnekleiv OK: Maternal cocaine treatment alters dynorphin and enkephalin mRNA expression in brains of fetal rhesus macaques. J Neurosci 1997;17:1112-1121.
18. Kim MO, Lee YK, Choi WS, Kim JH, Hwang SK, Lee BJ, Kang SG, Kim K, Baik SH: Prolonged ethanol intake increases D2 dopamine receptor expression in the rat brain. Mol Cells 1997;7:682-687.
19. Li SP, Park MS, Yoon H, Rhee KH, Bahk JY, Lee JH, Park JS, Kim MO: Differential distribution of GABA(B1) and GABA(B2) receptor mRNAs in the rat brain. Mol Cells 2003;31:40-47.
20. Yamamoto M, Harm SC, Grasser WA, Thiede MA: Parathyroid hormone-related protein in the rat urinary bladder a smooth muscle relaxant produced locally in response to mechanical stretch. Proc Natl Acad Sci USA 1992;89:5326-5330.
21. Grammatico D, Grignon DJ, Eberwein P, Shepherd RR, Hearn SA, Walton JC: Transitional cell carcinoma of the renal pelvis with choriocarcinomatous differentiation. Immunohistochemical and immunoelectron microscopic assessment of human chorionic gonadotropin production by transitional cell carcinoma of the urinary bladder. Cancer 1993;71:1835-1841.
22. Yohimoto Y, Wolfsen AF, Odell WD: Human chorionic gonadotrophin-like substance in nonendocrine tissues of normal subjects. Science 1977;197:575-577.
23. Heyderman E, Chapman DV, Richardson TC, Calvert I, Rosen SW: Human choronic gonadotrophin and human placental lactogen in extragonadal tumors: an immununoperoxidase study of ten non-germ cell neoplasms. Cancer 1985;56:2674-2682.
24. Saez S, Martin PM: Evidence of estrogen receptors in the trigone area of the human urinary bladder. J Steroid Biochem 1981;15:317-320.
25. Bodker A, Balslev E, Iversen HG, Meyhoff HH, Andersson KE: Estrogen receptors in the human male bladder, prostatic urethra and prostate in prostatic cancer and benign prostatic hyperplasia. Scand J Urol Nephrol 1999;33:237-242.
26. Shibata MA, Shirai T, Asakawa E, Hirose M, Fukushima S: Inhibition by dehydroepiandrosterone of butylated hydroxyanisole (BHA) promotion of rat-bladder carcinogenesis and enhancement of BHA-induced forestomach hyperplasia. Int J Cancer 1993;53:819-823.
27. Shirai T, Yamamoto A, Iwasaki S, Tamano S, Masui T: Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl) amine and followed by testosterone propionate with or without high-fat diet. Carcinogenesis 1991;12:2169-2173.
28. Cunha GR, Lung B: The importance of stroma in morphogenesis and functional activity of urogenital epithelium. In Vitro 1979;15:50-71.
29. Huggins CB: The formation of bone under the influence of epithelium of the urinary tract. Clin Orthop 1968;59:7-19.
30. Johnson FR, McMinn MR: Transitional epithelium and osteogenesis. J Anat 1956;90:106-116.
31. Bahk JY, Hyun JS, Lee H, Kim MO, Cho GJ, Lee BH, Choi WS: Expression of GnRH and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells. Urol Res 1998;26:259-264.