Preparation and characterization of infection-resistant antibiotics-releasing hydrogels rods of poly[hydroxyethyl methacrylate-co- poly(ethylene glycol)-methacrylate]: Biomedical application in a novel rabbit penile prosthesis model

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 86, Issue 1, 2008, Pages 18-28

  Arica, M Yakup ^a   Tuǧlu, Devrim ^a   Başar, M Murad ^a   Kiliç, Dilek ^a   Bayramoǧlu, Gülay ^a   Batislam, Ertan ^a  

^a KIRIKKALE UNIVERSITY   (Turkey)

Author keywords

Animal model; Cell adhesion; Drug release; Infection; Polyethylene oxide; polyHEMA; Prosthesis; Protein adsorption

Indexed keywords

ADSORPTION; ANGLE MEASUREMENT; ANTIBIOTICS; BROADBAND AMPLIFIERS; CHEMICALS; COBALT; COBALT COMPOUNDS; COLLOIDS; COMPUTER NETWORKS; CONTACT ANGLE; COPOLYMERIZATION; ETHYLENE; ETHYLENE GLYCOL; GLYCOLS; HEALTH; MICROFLUIDICS; MONOMERS; PHOTOPOLYMERIZATION; PLASTIC PRODUCTS; PLATELETS; POLYETHYLENE GLYCOLS; POLYMERS; PROSTHETICS; STABILIZERS (AGENTS); STAINLESS STEEL; SURFACE PROPERTIES; SURFACES; THERMODYNAMIC STABILITY; WEIGHT CONTROL;

(1 1 0) SURFACE; (ETHYLENE VINYL ALCOHOL) COPOLYMERS; 2 HYDROXYETHYL METHACRYLATE (PHEMA); BIO-MEDICAL APPLICATIONS; BLOOD PROTEIN ADSORPTION; CONTACT-ANGLE MEASUREMENTS; COPOLYMER HYDROGEL; COPOLYMER HYDROGELS; HYDROGEL; HYDROGEL SYSTEMS; HYDROPHILIC SURFACES; INFECTIOUS AGENTS; METHACRYLATE (APMA); PLATELET ADHESIONS; POLY HYDROXY ETHYL METHACRYLATE (PHEMA); POLY(HEMA); POLYETHYLENE GLYCOL (PEG); ROD STRUCTURE; THERMAL STABILITY; TIME PERIODS; TISSUE INFECTIONS; VANCOMYCIN;

HYDROGELS;

2 HYDROXYETHYL METHACRYLATE; CEFTRIAXONE; COPOLYMER; FIBRINOGEN; GENTAMICIN; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN; POLYHYDROXYETHYLMETHACRYLATE CO POLYETHYLENE GLYCOL METHACRYLATE; POLYMACON; VANCOMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DRUG RELEASE; HYDROGEL; HYDROPHILICITY; IMMUNOHISTOCHEMISTRY; LOADING DRUG DOSE; MALE; MATERIAL COATING; MICROBIOLOGICAL EXAMINATION; NONHUMAN; PENIS PROSTHESIS; POLYMERIZATION; PROSTHESIS INFECTION; RABBIT; THERMOSTABILITY; THROMBOCYTE ADHESION; TISSUE SECTION;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL ADHESION; DRUG DELIVERY SYSTEMS; HYDROGEL; HYDROGELS; HYDROGEN-ION CONCENTRATION; MALE; METHACRYLATES; PENILE PROSTHESIS; POLYETHYLENE GLYCOLS; POLYMERS; POLYMETHACRYLIC ACIDS; PROSTHESIS DESIGN; RABBITS;

EID: 45749111347     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.30983     Document Type: Article

References (43)

