Hydroxyhydroquinone-free coffee: A double-blind, randomized controlled dose-response study of blood pressure

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 18, Issue 6, 2008, Pages 408-414

  Yamaguchi, Tohru ^a   Chikama, Akiro ^a   Mori, Kenta ^a   Watanabe, Takuya ^a   Shioya, Yasushi ^a   Katsuragi, Yoshihisa ^a   Tokimitsu, Ichiro ^a  

^a KAO CORPORATION   (Japan)

Author keywords

Chlorogenic acid; Coffee; Hydroxyhydroquinone; Hypertension; Randomized controlled trial

Indexed keywords

1,2,4 BENZENETRIOL; CHLOROGENIC ACID; HYDROQUINONE DERIVATIVE;

ADULT; AGED; ARTICLE; BLOOD PRESSURE; CHEMISTRY; CLINICAL TRIAL; COFFEE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HUMAN; HYPERTENSION; MALE; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; BLOOD PRESSURE; CHLOROGENIC ACID; COFFEE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROQUINONES; HYPERTENSION; MALE; MIDDLE AGED;

EID: 46049118021     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2007.03.004     Document Type: Article

References (18)

1. Clifford M.N. Chlorogenic acids and other cinnamated-nature, occurrence and dietary burden. J Sci Food Agric 79 (1999) 362-372
2. Olthof M., Hollman P., Buijsman M., van Amelsvoort J., and Katan M. Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans. J Nutr 133 6 (2003) 1806-1814
3. Vita J.A. Polyphenols and cardiovascular disease: effects on endothelial and platelet function. Am J Clin Nutr 81 Suppl. 1 (2005) 292S-297S
4. Watanabe T., Arai Y., Mitsui Y., Kusaura T., Okawa W., Kajihara Y., et al. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clin Exp Hypertens 28 5 (2006) 439-449
5. Suzuki A., Yamamoto N., Jokura H., Yamamoto M., Fujii A., Tokimitsu I., et al. Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats. J Hypertens 24 6 (2006 Jun) 1065-1073
6. Noordzij M., Uiterwaal C., Arends L., Kok F., Grobbee D., and Geleijnse J. Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens 23 5 (2005) 921-928
7. Sudano I., Binggeli C., Spieker L., Lüscher T., Ruschitzka F., Noll G., et al. Cardiovascular effects of coffee: is it a risk factor?. Prog Cardiovasc Nurs 20 2 (2005) 65-69
8. Hamer M. Coffee and health: explaining conflicting results in hypertension. J Hum Hypertens 20 (2006) 909-912
9. Suzuki A., Kagawa D., Ochiai R., Tokimitsu I., and Saito I. Green coffee bean extract and its metabolites have a hypotensive effect in spontaneously hypertensive rats. Hypertens Res 25 1 (2002 Jan) 99-107
10. Kozuma K., Tsuchiya S., Kohori J., Hase T., and Tokimitsu I. Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects. Hypertens Res 28 9 (2005) 711-718
11. Suzuki A., Fujii A., Yamamoto N., Yamamoto M., Ohminami H., Kameyama A., et al. Improvement of hypertension and vascular dysfunction by hydroxyhydroquinone-free coffee in a genetic model of hypertension. FEBS Lett 580 9 (2006) 2317-2322
12. Halliwell B., Long L., Yee T., Lim S., and Kelly R. Establishing biomarkers of oxidative stress: the measurement of hydrogen peroxide in human urine. Curr Med Chem 11 9 (2004) 1085-1092
13. Cai H., and Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 87 10 (2000) 840-844
14. Whitworth J.A. 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens 21 11 (2003 Nov) 1983-1992
15. Ministry of health, labour and welfare of Japan, the national health nutrition survey in Japan, 2004 (2006), Dai-Ichi Shuppan Pub., Tokyo
16. Chobanian A.V., Bakris G.L., Black H.R., Cushman W.C., Green L.A., Izzo J.L., et al. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension 42 6 (2003) 1206-1252
17. Herrmann K. Occurrence and content of hydroxycinnamic and hydroxybenzoic acid compounds in foods. Crit Rev Food Sci Nutr 28 4 (1989) 315-347
18. Chikama A., Yamaguchi T., Watanabe T., Mori K., Katsuragi Y., Tokimitsu I., et al. Effects of chlorogenic acids in hydroxyhydroquinone-reduced coffee on blood pressure and vascular endothelial function in humans. Progr Med 26 7 (2006) 1723-1736