Steady flow through a realistic human upper airway geometry

International Journal for Numerical Methods in Fluids

Volumn 57, Issue 5, 2008, Pages 631-651

  Nithiarasu, P ^a   Hassan, O ^a   Morgan, K ^a   Weatherill, N P ^a   Fielder, C ^b   Whittet, H ^b   Ebden, P ^b   Lewis, K R ^c  

^a SWANSEA UNIVERSITY   (United Kingdom)

^b SINGLETON HOSPITAL   (United Kingdom)

^c SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

Bioflows; Biomedical modelling; Finite elements; Fluid dynamics; Incompressible flows; Patient specific study; Unstructured meshes

Indexed keywords

GEOMETRY; RESPIRATORY MECHANICS;

AIR FLOWS; COLLAPSE (DRYING); FLOW PASSAGES; FLOW THROUGH; OROPHARYNX; PRESSURE FORCES; QUANTITATIVE SIMULATION; REALISTIC GEOMETRIES; UPPER AIRWAY;

BIOMECHANICS;

EID: 45749106428     PISSN: 02712091     EISSN: 10970363     Source Type: Journal    
DOI: 10.1002/fld.1805     Document Type: Article

References (69)

1. Taylor CA, Hughes TJR, Zarins CK. Finite element modeling of blood flow in arteries. Computer Methods in Applied Mechanics and Engineering 1998; 158:155-196.
2. Calamante F, Yim PJ, Cebral JR. Estimation of bolus dispersion effects in perfusion MRI using image-based computational fluid dynamics. NeuroImage 2003; 19:341-353.
3. Castro MA, Putman CM, Cebral JR. Patient-specific computational modeling of cerebral aneurysms with multiple avenues of flow from 3d rotational angiography images. Academic Radiology 2006; 13:811-821.
4. Cebral JR, Yim PJ, Löhner R, Sato O, Choyke PL. Blood flow modeling in carotis arteries with computational fluid dynamics and MR imaging. Academic Radiology 2002; 9:1286-1299.
5. Kaazempur-Moftad MR, Bathe M, Karcher H, Younis HF, Seong HC, Shim EB, Chan RC, Hinton DP, Isasi AG, Upadhyaya A, Powers MJ, Griffiths LG, Kamm RD. Role of simulation in understanding biological systems. Computers and Structures 2003; 81:715-726.
6. Löhner R, Cebral J, Soto O, Yim P, Burgess JE. Applications of patient-specific CFD in medicine and life sciences. International Journal for Numerical Methods in Fluids 2003; 43:637-650.
7. Milner JS, Moore JA, Rutt BK, Steinman DA. Hemodynamics of human carotid artery bifurcations: computational studies with models reconstructed from magnetic resonance imaging of normal subjects. Journal of Vascular Surgery 1998; 28:143-155.
8. Moreno R, Nicoud F, Rousseau H. Non-linear-transformation field to build moving meshes for patient specific blood flow simulations. In European Conference on Computational Fluid Dynamics, ECCOMAS CFD 2006, Wesseling P, Onate E, Periaus J (eds). TU Delft: The Netherlands, 2006.
9. Steinman DA, Milner JS, Norley CJ, Lownie SP, Holdsworth DW. Image-based computational simulation of flow dynamics in a giant intracranial aneurysm. American Journal of Neuroradiology 2003; 24:559-566.
10. Tabor G, Tame D, Pierron F, Young PG, Watkinson A, Thompson J. Patient specific arterial flow simulation with additional geometric elements. In European Conference on Computational Fluid Dynamics, ECCOMAS CFD 2006, Wesseling P, Onate E, Periaus J (eds). TU Delft: The Netherlands, 2006.
11. Torii R, Oshima. M, Kobayashi T, Takagi K, Tezduyar TE. Computer modelling of cardiovascular fluid-structure interactions with the deforming-spatial-domain/stabilized space-time formulation. Computer Methods in Applied Mechanics and Engineering 2006; 195:1885-1895.
12. Wolters BJBM, Rutten MCM, Schurink GWH, Kose U, de Hart J, van de Vosse FN. A patient-specific computational model of fluid-structure interaction in abdominal aortic aneurysms. Medical Engineering and Physics 2005; 27:871-883.
13. Valencia A, Botto S, Sordo J, Galvez M, Badilla L. Comparison of haemodynamics in vertebral aneurysms of different sizes located in the opthalmic artery. International Journal for Numerical Methods in Fluids 2007; 53:793-809.
14. Mynard JP, Nithiarasu P. A one dimensional arterial blood flow model incorporating ventricular pressure, aortic valve and regional coronary flow using the locally conservative Galerkin (LCG) method. Communications in Numerical Methods in Engineering 2008; DOI: 10.1002/cnm.1117.
15. Ebden P, Jenkins A, Houston G, Davies BH. Comparison of 2 high-dose corticosteroid aerosol treatments, beclomethasone dipropionate (150ug day) and budesonide (1600ug day), for chronic asthma. Thorax 1986; 41:869-874.
16. Hawkins DB, Luxford WM. Laryngeal stenosis from endotracheal intubation - a review of 58 cases. Annals of Otology, Rhinology and Laryngology 1980; 89:454-458.
