Partial atrophy on prostate needle biopsy cores: A morphologic and immunohistochemical study

American Journal of Surgical Pathology

Volumn 32, Issue 6, 2008, Pages 851-857

  Wang, Wenle ^a   Sun, Xinlai ^b   Epstein, Jonathan I ^a,c  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b Lakewood Pathology Associates   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Adenocarcinoma; AMACR; Atrophy; High molecular weight cytokeratin; Immunohistochemistry; P63; Partial atrophy; Prostate

Indexed keywords

2 METHYLACYL COENZYME A RACEMASE; CYTOKERATIN; PROTEIN P63;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE MARKER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PROSTATE BIOPSY; PROSTATE CARCINOMA; ADENOCARCINOMA; ATROPHY; DIFFERENTIAL DIAGNOSIS; MIDDLE AGED; NEEDLE BIOPSY; PATHOLOGY; PROSTATE; PROSTATE TUMOR;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ATROPHY; BIOPSY, NEEDLE; DIAGNOSIS, DIFFERENTIAL; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PROSTATE; PROSTATIC NEOPLASMS;

EID: 46249105575     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31815a0508     Document Type: Article

References (20)

1. Adley BP, Yang XJ. Alpha-methylacyl coenzyme A racemase immunoreactivity in partial atrophy of the prostate. Am J Clin Pathol. 2006;126:849-855.
2. Chan TY, Mikolajczyk SD, Lecksell K, et al. Immunohistochemical staining of prostate cancer with monoclonal antibodies to the precursor of prostate-specific antigen. Urology. 2003;62:177-181.
3. Cheville JC, Bostwick DG. Postatrophic hyperplasia of the prostate. A histologic mimic of prostatic adenocarcinoma. Am J Surg Pathol. 1995;19:1068-1076.
4. Cina SJ, Silberman MA, Kahane H, et al. Diagnosis of Cowper's glands on prostate needle biopsy. Am J Surg Pathol. 1997;21:550-555.
5. De Marzo AM, Platz EA, Epstein JI, et al. A working group classification of focal prostate atrophy lesions. Am J Surg Pathol. 2006;30:1281-1291.
6. Frauenhoffer EE, Ro JY, el-Naggar AK, et al. Clear cell cribriform hyperplasia of the prostate. Immunohistochemical and DNA flow cytometric study. Am J Clin Pathol. 1991;95:446-453.
7. Gardner WA Jr, Culberson DE. Atrophy and proliferation in the young adult prostate. J Urol. 1987;137:53-56.
8. Gaudin PB, Epstein JI. Adenosis of the prostate. Histologic features in needle biopsy specimens. Am J Surg Pathol. 1995;19:737-747.
9. Gaudin PB, Wheeler TM, Epstein JI. Verumontanum mucosal gland hyperplasia in prostatic needle biopsy specimens. A mimic of low grade prostatic adenocarcinoma. Am J Clin Pathol. 1995;104: 620-626.
10. Herawi M, Parwani AV, Irie J, et al. Small glandular proliferations on needle biopsies: most common benign mimickers of prostatic adenocarcinoma sent in for expert second opinion. Am J Surg Pathol. 2005;29:874-880.
11. Jiang Z, Woda BA, Rock KL, et al. P504S: a new molecular marker for the detection of prostate carcinoma. Am J Surg Pathol. 2001; 25:1397-1404.
12. Jiang Z, Wu CL, Woda BA, et al. P504S/alpha-methylacyl-CoA racemase: a useful marker for diagnosis of small foci of prostatic carcinoma on needle biopsy. Am J Surg Pathol. 2002;26:1169-1174.
13. Jones EC, Clement PB, Young RH. Sclerosing adenosis of the prostate gland. A clinicopathological and immunohistochemical study of 11 cases. Am J Surg Pathol. 1991;15:1171-1180.
14. Luo JH, Yu YP, Cieply K, et al. Gene expression analysis of prostate cancers. Mole Carcinog. 2002;33:25-35.
15. Moore R. The evolution and involution of the prostate gland. Am J Pathol. 1936;12:599-624.
16. Oppenheimer JR, Kahane H, Epstein JI. Granulomatous prostatitis on needle biopsy. Arch Path Lab Med. 1997;121:724-729.
17. Oppenheimer JR, Wills ML, Epstein JI. Partial atrophy in prostate needle cores: another diagnostic pitfall for the surgical pathologist. Am J Surg Pathol. 1998;22:440-445.
18. Sebo TJ, Bostwick DG, Farrow GM, et al. prostatic xanthoma: a mimic of prostatic adenocarcinoma. Hum Pathol. 1994;25: 386-389.
19. Young RH. Tumor-like lesions of the prostate gland. Am J Surg Pathol. 1995;104:607-610.
20. Zhou M, Jiang Z, Epstein JI. Expression and diagnostic utility of alpha-methylacyl-CoA-racemase (P504S) in foamy gland and pseudohyperplastic prostate cancer. Am J Surg Pathol. 2003;27: 772-778.