Poor outcomes of chronic active Epstein-Barr virus infection and hemophagocytic lymphohistiocytosis in non-Japanese adult patients

Clinical Infectious Diseases

Volumn 47, Issue 1, 2008, Pages 105-108

  Sonke, Gabe S ^a   Ludwig, Inge ^c   Van Oosten, Hannah ^b   Baars, Joke W ^a   Meijer, Ellen ^d   Kater, Arnon P ^b   De Jong, Daphne ^a  

^a ANTONI VAN LEEUWENHOEK HOSPITAL   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID DERIVATIVE; CYCLOSPORIN; CYCLOSPORIN A; DEXAMETHASONE; ETOPOSIDE; FLUDARABINE; VIRUS ANTIBODY;

ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANAMNESIS; ARTICLE; BONE MARROW BIOPSY; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DRUG MEGADOSE; EPSTEIN BARR VIRUS; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; HUMAN; HUMAN TISSUE; LABORATORY TEST; MALE; OUTCOME ASSESSMENT; PATHOGENESIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS LOAD; BLOOD; FATALITY; MIDDLE AGED; MORTALITY; PATHOLOGY; VIROLOGY;

ADULT; ANTIBODIES, VIRAL; EPSTEIN-BARR VIRUS INFECTIONS; FATAL OUTCOME; HUMANS; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MALE; MIDDLE AGED; VIRAL LOAD;

EID: 46249085761     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/588790     Document Type: Article

References (15)

1. Cohen J. Epstein-Barr virus infection. N Engl J Med 2000; 343:481-92.
2. Kimura H, Hoshino Y, Kanegane H, et al. Clinical and virologic characteristics of chronic active Epstein-Barr virus infection. Blood 2001; 98:280-6.
3. Okano M, Kawa K, Kimura H, et al. Proposed guidelines for diagnosing chronic active Epstein-Barr virus infection. Am J Hematol 2005; 80:64-9.
4. Straus SE. The chronic mononucleosis syndrome. J Infect Dis 1988; 157:405-12.
5. Kasahara Y, Yachie A, Takei K, et al. Differential cellular targets of Epstein-Barr virus (EBV) infection between acute EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection. Blood 2001; 98:1882-8.
6. Okano M, Matsumoto S, Osato T, Sakiyama Y, Thiele GM, Purtilo DT. Severe chronic active Epstein-Barr virus infection syndrome. Clin Microbiol Rev 1991; 4:129-35.
7. Quintanilla-Martinez L, Kumar S, Fend F, et al. Fulminant EBV+ T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome. Blood 2000; 96:443-51.
8. Chiba T, Goto S, Yokosuka O, et al. Fatal chronic active Epstein-Barr virus infection mimicking autoimmune hepatitis. Eur J Gastroenterol Hepatol 2004; 16:225-8.
9. Aydin GB, Akyuz C, Talim B, et al. Extranodal type T/NK-cell lymphoma with an atypical clinical presentation. Pediatric Hematology and Oncology 2007; 24:291-9.
10. Niesters HG, van Esser J, Fries E,Wolthers KC, Cornelissen J, Osterhaus AD. Development of a real-time quantitative assay for detection of Epstein-Barr virus. J Clin Microbiol 2000; 38:712-5.
11. de Pater-Huijsen FL, de Riemer MJ, Reijneke RM, et al. Products from human mast cell line cells enhance the production of interferon-gamma by CD8+ and CD4+ T cells. Immunology 2002; 106:11-9.
12. Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007; 48:124-31.
13. Katano H, Ali M, Patera A, et al. Chronic active Epstein-Barr virus infection associated with mutations in perforin that impair its maturation. Blood 2004; 103:1244-52.
14. Kimura H. Pathogenesis of chronic active Epstein-Barr virus infection: is this an infectious disease, lymphoproliferative disorder, or immunodeficiency? Rev Med Virol 2006; 16:251-61.
15. Joncas J, Monczak Y, Ghibu F, et al. Brief report: killer cell defect and persistent immunological abnormalities in two patients with chronic active Epstein-Barr virus infection. J Med Virol 1989; 28:110-7.