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1
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45949092641
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TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: Synthesis, physicochemical and pharmacological properties
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Sept 27-30, San Diego, Abst F-332
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Ishikawa, T., Matsunaga, N., Tawada, H. et al. TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: Synthesis, physicochemical and pharmacological properties. 42nd Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Diego) 2002, Abst F-332.
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(2002)
42nd Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Ishikawa, T.1
Matsunaga, N.2
Tawada, H.3
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2
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TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: Synthesis, physicochemical and pharmacological properties
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Ishikawa, T., Matsunaga, N., Tawada, H. et al. TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: Synthesis, physicochemical and pharmacological properties. Bioorg Med Chem 2003, 11(11): 2427-37.
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Ishikawa, T.1
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Hashiguchi, S, Ishikawa, T, Iizawa, Y, Takeda Pharmaceutical Co, Ltd, Phosphonocephem compound. EP 1310502, JP 2002220395, US 2004023943, US 2005176697, US 6906055, WO 0214333
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Hashiguchi, S., Ishikawa, T., Iizawa, Y. (Takeda Pharmaceutical Co., Ltd.). Phosphonocephem compound. EP 1310502, JP 2002220395, US 2004023943, US 2005176697, US 6906055, WO 0214333.
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4
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Hashiguchi, M, Ishikawa, T, Iizawa, Y, Takeda Pharmaceutical Co, Ltd, Phosphonocephem derivatives, their preparation method, and use. JP 11255772, JP 2001048893, US 6417175, WO 9932497
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Hashiguchi, M., Ishikawa, T., Iizawa, Y. (Takeda Pharmaceutical Co., Ltd.). Phosphonocephem derivatives, their preparation method, and use. JP 11255772, JP 2001048893, US 6417175, WO 9932497.
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5
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0037439518
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Bacterial resistance: Origins, epidemiology, and impact
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Livermore, D.M. Bacterial resistance: Origins, epidemiology, and impact. Clin Infect Dis 2003, 36(Suppl. 1): S11-23.
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Clin Infect Dis
, vol.36
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Livermore, D.M.1
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6
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3843081646
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In vitro antimicrobial activity of T-01925, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599
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Iizawa, Y., Nagai, J., Ishikawa, T., Hashiguchi, S., Nakao, M., Miyake, A., Okonogi, K. In vitro antimicrobial activity of T-01925, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599. J Infect Chemother 2004, 10(3): 146-56.
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J Infect Chemother
, vol.10
, Issue.3
, pp. 146-156
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Iizawa, Y.1
Nagai, J.2
Ishikawa, T.3
Hashiguchi, S.4
Nakao, M.5
Miyake, A.6
Okonogi, K.7
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7
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45949106760
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TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: In vitro and in vivo antibacterial activity
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Sept 27-30, San Diego, Abst F-333
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Iizawa, Y., Nagai, J., Ishikawa, T., Hashiguchi, S., Miyake, A., Nakao, M., Okonogi, K. TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: In vitro and in vivo antibacterial activity. 42nd Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Diego) 2002, Abst F-333.
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(2002)
42nd Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Iizawa, Y.1
Nagai, J.2
Ishikawa, T.3
Hashiguchi, S.4
Miyake, A.5
Nakao, M.6
Okonogi, K.7
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8
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23044471735
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Antimicrobial activity and spectrum of PPI-0903M (T-91625), a novel cephalosporin, tested against a worldwide collection of clinical strains
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Sader, H.S., Fritsche, T.R., Kaniga, K., Ge, Y., Jones, R.N. Antimicrobial activity and spectrum of PPI-0903M (T-91625), a novel cephalosporin, tested against a worldwide collection of clinical strains. Antimicrob Agents Chemother 2005, 49(8): 3501-12.
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(2005)
Antimicrob Agents Chemother
, vol.49
, Issue.8
, pp. 3501-3512
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Sader, H.S.1
Fritsche, T.R.2
Kaniga, K.3
Ge, Y.4
Jones, R.N.5
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9
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34547841550
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In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes
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Mushtaq, S., Warner, M., Ge, Y., Kaniga, K., Livermore, D.M. In vitro activity of ceftaroline (PPI-0903M, T-91825) against bacteria with defined resistance mechanisms and phenotypes. J Antimicrob Chemother 2007, 60(2): 300-11.
