Microwave-assisted synthesis and anti-HIV activity of new acyclic C-nucleosides of 3-(D-ribo-tetritol-1-yl)-5-mercapto-1,2,4-triazoles. Part 1

Nucleosides, Nucleotides and Nucleic Acids

Volumn 27, Issue 5, 2008, Pages 469-483

  Al Soud, Yaseen A ^a   Al Masoudi, Najim A ^b,d   Schuppler, Thilo ^b   Clercq, Erik De ^c   Pannecouque, Christophe ^c  

^a AL AL BAYT UNIVERSITY   (Jordan)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^d NONE   (Germany)

Author keywords

6 substituted 3 (D ribo tetritol 1 yl) 1,2,4 triazolo 3,4 b 1,3,4 thiadiazoles; Acyclic C nucleosides; Anti HIV activity; Microwave assisted synthesis

Indexed keywords

3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 6 (PHENYLTHIOMETHYL) [1,2,4] TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 6 (THIOPHEN 2 YL) 7H 1,2,4 TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL0 6 ((4 METHOXYPHENYLTHIO)METHYL) [1,2,4] TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 3 (DEXTRO RIBO TETRITOL 1 YL) 6 ((4 METHOXYPHENYLTHIO)METHYL) [1,2,4]TRIAZOLO[3,4 B][1,3,4] THIADIAZOLE; 3 (DEXTRO RIBO TETRITOL 1 YL) 6 (PHENYLTHIO)METHYL) [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (3 AMINOPHENYL) 3 (1',2' O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 7H 1,2,4 TRIAZOLO [3,4 B][1,3,4]THIADIAZOLE; 6 (3 DIMETHYLAMINOPHENYL0 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 7H 1,2,4 TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (3,4 DICHLOROPHENYL) 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 7H 1,2,4 TRIAZOLO [3,4 B][1,3,4]THIADIAZOLE; 6 (4 AMINOPHNEYL) 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 7H 1,2,4 TRIAZOLO [3,4B][1,3,4]THIADIAZOLE; 6 (4 CHLOROPHENYL) 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) [1,2,4]TRIAZOLO [3,4 B][1,3,4]THIADIAZOLE; 6 (ADAMANTAN 1 YL) 3 (1,2 O ISPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 7H 1,2,4 TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (BENZYLTHIOMETHYL) 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL0 [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (BENZYLTHIOMETHYL) 3 (DEXTRO RIBO TETRITOL 1 YL) [1,2,4]TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; 6 (COUMARIN 3 YL) 3 (1,2 O ISOPROPYLIDENE DEXTRO RIBO TETRITOL 1 YL) 7H 1,2,4 TRIAZOLO[3,4 B][1,3,4]THIADIAZOLE; ANTIVIRUS AGENT; TRIAZOLE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; IN VITRO STUDY; VIRUS INHIBITION; VIRUS REPLICATION;

ANTI-HIV AGENTS; DRUG DESIGN; HIV-2; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MICROWAVES; MOLECULAR STRUCTURE; NUCLEOSIDES; TRIAZOLES;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 45849086576     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770802088829     Document Type: Article

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