Local Th1/Th2 cytokine expression in experimental murine vaginal candidiasis

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 28, Issue 3, 2008, Pages 352-355

  Ouyang, Weixiang ^a   Chen, Shanjuan ^a   Liu, Zhixiang ^a   Wu, Yan ^a   Li, Jiawen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Candida albicans; Murine model; Th1 Th2 cytokine; Vaginal lavage

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL; ARTICLE; BIOSYNTHESIS; CANDIDA ALBICANS; FEMALE; GENE EXPRESSION REGULATION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MICROBIOLOGY; MOUSE; PATHOLOGY; TH1 CELL; TH2 CELL; VAGINA; VAGINA CANDIDIASIS;

ANIMALS; CANDIDA ALBICANS; CANDIDIASIS, VULVOVAGINAL; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; MICE; MICE, INBRED ICR; TH1 CELLS; TH2 CELLS; TRANSFORMING GROWTH FACTOR BETA1; VAGINA;

EID: 45749122742     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-008-0329-9     Document Type: Article

References (10)

1. Fidel P L Jr, Wolf N A, KuKuruga M A. T lymphocytes in the murine vaginal mucosa are phenotypically distinct from those in the periphery. Infect Immun, 1996,64:3793-3799
2. Fidel P L Jr, Lynch M E, Redondo-Lopez V et al. Systemic cell-mediated immune reactivity in women with recurrent vulvovaginal candidiasis (RVVC). J Infect Dis, 1993,168:1458-1465
3. Fidel P L Jr, Lynch M E, Conaway D H et al. Mice immunized by primary vaginal C. albicans infection develop acquired vaginal mucosal immunity. Infect Immun, 1995,63:547-553
4. Fidel P L Jr, Lynch M E, Sobel J D. Effects of preinduced Candida-specific systemic cell-mediated immunity on experimental vaginal candidiasis. Infect Immun, 1994,62:1032-1038
5. Romani L, Puccet T I P, Bistoni F. Biological role of Th cell subsets in candidiasis. In: Romagnani S, ed. Th1 and Th2 cells in Health and Disease. Farmington, CT: Karger, 1996.114-137
6. Cenci E, Mencacci A, Spaccapelo R et al. T helper cell type 1 (Th1)-and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development. J Infect Dis, 1995,171:1279-1288
7. Macher A M. The pathology of AIDS. Public Health Report, 1988,103:246-254
8. Clift R A. Candidiasis in the transplant patient. Am J Med, 1984,77(Suppl. 4D):34-38
9. Klein R S, Harris C A, Small C B et al. Oral candidiasis in high-risk patients as the initial manifestation of the acquired immunodeficiency syndrome. N Engl J Med, 1984,311:354-357
10. Taylor B N, Saavedra M, Fidel P L. Local Th1/Th2 cytokine production during experimental vaginal candidiasis: potential importance of transforming growth factor-β1. Med Mycol, 2000,38:419-431