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(2007)
J Antimicrob Chemother
, vol.60
, Issue.2
, pp. 300-311
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Mushtaq, S.1
Warner, M.2
Ge, Y.3
Kaniga, K.4
Livermore, D.M.5
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10
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45949084247
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In vitro activity of ceftaroline against isolates from patients with complicated skin and skin structure infections (cSSSI)
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ICAAC, Sept 17-20, Chicago, Abst C2-864
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Ge, Y., Thye, D.A., Talbot, G.H. In vitro activity of ceftaroline against isolates from patients with complicated skin and skin structure infections (cSSSI). 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst C2-864.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Ge, Y.1
Thye, D.A.2
Talbot, G.H.3
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11
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45949087950
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Antibacterial activity of PPI-0903 against isolates from patients with complicated urinary tract infections (cUTI), complicated intra-abdominal infections (cIAI), and hospital-acquired pneumonia (HAP)
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ICAAC, Dec 16-19, Washington, D.C, Abst F-1159
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Kaniga, K., Redman, R., Pecoraro, M.L., Friedland, I., Wikler, M., Ge, Y. Antibacterial activity of PPI-0903 against isolates from patients with complicated urinary tract infections (cUTI), complicated intra-abdominal infections (cIAI), and hospital-acquired pneumonia (HAP). 45th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Dec 16-19, Washington, D.C.) 2005, Abst F-1159.
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(2005)
45th Intersci Conf Antimicrob Agents Chemother
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Kaniga, K.1
Redman, R.2
Pecoraro, M.L.3
Friedland, I.4
Wikler, M.5
Ge, Y.6
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12
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55249117415
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The activity of ceftaroline against community-acquired pneumonia (CAP) bloodstream isolates
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ICAAC, Sept 17-20, Chicago, Abst E-281
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Morrissey, I., Curry, J., Ge, Y., Janes, R. The activity of ceftaroline against community-acquired pneumonia (CAP) bloodstream isolates. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst E-281.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Morrissey, I.1
Curry, J.2
Ge, Y.3
Janes, R.4
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13
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29444443515
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Evaluation of PPI-0903M (T91825), a novel cephalosporin: Bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests
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Jones, R.N., Fritsche, T.R., Ge, Y., Kaniga, K., Sader, H.S. Evaluation of PPI-0903M (T91825), a novel cephalosporin: Bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests. J Antimicrob Chemother 2005, 56(6): 1047-52.
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(2005)
J Antimicrob Chemother
, vol.56
, Issue.6
, pp. 1047-1052
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Jones, R.N.1
Fritsche, T.R.2
Ge, Y.3
Kaniga, K.4
Sader, H.S.5
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14
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45949103682
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Evaluation of the bactericidal activity of the novel cephalosporin ceftaroline (PPI-0903M) compared to ceftriaxone against Streptococcus pneumoniae
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Sept 27-30, San Francisco, Abst E-121
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Sader, H.S., Moet, G.J., Fritsche, T.R., Jones, R.N. Evaluation of the bactericidal activity of the novel cephalosporin ceftaroline (PPI-0903M) compared to ceftriaxone against Streptococcus pneumoniae. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst E-121.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Sader, H.S.1
Moet, G.J.2
Fritsche, T.R.3
Jones, R.N.4
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15
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77950810942
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The in vitro activity of ceftaroline in combination with other antibacterial agents
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ICAAC, Sept 17-20, Chicago, Abst E-279
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Schaadt, R., Sweeney, D., Biek, D., Ge, J., Zurenko, G. The in vitro activity of ceftaroline in combination with other antibacterial agents. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst E-279.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Schaadt, R.1
Sweeney, D.2
Biek, D.3
Ge, J.4
Zurenko, G.5
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16
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35948962693
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In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin- intermediate Staphylococcus aureus in a rabbit endocarditis model
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Jacqueline, C., Caillon, J., Le Mabecque, V. et al. In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin- intermediate Staphylococcus aureus in a rabbit endocarditis model. Antimicrob Agents Chemother 2007, 51(9): 3397-400.