1. Ruggeri V, Francolini I, Doneli G, Piozzi A. Synthesis, characterization, and in vitro activity of antibiotic releasing polyurethanes to prevent bacterial resistance. J Biomed Mater Res A 2007;81:287-298.
2. De Bartolo L, Morelli S, Bader A, Drioli E. Evaluation of cell behavior related to the physico-chemical properties of polymeric membranes to be used in bioartificial organs. Biomaterials 2002;23:2485-2497.
3. Kwok AY, Qiao GG, Solomon DH. Interpenetrating amphiphilic polymer networks of poly(2-hydroxyethyl methacrylate) and poly(ethylene oxide). Chem Mater 2004;16:5650-5658.
4. Arica MY, Epoxy-derived pHEMA membrane for use bioactive macromolecules immobilization: Covalently bound urease in a continuous model system. J Appl Polym Sci 2000;77:2000-2008.
5. Vidaure A, Cortazar C, Meseguer JS. Water sorption properties of poly(ethyl acrylate-co-hydroxyethyl methacrylate) macroporous hydrogels. Macromol Symp 2003;200:283-290.
6. Larsson A, Ekblad T, Andersson O, Liedberg B. Photografted poly(ethylene oxide) matrix for affinity interaction studies. Biomacromolocules 2007;8:287-295.
7. Abraham S, Brahim S, Ishihara K, Guiseppi-Elie A. Molecularly engineered p(HEMA)-based hydrogels for implant biochip biocompatibility. Biomaterials 2005;26:4767-4778.
8. Long SF, Clarke S, Davies MC, Lewis AL, Hanlon GW, Lloyd AW. Controlled biological response on blends of a phosphorylcholine-based copolymer with poly(butyl methacrylate). Biomaterials 2003;24:4115-4121.
9. Hsiue G-H, Lee S-D, Chang PC-T, Kao C-Y. Surface characterization and biological properties study of silicone rubber membrane grafted with phospholipid as biomaterial via plasma induced graft copolymerization. J Biomed Mater Res 1998;42:134-147.
10. Jenney CR, Anderson JM. Effects of surface-coupled polyethylene oxide on human macrophage adhesion and foreign body giant cell formation in vitro. J Biomed Mater Res 1999;44:206-216.
11. Gursel I, Balcik C, Arica Y, Akkus O, Akkas N, Hasirci V. Synthesis and mechanical properties of interpenetrating networks of polyhydroxybutyrate-co- hydroxyvalerate and polyhydroxyethyl methacrylate. Biomaterials 1998;19:1137-1143.
12. Montheard JP, Chatzopoulos M, Chappard D. 2-Hydroxyethyl methacrylate HEMA; chemical properties and application in biomedical fields. J Macromol Sci Macromol Rev 1992;32:1-34.
13. Bajpai AK. Blood protein adsorption onto macroporous semi- interpenetrating polymer networks (IPNs) of poly(ethylene glycol) PEG) and poly(2-polyhydroxyethyl methacrylate) (PHEMA) and assessment of in vitro blood compatibility. Polym Int 2007;56:231-244.
14. Amiji M, Park K. Prevention of protein adsorption and platelet adhesion on surfaces by PEO/PPO/PEO triblock copolymers. Biomaterials 1992;13:682-692.
15. Arica MY, Bayramoglu G, Arica B, Ito K, Yagci Y. Novel hydrogel membrane based on copoly(hydroxyethyl methacrylate/p-vinylbenzylpoly(ethylene oxide)) for biomedical applications: Properties and drug release characteristics. Macromol Biosci 2005;5:983-992.
16. Stewart PS, Costerton JW. Antibiotic resistance of bacteria in biofilms. Lancet 2001;358:135-138.
17. Silverstein AD, Henry GD, Evans B, Pasmore M, Simmons CJ, Donatucci CF. Biofilm formation on clinically noninfected penile prostheses. J Urol 2009;176:1008-1011.
18. Roberts JA, Fussell EN, Lewis RW. Bacterial adherence to penile prosthesis. Int J Impot Res 1989;1:167-178.
19. Montague DK, Angermeier KW, Lakin MM. Penile prosthesis infection. Int J Impot Res 2001;13:326-328.
20. Raad I, Darouiche R, Hachem R, Mansouri M, Bodey GP. The broad-spectrum activity and efficacy of catheters coated with minocycline and rifampin. J Infect Dis 1996;173:418-424.
21. van Oss CJ. Acid/base interfacial interactions in aqueous media. Colloids Surf A 1993;78:1-49.
