Predictors of ductal closure and intestinal complications in very low birth weight infants treated with indomethacin

Neonatology

Volumn 94, Issue 1, 2008, Pages 45-51

  Madan, Juliette ^a   Fiascone, John ^a   Balasubramanian, Vidhya ^a   Griffith, John ^b   Hagadorn, James I ^c  

^a TUFTS MEDICAL CENTER   (United States)

^b Division of Clinical Care Research   (United States)

^c Farmington   (United States)

Author keywords

Ductus arteriosus, patent; Enterocolitis, necrotizing; Indomethacin; Infant, very low birth weight; Intestinal perforation; Surgical ligation

Indexed keywords

INDOMETACIN; STEROID;

ARTICLE; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; INTESTINE PERFORATION; LIGATION; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; NECROTIZING ENTEROCOLITIS; PATENT DUCTUS ARTERIOSUS; PRIORITY JOURNAL; RISK FACTOR; TREATMENT RESPONSE; UNIVARIATE ANALYSIS; VERY LOW BIRTH WEIGHT;

CARDIOVASCULAR AGENTS; DUCTUS ARTERIOSUS, PATENT; ENTEROCOLITIS, NECROTIZING; FEMALE; HUMANS; INDOMETHACIN; INFANT, LOW BIRTH WEIGHT; INFANT, NEWBORN; INTESTINAL PERFORATION; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 46049121016     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000113058     Document Type: Article

References (31)

1. Malviya M, Ohlsson A, Shah S: Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants. Cochrane Database of Systematic Reviews 2003;3:CD003951.
2. Gersony WM, Peckham GJ, Ellison RC, Miettinen OS, Nadas AS: Effects of indomethacin in premature infants with PDA: results of a national collaborative study. J Pediatr 1983;102:895-906.
3. Narayanan M, Cooper B, Weiss H, Clyman RI: Prophylactic indomethacin: factors determining permanent ductus arteriosus closure. J Pediatr 2000;136:330-337.
4. Palder SB, Schwartz MZ, Tyson KR, Marr CC: Management of PDA: comparison of operative vs. pharmacologic treatment. J Pediatr Surg 1987;22:1171-1174.
5. Weiss H, Cooper B, Brook M, Schlueter M, Clyman R: Factors determining reopening of the ductus arteriosus after successful clinical closure with indomethacin. J Pediatr 1995;127:466-471.
6. Itabashi K, Ohno T, Nishida H: Indomethacin responsiveness of patent ductus arteriosus and renal abnormalities in preterm infants treated with indomethacin. J Pediatr 2003;143:203-207.
7. Grosfeld JL, Chaet M, Molinari F, Engle W, Engum SA, West KW, et al: Increased risk of NEC in premature infants with PDA treated with indomethacin. Ann Surg 1996;224:350-355.
8. Fuji AM, Brown E: Neonatal NEC with intestinal perforation in ELBW infants receiving early indomethacin treatment for PDA. J Perinatol 2002;22:535-540.
9. Grosfeld JL, Molinari F, Chaet M, Engum SA, West KW, Rescorla FJ, et al: Gastrointestinal perforation and peritonitis in infants and children. An experience with 179 cases over 10 years. Surgery 1996;120:650-655.
10. Zamir O, Shapira SC, Udassin R, Peleg O, Arad I, Nissen S: Gastrointestinal perforation in the neonatal period. Am J Perinatol 1988;5:131-133.
11. Pumberger W, Mayr M, Kohlhauser C, Weninger M: Spontaneous localized intestinal perforation in VLBW infants. J Am Coll Surg 2002;195:796-803.
12. O'Donovan DJ, Baetiong A, Adams K, Chen A, Smith EO, Adams JM, et al: NEC and gastrointestinal complications after indomethacin therapy and surgical ligation in premature infants with PDA. J Perinatol 2003;23:286-290.
13. Dollberg S, Lusky A, Reichman B: PDA, indomethacin and NEC in VLBW infants: a population-based study. J Pediatr Gastroenterol Nutr 2005;40:184-188.
14. Robie DK, Waltrip T, Garcia-Prats JA, Pokorny WJ, Jaksic T: Is surgical ligation of PDA the preferred initial approach for the neonate with ELBW? J Pediatr Surg 1996;31:1134-1137.
15. Cotton RB, Stahlman MT, Kovar I, Catterton WZ: Medical management of small preterm infants with symptomatic patent ductus arteriosus. J Pediatr 1979;2:467-473.
16. Satur CR, Walker DR, Dickinson DF: Day case ligation of PDA in preterm infants: a 10-year review. Arch Dis Child 1991;66:477-480.
17. Bancalari E, Claure N, Gonzales A: Patent ductus arteriosus and respiratory outcome in premature infants. Biol Neonate 2005;88:192-201.
18. Clyman RI: Mechanisms regulating the ductus arteriosus. Biol Neonate 2006;89:330-335.
19. Bell MJ, Ternberg JL, Keating JP, Marshall R, Barton L, Brotherton T: Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg 1978;187:1-7.
20. Richardson DK, Corcoran JD, Escobar GJ, Lee SK: SNAP-II and SNAPPE-II: simplified newborn illness severity and mortality risk scores. J Pediatr 2001;138:92-100.
21. Koch J, Hensley G, Roy L, Brown S, Ramaciotti Cl, Rosenfeld C: Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1,000 grams or less. Pediatrics 2006;117:1113-1121.
22. Van Overmeire B: Patent ductus arteriosus: How aggressive should we be? Neonatology 2007;91:318.
23. Trus T, Winthrop AL, Pipe S, Shah J, Langer JC, Lau GY: Optimal management of PDA in the neonate weighing less than 800 g. J Pediatr Surg 1993;28:1137-1139.
24. Little DC, Pratt TC, Blalock SE, Krauss DR, Cooney DR, Custer MD: PDA in micropreemies and full term infants: the relative merits of surgical ligation versus indomethacin treatment. J Pediatr Surg 2003;38:492-496.
25. Quinn D, Cooper B, Clyman RI: Factors associated with permanent closure of the ductus arteriosus: a role for prolonged indomethacin therapy. Pediatrics 2002;110:e10.
26. Sperandio M, Beedgen B, Feneberg R, Huppertz C, Brussau J, Poschl J, et al: Effectiveness and side effects of an escalating, stepwise approach to indomethacin treatment for symptomatic PDA in premature infants below 33 weeks of gestation. Pediatrics 2005;116:1361-1366.
27. Jaillard S, Larrue B, Rakza T, Magnenant E, Warembourg H, Storme L: Consequences of delayed surgical closure of PDA in very premature infants. Ann Thorac Surg 2006;81:231-234.
28. Keller RL, Clyman RI: Persistent Doppler flow predicts lack of response to multiple courses of indomethacin in premature infants with recurrent PDA. Pediatrics 2003;112;583-587.
29. Lee LC, Tillett A, Tulloh R, Yates R, Kelsall W: Outcome following PDA ligation in premature infants: a retrospective cohort analysis. BMC Pediatrics 2006;6:15.
30. Laughon M, Bose C, Clark R: Treatment strategies to prevent or close a PDA in preterm infants and outcomes. J Perinatol 2007;27:164-170.
31. Uauy RD, Fanaroff AA, Korones SB, Phillips EA, Phillips JB, Wright JJ: NEC in VLBW infants: biodemographic and clinical correlates. NICHD Research Network. J Pediatr 1991;119:630-638.