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(2007)
Antimicrob Agents Chemother
, vol.51
, Issue.9
, pp. 3397-3400
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Jacqueline, C.1
Caillon, J.2
Le Mabecque, V.3
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17
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45949094062
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In vivo efficacy of ceftaroline (PPI-0903), a new cephalosporin, against methicillin-resistant Staphylococcus aureus (MRSA): Comparison with vancomycin (VAN) and linezolid (LZO) in a rabbit endocarditis model (REM)
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Sept 27-30, San Francisco, Abst B-1819
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Jacqueline, C., Grossi, O., Le Mabecque, V., Bugnon, D., Cailon, J., Ge, Y., Potel, G. In vivo efficacy of ceftaroline (PPI-0903), a new cephalosporin, against methicillin-resistant Staphylococcus aureus (MRSA): Comparison with vancomycin (VAN) and linezolid (LZO) in a rabbit endocarditis model (REM). 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst B-1819.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Jacqueline, C.1
Grossi, O.2
Le Mabecque, V.3
Bugnon, D.4
Cailon, J.5
Ge, Y.6
Potel, G.7
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18
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45949093562
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In vivo assessment of the activity of ceftaroline (CPT), linezolid (LZO) and vancomycin (VAN) in a rabbit osteomyelitis experimental model (OEM) due to MRSA and GISA
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ICAAC, Sept 17-20, Chicago, Abst B-1358
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Jacqueline, C., Caillon, J., Amador, G. et al. In vivo assessment of the activity of ceftaroline (CPT), linezolid (LZO) and vancomycin (VAN) in a rabbit osteomyelitis experimental model (OEM) due to MRSA and GISA. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst B-1358.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Jacqueline, C.1
Caillon, J.2
Amador, G.3
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19
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66149152735
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Real-time evaluation of ceftaroline (CPT), a new cephalosporin vs. vancomycin (VAN) and daptomycin (DAP) in a rat Staphylococcus aureus endocarditis model using in vitro bioluminescent imaging
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ICAAC, Sept 17-20, Chicago, Abst B-819
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Xiong, Y.Q., Li, Y., Abdelsayed, C.A., Biek, D., Bayer, A.S. Real-time evaluation of ceftaroline (CPT), a new cephalosporin vs. vancomycin (VAN) and daptomycin (DAP) in a rat Staphylococcus aureus endocarditis model using in vitro bioluminescent imaging. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst B-819.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Xiong, Y.Q.1
Li, Y.2
Abdelsayed, C.A.3
Biek, D.4
Bayer, A.S.5
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20
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77951267261
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In vitro evaluation of plasma protein binding and metabolic stability of ceftaroline (PPI-0903)
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Sept 27-30, San Francisco, Abst A-1935
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Ge, Y., Hubbel, A. In vitro evaluation of plasma protein binding and metabolic stability of ceftaroline (PPI-0903). 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1935.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Ge, Y.1
Hubbel, A.2
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21
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67149087868
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Penetration of ceftaroline (PPI-0903), a new cephalosporin, into lung tissues: Measurement of plasma and lung tissue concentrations after a short IV infusion in the rabbit
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Sept 27-30, San Francisco, Abst A-1938
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Jacqueline, C., Caillon, J., Miegeville, A., Launay, E., Batard, E., Ge, Y., Potel, G. Penetration of ceftaroline (PPI-0903), a new cephalosporin, into lung tissues: Measurement of plasma and lung tissue concentrations after a short IV infusion in the rabbit. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1938.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Jacqueline, C.1
Caillon, J.2
Miegeville, A.3
Launay, E.4
Batard, E.5
Ge, Y.6
Potel, G.7
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22
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78649457165
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Single-dose pharmacokinetics (PK) of ceftaroline (PPI-0903) in healthy subjects
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Sept 27-30, San Francisco, Abst A-1936
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Ge, Y., Floren, L., Redman, R., Wikler, M., Liao, S. Single-dose pharmacokinetics (PK) of ceftaroline (PPI-0903) in healthy subjects. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1936.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Ge, Y.1
Floren, L.2
Redman, R.3
Wikler, M.4
Liao, S.5
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23
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78649457165
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The pharmacokinetics (PK) and safety of ceftaroline (PPI-0903) in healthy subjects receiving multiple-dose intravenous (IV) infusions
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Sept 27-30, San Francisco, Abst A-1937