22. Bismarck A, Kumru ME, Springer J. Characterization of several polymer surfaces by streaming potential- and wetting measurements: Some reflections on acid-base interactions. J Colloid Surf Sci 1999;217:377-387.
23. Faibish RS, Yoshida W, Cohen Y. Contact angle study on polymer-grafted silicon wafers. J Colloid Surf Sci 2002;256:341-350.
24. van Oss CJ. Long-range and short-range mechanisms of hydrophobic attraction and hydrophilic repulsion in specific and aspecific interactions. J Mol Recognit 2003;16:177-190.
25. Ward R, Anderson J, McVenes R, Stokes K, In vivo biostability of polyether polyurethanes with fluoropolymer and polyethylene oxide surface modifying endgroups; resistance to metal ion oxidation. J Biomed Mater Res A 2007;80:34-44.
26. You Y-Z, Oupicky D. Synthesis of temperature-responsive heterobifunctional block copolymers of poly(ethylene glycol) and poy(N-isopropylacrylamide). Biomacromolecules 2007;8:98-103.
27. Lakshmi S, Jayakrishnan A. Migration resistant, blood-compatible plasticized polyvinyl chloride for medical and related applications. Artif Organs 1998;22:222-229.
28. Ebert M, Ward R, Anderson JM, McVenes R, Stokes K. In vivo biostability of polyether polyurethanes with polyethylene oxide surface modifying endgroups; resistance to biologic oxidation and stress cracking. J Biomed Mater Res A 2005;75:175-184.
29. Lee W-F, Lin W-J. Preparation and gel properties of poly(hydroxyethyl methacrylate-co-poly(ethylene glycol) methacrylate) copolymeric hydrogels by photopolymerization. J Polym Res 2002;9:23-29.
30. Korsmeyer RW, Gurny R, Doelker E, Buri P, Peppas NA. Mechanisms of solute release from porous hydrophilic polymers. Int J Pharm 1983;15:25-35.
31. Ritger PL, Peppas NA. A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J Controlled Release 1987;5:37-42.
32. Siepmann J, Peppas NA. Modeling of drug release from delivery systems based on hydroxpropylmethylcellulose (HPMC). Adv Drug Deliv Rev 2001;48:139-157.
33. Ritger PL, Peppas NA. A simple equation for description of solute release. I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Controlled Release 1987;5:23-36.
34. Bayramoglu G, Arica MY. A novel pH sensitive porous membrane carrier for various biomedical applications based on pHEMA/chitosan: Preparation and its drug release characteristics. Macromol Symp 2003;203:213-218.
35. Nickel JC, Heaton J, Morales A, Costerton JW. Bacterial biofilm in persistent penile prosthesis-associated infection. J Urol 1986;135:586-588.
36. Carson CC. Diagnosis, treatment and prevention of penile prosthesis infection. Int J Impot Res 2003;15:139-146.
37. Carson CC. Financial interest and/or other relationship with American Medical Systems. Bayer, Lilly and Pfizer. Efficacy of antibiotic impregnation of inflatable penile prostheses in decreasing infection in original implants. J Urol 2004;171:1611-1614.
38. Li H, Fairfax MR, Dubocq F, Darouiche RO, Rajpurkar A, Thompson M, Tefilli MV, Dhabuwala CB. Antibacterial activity of antibiotic coated silicone grafts. J Urol 1998;160:1910-1913.
39. Carson CC. Infections in genitourinary prostheses. Urol Clin North Am 1989;16:139-152.
40. Walters FP, Neal DE, Rege AB, George WJ, Ricci MJ, Hellstrom WJ. Cavernous tissue antibiotic levels in penile prosthesis surgery. J Urol 1992;147:1282-1284.
41. Abouassaly R, Montague DK, Angermeier KW. Antibiotic-coated medical devices: With an emphasis on inflatable penile prosthesis. Asian J Androl 2004;6:249-257.
42. Henry GD, Wilson SK, Delk JR, II, Carson CC, Wiygul J, Tornehl C, Cleves MA, Silverstein A, Donatucci CF. Revision washout decreases penile prosthesis infection in revision surgery: a multicenter study. J Urol 2005;173:89-92.
43. Henry GD, Wilson SK, Delk JR, II, Carson CC, Silverstein A, Cleves MA, Donatucci CF. Penile prosthesis cultures during revision surgery: A multicenter study. J Urol 2004;172:153-156.