Anticomplementary activity of triterpenoids from the whole plant of Aceriphyllum rossii against the classical pathway

Planta Medica

Volumn 74, Issue 7, 2008, Pages 726-729

  Min, Byung Sun ^a   Lee, IkSoo ^b   Chang, Min Jung ^a   Jae, Kuk Yoo ^b   Na, MinKyun ^c   Tran, Manh Hung ^b   Phuong, Thien Thuong ^b   Lee, JongPill ^d   Kim, Jung Hee ^e   Jin, Cheol Kim ^f   Mi, Hee Woo ^a   Jae, Sue Choi ^g   Lee, Hyeong Kyu ^e   Bae, KiHwan ^b  

^a Catholic University of Daegu   (South Korea)

^b Chungnam National University   (South Korea)

^c Yeungnam University   (South Korea)

^d Korea Food and Drug Administration   (South Korea)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^f Korea Research Institute of Chemical Technology   (South Korea)

^g Pukyong National University   (South Korea)

Author keywords

Aceriphyllum rossii; Anticomplement activity; Classical pathway; Olean 27 carboxylic acid derivatives; Saxifragaceae

Indexed keywords

23 HYDROXY 3 OXOOLEAN 12 EN 27 OIC ACID; 3 OXOOLEAN 12 EN 27 OIC ACID; 3ALPHA HYDROXYOLEAN 12 EN 27 OIC ACID; 3ALPHA,23 DIACETOXYOLEAN 12 EN 27 OIC ACID; 3ALPHA,23 ISOPROPYLIDENEDIOXYOLEAN 12 EN 27 OIC ACID; ACERIPHYLLIC ACID A; BETA PELTOBOYKINOLIC ACID; CARBOXYL GROUP; KETONE; METHYL GROUP; SUCROSE POLYESTER; TRITERPENOID;

ACERIPHYLLUM ROSSII; ARTICLE; COMPLEMENT CLASSICAL PATHWAY; COMPLEMENT INHIBITION; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG SCREENING; HUMAN; IC 50; MALE; MEDICINAL PLANT; SAXIFRAGACEAE; SERUM; STRUCTURE ACTIVITY RELATION;

COMPLEMENT PATHWAY, CLASSICAL; COMPLEMENT SYSTEM PROTEINS; HUMANS; MALE; OLEANOLIC ACID; PENTACYCLIC TRITERPENES; SAXIFRAGACEAE;

SAXIFRAGACEAE;

EID: 45849086595     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1074534     Document Type: Article

References (18)

1. Kirschfink M. Controlling the complement system in inflammation. Immunopharmacology 1997; 38: 51-62
2. Ember JA, Hugli TE. Complement factors and their receptors. Immunopharmacology 1997; 38: 3-15
3. Lee CB. Illustrated flora of Korea Seoul: Hyangmunsa Co; 1989: 409
4. Han JT, Kim HY, Park YD, Lee YH, Lee KR, Kwon BM et al. Aceriphyllic acid A, a new ACAT inhibitory triterpenoid from Aceriphyllum rossii. Planta Med 2002; 68: 558-61
5. Han JT, Bang MH, Chun OK, Kim DO, Lee CY, Baek NI. Flavonol glycosides from the aerial parts of Aceriphyllum rossii and their antioxidant activities. Arch Pharm Res 2004; 27: 390-5
6. Lee SM, Park JK, Lee YH, Lee CG, Min BS, Kim JH et al. Anti-complementary activity of triterpenoids from fruits of Zizyphus jujuba. Biol Pharm Bull 2004; 27: 1883-6
7. Thuong PT, Min BS, Jin WY, Na MK, Lee JP, Seong RS et al. Anti-complementary activity of ursane-type triterpenoids from Weigela subsessilis. Biol Pharm Bull 2006; 29: 830-3
8. Jung KY, Oh SR, Park SH, Lee IS, Ahn KS, Lee JJ et al. Anti-complement activity of tiliroside from the flower buds of Magnolia fargesii. Biol Pharm Bull 1998; 21: 1077-8
9. Lee IS, Yoo JK, Na MK, Min BS, Lee JP, Yun BS et al. Cytotoxicity of triterpenes isolated from Aceriphyllum rossii. Chem Pharm Bull 2007; 55: 1376-8
10. Min BS, Lee SY, Kim JH, Lee JK, Kim TJ, Kim DH et al. Anti-complement activity of constituents from the stem-bark of Juglans mandshurica. Biol Pharm Bull 2003; 26: 1042-4
11. Oh SR, Kinjo J, Shii Y, Ikeda T, Nohara T, Ahn KS et al. Effects of triterpenoids from Pueraria lobta on immunohemolysis: β-D-glucuronic acid plays an active role in anticomplementary activity in vitro. Planta Med 2000; 66: 506-10
12. Min BS, Gao JJ, Hattori M, Lee HK, Kim YH. Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. Planta Med 2001; 67: 811-4
13. Oh SR, Jung KY, Son KH, Park SH, Lee IS, Ahn KS et al. In vitro anticomplementary activity of hederagenin saponins isolated from roots of Dipsacus asper. Arch Pharm Res 1999; 22: 317-9
14. Sun H, Zhang J, Ye Y, Pan Y, Shen Y. Cytotoxic pentacyclic triterpenoids from the rhizome of Astilbe chinensis. Helv Chim Acta 2003; 86: 2414-23
15. Izawa K, Nagai M, Inoue T. Triterpene acids and bergenin in Peltoboykinia watanabei and Boykinia lycoctonifolia. Phytochemistry 1973; 12: 1508
16. Arisawa M, Bai H, Shimizu S, Koshimura S, Tanaka M, Sasaki T et al. Isolation and identification of a cytotoxic principle from Chrysosplenium grayanum Maxim. (Saxifragaceae) and its antitumor activities. Chem Pharm Bull 1992; 40: 3274-6
17. Chen TK, Ales DC, Baenziger NC, Wiemer DF. Anti-repellent triterpenoids from Cordia allioclova. J Org Chem 1983; 48: 3525-531
18. Dawidar AA, Reisch J, Amer M. Structure of manevalic and azizic acids, two new triterpenes from Cornulaca monacantha Del. Chem Pharm Bull 1979; 27: 2938-42