Clinical, histologic, and ultrastructural changes after use of human growth factor and cytokine skin cream for the treatment of skin rejuvenation

Journal of Cosmetic and Laser Therapy

Volumn 10, Issue 2, 2008, Pages 104-109

  Hussain, Mussarrat ^a   Phelps, Robert ^b   Goldberg, David J ^a,b  

^a LASER AND SKIN SURGERY CENTER OF NEW YORK   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokine; Growth factor; Skin rejuvenation

Indexed keywords

CELL PROTEIN; CYTOKINE; GROWTH FACTOR;

ADULT; ARTICLE; CELL DENSITY; CLINICAL ASSESSMENT; COLLAGEN SYNTHESIS; CREAM; CUTANEOUS PARAMETERS; DERMIS; EPIDERMIS; FACE; FEMALE; FIBROBLAST; HISTOLOGY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; PHOTOGRAPHY; PRIORITY JOURNAL; PUNCH BIOPSY; REJUVENATION; SELF EVALUATION; SKIN CARE; SKIN CELL; ULTRASTRUCTURE ANALYSIS AND ELECTRON MICROSCOPY; VISUAL ANALOG SCALE; WRINKLE;

ADMINISTRATION, CUTANEOUS; ADULT; AGED; CYTOKINES; FACE; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROSCOPY; MIDDLE AGED; SKIN AGING;

EID: 45849136725     PISSN: 14764172     EISSN: 14764180     Source Type: Journal    
DOI: 10.1080/14764170701885392     Document Type: Article

References (16)

1. Gold MH, Goldman MP, Biron J. Efficacy of novel skin cream containing mixture of human growth factors and cytokines for skin rejuvenation. J Drugs Dermatol. 2007;6:197-201.
2. Gold MH, Goldman MP, Biron J. Human growth factor and cytokine skin cream for facial skin rejuvenation as assessed by 3D in vivo optical skin imaging. J Drugs Dermatol. 2007;6:1018-23.
3. Bullard KM, Longaker MT, Lorenz HP. Fetal wound healing: Current biology. World J Surg. 2003;27:54-61.
4. Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev. 2003;83:835-70.
5. Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: A pilot study. J Cosmet Laser Ther. 2003;4:25-34.
6. Varani J, Dame MK, Rittie L, Fligiel SE, Kang S, Fisher GJ, et al. Decreased collagen production in chronologically aged skin: Roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. Am J Pathol. 2006;168:1861-8.
7. Meigel WN, Gay S, Weber L. Dermal architecture and collagen type distribution. Arch Dermatol Res. 1977;259:1-10.
8. Epstein EH, Munderloh NH. Human skin collagen: Presence of type I and III at all levels of the dermis. J Biol Chem. 1978;253:1336-7.
9. Clark RA. Cutaneous tissue repair: Basic biologic considerations. I. J Am Acad Dermatol. 1985;13:701-25.
10. Schmults CD, Phelps R, Goldberg DJ. Nonablative facial remodeling: Erythema reduction and histologic evidence of new collagen formation using a 300-microsecond 1064-nm Nd:YAG laser. Arch Dermatol. 2004;140:1373-6.
11. Fleischmajer R, Timpl R, Tuderman L, Raisher L, Wiestner M, Perlish JS, et al. Ultrastructural identification of extension aminopropeptides of type I and III collagens in human skin. Proc Natl Acad Sci U S A. 1981;78:7360-4.
12. Kligman AM, Grove GL, Hirose R, Leyden JJ. Topical tretinoin for photoaged skin. J Am Acad Dermatol. 1986;15:836-59.
13. Bhawan J. Short- and long-term histologic effects of topical tretinoin on photodamaged skin. Int J Dermatol. 1998;37:286-92.
14. Neocutis Scientific Newsletter 05, Spring 2006. Accessed September 28, 2007. URL: http://www.neocutis.com/upload/download/SNL05.pdf.
15. Hayes BB, Afshari A, Millecchia L, Willard PA, Povoski SP, Meade BJ. Evaluation of percutaneous penetration of natural rubber latex proteins. Toxicol Sci. 2000;56:262-70.
16. Schaefer H, Lademann J. The role of follicular penetration. A differential view. Skin Pharmacol Appl Skin Physiol. 2001;14 Suppl 1:23-7.