The hydrosoluble fiber Plantago ovata husk improves levodopa (with carbidopa) bioavailability after repeated administration

Journal of the Neurological Sciences

Volumn 271, Issue 1-2, 2008, Pages 15-20

  Diez, M Jose ^a   Garcia, Juan J ^a   Prieto, Carlos ^a   Fernandez, Nelida ^a   Sahagun, Ana ^a   Sierra, Matilde ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

Carbidopa; Levodopa bioavailability; Pharmacokinetics; Plantago ovata husk; Rabbits

Indexed keywords

CARBIDOPA PLUS LEVODOPA; ISPAGULA; PLANTABEN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; CONTROLLED STUDY; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; FRUIT HUSK; NONHUMAN; PLANT FIBER; PLANTAGO OVATA; PRIORITY JOURNAL; REVIEW; TREATMENT DURATION;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CARBIDOPA; DIETARY FIBER; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG COMBINATIONS; LEVODOPA; METABOLIC CLEARANCE RATE; MODELS, ANIMAL; PLANTAGO; RABBITS; TIME FACTORS;

EID: 45849134137     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2008.03.007     Document Type: Review

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