Influence of fumed silicon dioxide on the stabilization of Eudragit® RS/RL 30 D film-coated theophylline pellets

Pharmaceutical Development and Technology

Volumn 13, Issue 3, 2008, Pages 245-253

  Kucera, Shawn A ^a   Stimpel, Doreen ^b   Shah, Navnit H ^c   Malick, A Waseem ^c   Infeld, Martin H ^c   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c HOFFMANN LA ROCHE INC   (United States)

Author keywords

Aeroperl 300; Aerosil 200 VV; Aqueous film coating; Cab O Sil M5 P; Eudragit RL 30 D; Eudragit RS 30 D; Fumed silicon dioxide; Pellets; Physical aging; Stabilization; Theophylline release

Indexed keywords

AEROPERL; AEROSIL; CITRIC ACID TRIETHYL ESTER; DRUG VEHICLE; EUDRAGIT; SILICON DIOXIDE; THEOPHYLLINE;

ARTICLE; CONCENTRATION (PARAMETERS); DISPERSION; DRUG COATING; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; DRUG STORAGE; FILM COATING; FUME; HUMIDITY; MOISTURE; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; VISCOSITY; WATER VAPOR;

ACRYLATES; CHEMISTRY, PHYSICAL; DRUG STABILITY; EXCIPIENTS; LATEX; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PERMEABILITY; POLYMETHACRYLIC ACIDS; POWDERS; SILICON DIOXIDE; TABLETS, ENTERIC-COATED; TENSILE STRENGTH; THEOPHYLLINE; VISCOSITY; WATER;

EID: 45849126130     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450801949665     Document Type: Article

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