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Ge, Y., Redman, R., Floren, L., Liao, S., Wikler, M. The pharmacokinetics (PK) and safety of ceftaroline (PPI-0903) in healthy subjects receiving multiple-dose intravenous (IV) infusions. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1937.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Ge, Y.1
Redman, R.2
Floren, L.3
Liao, S.4
Wikler, M.5
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24
-
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67149087870
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Pharmacokinetics (PK) of ceftaroline (PPI-0903) in subjects with mild or moderate renal impairment (RI)
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Sept 27-30, San Francisco, Abst A-1939
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Ge, Y., Thye, D., Liao, S., Talbot, G. Pharmacokinetics (PK) of ceftaroline (PPI-0903) in subjects with mild or moderate renal impairment (RI). 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1939.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Ge, Y.1
Thye, D.2
Liao, S.3
Talbot, G.4
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25
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45949084247
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Population pharmacokinetics (PK) analysis of ceftaroline (CPT) in volunteers and patients with complicated skin and skin structure infection (cSSSI)
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ICAAC, Sept 17-20, Chicago, Abst A-34
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Ge, Y., Liao, S., Talbot, G.H. Population pharmacokinetics (PK) analysis of ceftaroline (CPT) in volunteers and patients with complicated skin and skin structure infection (cSSSI). 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst A-34.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Ge, Y.1
Liao, S.2
Talbot, G.H.3
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26
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45949109672
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Ceftaroline (CPT) dose adjustment recommendations for subjects with mild or moderate renal impairment (RI)
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ICAAC, Sept 17-20, Chicago, Abst A-35
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Ge, Y., Liao, S., Thye, D.A., Talbot, G.H. Ceftaroline (CPT) dose adjustment recommendations for subjects with mild or moderate renal impairment (RI). 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst A-35.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Ge, Y.1
Liao, S.2
Thye, D.A.3
Talbot, G.H.4
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27
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34948854764
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Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections
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Talbot, G.H., Thye, D., Das, A., Ge, Y. Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections. Antimicrob Agents Chemother 2007, 51(10): 3612-6.
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(2007)
Antimicrob Agents Chemother
, vol.51
, Issue.10
, pp. 3612-3616
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Talbot, G.H.1
Thye, D.2
Das, A.3
Ge, Y.4
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28
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45949083035
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Randomized, observer-blinded, phase 2 study of the efficacy and safety of ceftaroline vs. vancomycin and aztreonam in complicated skin and skin structure infections (cSSSI)
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Sept 27-30, San Francisco, Abst L-1564c
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Thye, D., Ge, Y., Das, A., Talbot, G.H. Randomized, observer-blinded, phase 2 study of the efficacy and safety of ceftaroline vs. vancomycin and aztreonam in complicated skin and skin structure infections (cSSSI). 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst L-1564c.
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(2006)
46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
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Thye, D.1
Ge, Y.2
Das, A.3
Talbot, G.H.4
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33
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45949098387
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In vitro activity of ceftaroline against a collection of recent Gram-positive and Gram- negative U.S. isolates
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ICAAC, Sept 17-20, Chicago, Abst C2-863
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Ge, Y., Biek, D., Sahm, D., Talbot, G.H. In vitro activity of ceftaroline against a collection of recent Gram-positive and Gram- negative U.S. isolates. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst C2-863.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Ge, Y.1
Biek, D.2
Sahm, D.3
Talbot, G.H.4
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34
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45949096083
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In vitro activity of TAK-599, a new anti-MRSA cephalosporin, against Gram-positive and Gram-negative clinical isolates
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May 23-27, New Orleans, Abst A-139
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Ge, Y., Blosser, R.S., Sahm, D.F., Karlowsky, J.A. In vitro activity of TAK-599, a new anti-MRSA cephalosporin, against Gram-positive and Gram-negative clinical isolates. 104th Gen Meet Am Soc Microbiol (ASM) (May 23-27, New Orleans) 2004, Abst A-139.
