Partial compliance with antipsychotic medication is common in patients with schizophrenia

Australian and New Zealand Journal of Psychiatry

Volumn 42, Issue 5, 2008, Pages 382-388

  Rummel Kluge, Christine ^a   Schuster, Tibor ^a   Peters, Stefan ^b   Kissling, Werner ^c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c JANSSEN CILAG GMBH   (Germany)

Author keywords

Adherence; Compliance; Concordance; Partial compliance; Schizophrenia; Survey

Indexed keywords

NEUROLEPTIC AGENT;

ARTICLE; ATTITUDE TO HEALTH; ATTITUDE TO MENTAL ILLNESS; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COGNITIVE DEFECT; DEMOGRAPHY; HOSPITAL READMISSION; HUMAN; MAJOR CLINICAL STUDY; PATIENT ATTITUDE; PATIENT COMPLIANCE; PSYCHOEDUCATION; RELAPSE; RISK FACTOR; SCHIZOPHRENIA; TELECONSULTATION; TREATMENT DURATION;

ANTIPSYCHOTIC AGENTS; GERMANY; HOSPITALIZATION; HUMANS; INTENTION; PATIENT COMPLIANCE; QUESTIONNAIRES; RECURRENCE; RISK FACTORS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 45849120992     PISSN: 00048674     EISSN: 14401614     Source Type: Journal    
DOI: 10.1080/00048670801961107     Document Type: Article

References (49)

