Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: Role of endogenous prostacyclin and sensory nerves

Journal of Pharmacology and Experimental Therapeutics

Volumn 326, Issue 1, 2008, Pages 105-116

  Brzozowski, Tomasz ^a   Konturek, Peter C ^c   Chlopicki, Stefan ^a   Sliwowski, Zbigniew ^a   Pawlik, Michal ^a   Ptak Belowska, Agata ^a   Kwiecień, Slawomir ^a   Drozdowicz, Danuta ^a   Pajdo, Robert ^a   Slonimska, Ewa ^b   Konturek, Stanislaw J ^a   Pawlik, Wieslaw W ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLNICOTINAMIDE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; ALCOHOL; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CAPSAZEPINE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; MALONALDEHYDE; MESSENGER RNA; PROPIONIC ACID DERIVATIVE; PROSTACYCLIN; PROSTACYCLIN RECEPTOR; PROSTAGLANDIN F1 ALPHA; ROFECOXIB; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG POTENCY; ENZYME ACTIVITY; GENE OVEREXPRESSION; IMMOBILIZATION STRESS; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; STOMACH ACID SECRETION; STOMACH BLOOD FLOW; STOMACH LESION; STOMACH MUCOSA; STOMACH PROTECTION; STOMACH SECRETION; STRESS ULCER; WATER IMMERSION;

ACUTE DISEASE; ANIMALS; EPOPROSTENOL; GASTRIC ACID; GASTRIC MUCOSA; MALE; NEURONS, AFFERENT; NIACINAMIDE; RATS; RATS, WISTAR; STOMACH ULCER; STRESS;

EID: 45749132575     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.136457     Document Type: Article

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