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(2004)
104th Gen Meet Am Soc Microbiol (ASM)
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Ge, Y.1
Blosser, R.S.2
Sahm, D.F.3
Karlowsky, J.A.4
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35
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40649100228
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Ceftaroline: In vitro potency, spectrum of activity, MIC and disk diffusion breakpoints
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ICAAC, Sept 17-20, Chicago, Abst D-239
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Brown, S.D., Traczewski, M.M. Ceftaroline: In vitro potency, spectrum of activity, MIC and disk diffusion breakpoints. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst D-239.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
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Brown, S.D.1
Traczewski, M.M.2
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36
-
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45949096542
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In vitro activity of cephalosporin PPI-0903M vs. critical resistance types
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ICAAC, Dec 16-19, Washington, D.C, Abst F-1451
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Mushtaq, S., Warner, M., Kaniga, K., Ge, Y., Livermore, D.M. In vitro activity of cephalosporin PPI-0903M vs. critical resistance types. 45th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Dec 16-19, Washington, D.C.) 2005, Abst F-1451.
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(2005)
45th Intersci Conf Antimicrob Agents Chemother
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Mushtaq, S.1
Warner, M.2
Kaniga, K.3
Ge, Y.4
Livermore, D.M.5
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37
-
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25144439510
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Antimicrobial activity and spectrum of PPI-0903 (TAK-599), a novel cephalosporin, tested against a worldwide collection of clinical strains
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ICAAC, Oct 30-Nov 2, Washington, D.C, Abst F-325
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Sader, H.S., Deshpande, L.M., Jones, R.N. Antimicrobial activity and spectrum of PPI-0903 (TAK-599), a novel cephalosporin, tested against a worldwide collection of clinical strains. 44th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Oct 30-Nov 2, Washington, D.C.) 2004, Abst F-325.
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(2004)
44th Intersci Conf Antimicrob Agents Chemother
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Sader, H.S.1
Deshpande, L.M.2
Jones, R.N.3
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38
-
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45949104882
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Evaluation of PPI-0903 (TAK-599), a novel cephalosporin: Bactericidal activity, effects of modifying testing parameters and optimization of disk diffusion tests
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ICAAC, Oct 30-Nov 2, Washington, D.C, Abst F-334
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Sader, H.S., Rhomberg, P.R., Jones, R.N. Evaluation of PPI-0903 (TAK-599), a novel cephalosporin: Bactericidal activity, effects of modifying testing parameters and optimization of disk diffusion tests. 44th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Oct 30-Nov 2, Washington, D.C.) 2004, Abst F-334.
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(2004)
44th Intersci Conf Antimicrob Agents Chemother
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Sader, H.S.1
Rhomberg, P.R.2
Jones, R.N.3
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39
-
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40549135961
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Antimicrobial activity of ME1036 and ceftaroline tested against clinical strains of community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA)
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ICAAC, Sept 17-20, Chicago, Abst E-280
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Sader, H.S., Fritsche, T.R., Jones, R.N. Antimicrobial activity of ME1036 and ceftaroline tested against clinical strains of community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA). 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst E-280.
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(2007)
47th Intersci Conf Antimicrob Agents Chemother
-
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Sader, H.S.1
Fritsche, T.R.2
Jones, R.N.3
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40
-
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45949088079
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Evaluation of the bactericidal activity of ceftaroline (CPT) and ME1036 compared to other beta-lactam agents against cephalosporin-resistant clinical isolates of Streptococcus pneumoniae and R6 mutants with defined resistance genes
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ICAAC, Sept 17-20, Chicago, Abst C2-215
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McGee, L., Biek, D., Ge, Y. et al. Evaluation of the bactericidal activity of ceftaroline (CPT) and ME1036 compared to other beta-lactam agents against cephalosporin-resistant clinical isolates of Streptococcus pneumoniae and R6 mutants with defined resistance genes. 47th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Chicago) 2007, Abst C2-215.
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