1. Byrne, MK, Deane, FP, Lambert, G. and Coombs, T. (2004) Enhancing medication adherence: Clinician outcomes from the Medication Alliance training program. Aust N Z J Psychiatry, 38, pp. 246-253.
2. Puschner, B., Born, A., Giessler, A., Helm, H., Becker, T. and Angermeyer, MC. (2005) [Effects of interventions to improve compliance with antipsychotic medication in people suffering from schizophrenia: results of recent reviews]. Psychiatr Prax, 32, pp. 62-67.
3. Ascher-Svanum, H., Zhu, B., Faries, D., Lacro, JP and Dolder, CR. (2006) A prospective study of risk factors for nonadherence with antipsychotic medication in the treatment of schizophrenia. J Clin Psychiatry, 67, pp. 1114-1123.
4. Kikkert, MJ, Schene, AH and Koeter, MW (2006) Medication adherence in schizophrenia: Exploring patients', carers' and professionals' views. Schizophr Bull, 32, pp. 786-794.
5. Perkins, DO, Johnson, JL and Hamer, RM (2006) Predictors of antipsychotic medication adherence in patients recovering from a first psychotic episode. Schizophr Res, 83, pp. 53-63.
6. Tsang, HW, Fung, KM and Corrigan, PW. (2006) Psychosocial treatment compliance scale for people with psychotic disorders. Aust N Z J Psychiatry, 40, pp. 561-569.
7. Cooper, D., Moisan, J. and Gregoire, JP. (2007) Adherence to atypical antipsychotic treatment among newly treated patients: A population-based study in schizophrenia. J Clin Psychiatry, 68, pp. 818-825.
8. van Dulmen, S., Sluijs, E., van Dijk, L., de Ridder, D., Heerdink, R. and Bensing, J. (2007) Patient adherence to medical treatment: A review of reviews. BMC Health Serv Res, 7, p. 55.
9. Marcus, SC and Olfson, M. (2008) Outpatient antipsychotic treatment and inpatient costs of schizophrenia. Schizophr Bull, 34, pp. 173-180.
10. Woltmann, EM, Valenstein, M. and Welsh, DE (2007) Using pharmacy data on partial adherence to inform clinical care of patients with serious mental illness. Psychiatr Serv, 58, pp. 864-867.
11. Kissling, W. (1994) Compliance, quality assurance and standards for relapse prevention in schizophrenia. Acta Psychiatr Scand Suppl, 382, pp. 16-24.
12. Leucht, S., Barnes, TR, Kissling, W., Engel, RR, Correll, C. and Kane, JM. (2003) Relapse prevention in schizophrenia with new-generation antipsychotics: A systematic review and exploratory meta-analysis of randomized, controlled trials. Am J Psychiatry, 160, pp. 1209-1222.
13. Hogarty, GE and Ulrich, RF. (1977) Temporal effects of drug and placebo in delaying relapse in schizophrenic outpatients. Arch Gen Psychiatry, 34, pp. 297-301.
14. Robinson, DG, Woerner, MG, Alvir, JM, Bilder, RM, Hinrichsen, GA and Lieberman, JA. (2002) Predictors of medication discontinuation by patients with first-episode schizophrenia and schizoaffective disorder. Schizophr Res, 57, pp. 209-219.
15. Giner, J., Canas, F. and Olivares, JM (2006) [Treatment adherence in schizophrenia. A comparison between patient's, relative's and psychiatrist's opinions]. Acta Esp Psiquiatr, 34, pp. 386-392.
16. Velligan, DI, Lam, YW and Glahn, DC (2006) Defining and assessing adherence to oral antipsychotics: A review of the literature. Schizophr Bull, 32, pp. 724-742.
17. Seale, C., Chaplin, R., Lelliott, P. and Quirk, A. (2006) Sharing decisions in consultations involving anti-psychotic medication: A qualitative study of psychiatrists' experiences. Soc Sci Med, 62, pp. 2861-2873.
18. Weiden, PJ, Kozma, C., Grogg, A. and Locklear, J. (2004) Partial compliance and risk of rehospitalization among California Medicaid patients with schizophrenia. Psychiatr Serv, 55, pp. 886-891.
19. Eaddy, M., Grogg, A. and Locklear, J. (2005) Assessment of compliance with antipsychotic treatment and resource utilization in a Medicaid population. Clin Ther, 27, pp. 263-272.
20. Day, JC, Bentall, RP and Roberts, C. (2005) Attitudes toward antipsychotic medication: The impact of clinical variables and relationships with health professionals. Arch Gen Psychiatry, 62, pp. 717-724.
21. Kim, SW, Yoon, JS and Choi, SK. (2006) Survey of medication adherence in patients with schizophrenia: Korean ADHES data. Hum Psychopharmacol, 21, pp. 533-537.
22. Byerly, M., Fisher, R. and Whatley, K. (2005) A comparison of electronic monitoring vs. clinician rating of antipsychotic adherence in outpatients with schizophrenia. Psychiatry Res, 133, pp. 129-133.
23. Schooler, NR. (2003) Relapse and rehospitalization: Comparing oral and depot antipsychotics. J Clin Psychiatry, 64, pp. 14-17.
24. Ayuso-Gutierrez, JL and del Rio Vega, JM. (1997) Factors influencing relapse in the long-term course of schizophrenia. Schizophr Res, 28, pp. 199-206.
