Inhibition of transforming growth factor-β-induced liver fibrosis by a retinoic acid derivative via the suppression of Col 1A2 promoter activity

Biochemical and Biophysical Research Communications

Volumn 373, Issue 2, 2008, Pages 219-223

  Yang, Kun Lin ^a   Chang, Wen Teng ^b   Hung, Kuo Chen ^c   Li, Eric I C ^a   Chuang, Chia Chang ^a  

^a Institute of Clinical Pharmacy and Pharmaceutical Sciences   (Taiwan)

^b CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

Author keywords

Hepatic stellate cells; Hydrodynamics based gene delivery; Liver fibrosis; Smad family; Sp1 binding activity; TGF

Indexed keywords

CALCIUM; PHELLINUS LINTEUS EXTRACT; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; RETINOIC ACID DERIVATIVE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; CALCIUM TRANSPORT; CELL LINE; CELL NUCLEUS; COL 1A2 GENE; COMPLEX FORMATION; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; GENE; GENE TRANSFER; HYDRODYNAMICS; LIVER CELL; LIVER FIBROSIS; MEDICINAL PLANT; MOUSE; NONHUMAN; PHELLINUS LINTEUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; BASE SEQUENCE; CELL NUCLEUS; COLLAGEN; CYCLOHEXANES; CYTOSOL; GENE EXPRESSION; HUMANS; LIVER CIRRHOSIS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PENTANOIC ACIDS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); REACTIVE OXYGEN SPECIES; SMAD PROTEINS; SP1 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRETINOIN;

INONOTUS LINTEUS;

EID: 46049085182     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.05.192     Document Type: Article

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