Cortical plasticity: A proposed mechanism by which genomic factors lead to the behavioral and neurological phenotype of autism spectrum and psychotic-spectrum disorders

Behavioral and Brain Sciences

Volumn 31, Issue 3, 2008, Pages 276-277

  Oberman, Lindsay M ^a   Pascual Leone, Alvaro ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ASSOCIATION; AUTISM; BEHAVIOR DISORDER; BRAIN CORTEX; BRAIN FUNCTION; COMPETENCE; CORPUS CALLOSUM; DELUSION; DIAGNOSTIC VALUE; DISEASE SEVERITY; EXTRACHROMOSOMAL INHERITANCE; GENE EXPRESSION; GENETIC PREDISPOSITION; HERITABILITY; HUMAN; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NOTE; PATERNITY; PATHOGENESIS; PENETRANCE; PHENOTYPE; PSYCHOSIS; SOCIAL BEHAVIOR; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 46249088340     PISSN: 0140525X     EISSN: 14691825     Source Type: Journal    
DOI: 10.1017/S0140525X08004378     Document Type: Note

References (6)

1. Hallet, M. (2007) Transcranial magnetic stimulation: A primer. Neuron 55:187-99.
2. Kleim, J. A., Chan, S., Pringle, K. S., Procaccio, V., Jimenez, R. & Cramer, S. C. (2006) BDNF val66met polymorphism is associated with modified experience-dependent plasticity in human motor cortex. Nature Neuroscience 9: 735-37.
3. Moises, H. W., Zoega, T. & Gottesman, I. I. (2002) The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia. BMC Psychiatry 2:8.
4. Palomino, A., Vallejo-Illarramendi, A., González-Pinto, A., Aldama, A., González-Gómez, C., Mosquera, F., González-García, G. & Matute, C. (2006) Decreased levels of plasma BDNF in first-episode schizophrenia and bipolar disorder patients. Schizophrenia Research 86:321-22. [aBC, LMO]
5. Siekmeier, P. J. & Hoffman, R. E. (2002) Enhanced semantic priming in schizophrenia: A computer model based on excessive pruning of local connections in association cortex. British Journal of Psychiatry 180:345-50.
6. Weickert, C. S., Hyde, T. M., Lipska, B. K., Herman, M. M., Weinberger, D. R. & Kleinman, J. E. (2003) Reduced brain-derived neurotrophic factor in prefrontal cortex of patients with schizophrenia. Molecular Psychiatry 8:592-610.