25. Weiden, P. and Glazer, W. (1997) Assessment and treatment selection for "revolving door" inpatients with schizophrenia. Psychiatr Q, 68, pp. 377-392.
26. Jeffreys, SE, Harvey, CA, McNaught, AS, Quayle, AS, King, MB and Bird, AS. (1997) The Hampstead Schizophrenia Survey 1991. I: Prevalence and service use comparisons in an inner London health authority, 1986-1991. Br J Psychiatry, 170, pp. 301-306.
27. Leach, LS and Christensen, H. (2006) A systematic review of telephone-based interventions for mental disorders. J Telemed Telecare, 12, pp. 122-129.
28. Velligan, DI, Diamond, PM and Mintz, J. (2007) The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull
29. Burton, SC. (2005) Strategies for improving adherence to second-generation antipsychotics in patients with schizophrenia by increasing ease of use. J Psychiatr Pract, 11, pp. 369-378.
30. Kane, JM. (2006) Review of treatments that can ameliorate nonadherence in patients with schizophrenia. J Clin Psychiatry, 67, pp. 9-14.
31. Lasser, RA, Bossie, CA, Gharabawi, GM and Turner, M. (2004) Patients with schizophrenia previously stabilized on conventional depot antipsychotics experience significant clinical improvements following treatment with long-acting risperidone. Eur Psychiatry, 19, pp. 219-225.
32. Hui, CL, Chen, EY, Kan, CS, Yip, KC, Law, CW and Chiu, CP. (2006) Detection of non-adherent behaviour in early psychosis. Aust N Z J Psychiatry, 40, pp. 446-451.
33. Nasrallah, HA. (2007) The case for long-acting antipsychotic agents in the post-CATIE era. Acta Psychiatr Scand, 115, pp. 260-267.
34. Heres, S., Hamann, J., Kissling, W. and Leucht, S. (2006) Attitudes of psychiatrists toward antipsychotic depot medication. J Clin Psychiatry, 67, pp. 1948-1953.
35. Patel, MX, Nikolaou, V. and David, AS. (2003) Psychiatrists' attitudes to maintenance medication for patients with schizophrenia. Psychol Med, 33, pp. 83-89.
36. Pereira, S. and Pinto, R. (1997) A survey of the attitudes of chronic psychiatric patients living in the community toward their medication. Acta Psychiatr Scand, 95, pp. 464-468.
37. Lindenmayer, JP, Jarboe, K., Bossie, CA, Zhu, Y., Mehnert, A. and Lasser, R. (2005) Minimal injection site pain and high patient satisfaction during treatment with long-acting risperidone. Int Clin Psychopharmacol, 20, pp. 213-221.
38. Pekkala, E. and Merinder, L. (2002) Psychoeducation for schizophrenia. Cochrane Database Syst Rev, 2 Rev 2
39. Pitschel-Walz, G., Leucht, S., Bauml, J., Kissling, W. and Engel, RR. (2001) The effect of family interventions on relapse and rehospitalization in schizophrenia: A meta-analysis. Schizophr Bull, 27, pp. 73-92.
40. Pitschel-Walz, G., Bauml, J., Bender, W., Engel, RR, Wagner, M. and Kissling, W. (2006) Psychoeducation and compliance in the treatment of schizophrenia: Results of the Munich Psychosis Information Project Study. J Clin Psychiatry, 67, pp. 443-452.
41. Olfson, M., Marcus, SC, Wilk, J. and West, JC. (2006) Awareness of illness and nonadherence to antipsychotic medications among persons with schizophrenia. Psychiatr Serv, 57, pp. 205-211.
42. Rummel-Kluge, C., Pitschel-Walz, G. and Kissling, W. (2007) A fast, implementable psychoeducation program for schizophrenia. Psychiatr Serv, 58, p. 1226.
43. Bauml, J., Pitschel-Walz, G., Volz, A., Engel, RR and Kessling, W. (2007) Psychoeducation in schizophrenia: 7-year follow-up concerning rehospitalization and days in hospital in the Munich Psychosis Information Project Study. J Clin Psychiatry, 68, pp. 854-861.
44. Rummel-Kluge, C., Pitschel-Walz, G., Bauml, J. and Kissling, W. (2006) Psychoeducation in schizophrenia: Results of a survey of all psychiatric institutions in Germany, Austria, and Switzerland. Schizophr Bull, 32, pp. 765-775.
45. Dixon, L., Stewart, B., Burland, J., Delahanty, J., Lucksted, A. and Hoffman, M. (2001) Pilot study of the effectiveness of the family-to-family education program. Psychiatr Serv, 52, pp. 965-967.
46. Dixon, L., Lucksted, A. and Stewart, B. (2004) Outcomes of the peer-taught 12-week family-to-family education program for severe mental illness. Acta Psychiatr Scand, 109, pp. 207-215.
47. Rummel, C., Pitschel-Walz, G. and Kissling, W. (2005) [Family members inform family members: Family members as group moderators for psychoeducational groups in schizophrenia]. Psychiatr Prax, 32, pp. 87-92.
48. Rummel, CB, Hansen, WP, Helbig, A., Pitschel-Walz, G. and Kissling, W. (2005) Peer-to-peer psychoeducation in schizophrenia: A new approach. J Clin Psychiatry, 66, pp. 1580-1585.
49. Byerly, MJ, Thompson, A. and Carmody, T. (2007) Validity of electronically monitored medication adherence and conventional adherence measures in schizophrenia. Psychiatr Serv, 58, pp. 844-847.