17. Wright J, Johns R, Watt I, Melville A, Sheldon T. Health effects of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure: a systematic review of the research evidence. British Medical Journal 1997; 314:851-860.
18. Ayappa I, Rapoport DM. The upper airway in sleep: physiology of the pharynx. Physiological Review 2003; 7:9-33.
19. De Boer MF, McCormick LK, Pruyn JFA, Ryckman RM, van den Borne BW. Physical and psychosocial correlates of head and neck cancer: a review of the literature. Otolaryngology - Head and Neck Surgery 1999; 120:427-436.
20. Constantian MB, Clardy RB, The relative importance of septal and nasal valvular surgery in correcting airway obstruction in primary and secondary rhinoplasty. Plastic and Reconstructive Surgery 1996; 98:38-54.
21. Kulish V. Human Respiration. Anatomy and Physiology, Mathematical Modeling, Numerical Simulation and Applications. WIT Press: Southampton, 2006.
22. Cebral JR, Summers RM. Tracheal and central bronchial aerodynamics using virtual bronchoscopy and computational fluid dynamics. IEEE Transactions on Medical Imaging 2004; 23:1021-1033.
23. Takano H, Nishida N, Itoh M, Hyo N, Majima Y. Inhaled particle deposition in unsteady-state respiratory flow at a numerically constructed model of the human larynx. Journal of Aerosol Medicine 2006; 19:314-328.
24. Wall W, Rabczuk T. Fluid-structure interaction in lower airways of ct-based lung geometries. International Journal for Numerical Methods in Fluids 2008; DOI: 10.1002/fld.1763.
25. Ma B, Lutchen KR. An anatomically based hybrid computational model of the human lung and its application to low frequency oscillatory mechanics. Annals of Biomedical Engineering 2006; 34:1691-1704.
26. Jeong S-J, Kim W-S, Sung S-J. Numerical investigation on the flow characteristics and aerodynamic force of the upper airway of patient with sleep apnea using computational fluid dynamics. Medical Engineering and Physics 2007; 29:637-651.
27. Brouns M, Jayaraju ST, Lacor C, De Mey J, Noppen M, Vincken W, Verbanck S. Tracheal stenosis: a flow dynamics study. Journal of Applied Physiology 2007; 102:1178-1184.
28. Jayaraju ST, Brouns M, Verbanck S, Lacor C. Fluid flow and particle deposition analysis in a realistic extrathoracic airway model using unstructured grids. Journal of Aerosol Science 2007; 38:494-508.
29. Nithiarasu P, Liu C-B, Massarotti N. Laminar and turbulent flow through a model human upper airway. Communications in Numerical Methods in Engineering 2007; 23:1057-1069.
30. Wilquem F, Degrez G. Numerical modeling of steady inspiratory airflow through a three-generation model of the human central airways. Journal of Biomechanical Engineering - Transactions of the ASME 1997; 119:59-65.
31. Martonen TB, Zhang ZQ, Yu GQ, Musante CJ. Tliree-dimensional computer modeling of the human upper respiratory tract. Cell Biochemistry and Biophysics 2001; 35:255-261.
32. Zhao Y, Brunskill CT, Lieber BB. Inspiratory and expiratory steady flow analysis in a model symmetrically bifurcating airway. Journal of Biomechanical Engineering - Transactions of the ASME 1997; 119:52-58.
33. Grotberg JB, Jensen OE. Biofluid mechanics in flexible tubes. Annual Reviews of Fluid Mechanics 2004; 36:121-147.
34. Marzo A, Luo XY, Bertram CD. Three-dimensional collapse and steady flow in thick-walled flexible tubes. Journal of Fluids and Structures 2005; 20:817-835.
35. Luo XY, Hinton JS, Liew TT, Tan KK. LES modelling of flow in a simple airway model. Medical Engineering and Physics 2004; 26:403-413.
36. Li W-I, Perzl M, Heyder J, Langer R, Brain JD, Englmeier K-H, Niven RW, Edwards DA. Aerodynamics and aerosol particle deaggregation phenomena in model oral-pharyngeal cavities. Journal of Aerosol Science 1996; 27:1269-1286.
37. Hofmann W. Modeling techniques for inhaled particle deposition: the state of the art. Journal of Aerosol Medicine 1996; 9:369-388.
38. Balashazy I, Heistracher T, Hofmann W. Air flow and particle deposition patterns in bronchial airway bifurcations: the effect of different CFD models and bifurcation geometries. Journal of Aerosol Medicine 1996; 9:287-301.
39. Kaufman JW, Scherer PW, Yang CCG. Predicted combustion product deposition in the human airway. Toxicology 1996; 115:123-128.
40. Li W-I, Edwards DA. Aerosol particle transport and deaggregation phenomena in the mouth and throat. Advanced Drug Delivery Reviews 1997; 26:41-49.
41. Gemci T, Corcoran TE, Yakut K, Shortall B, Chigier N. Spray dynamics and deposition of inhaled medications in the throat. ILASS - Europe 2001, Zurich, September 2-6, 2001.
42. Gemci T, Corcoran TE, Chigier N. A numerical and experimental study of spray dynamics in a simple throat model. Aerosol Science and Technology 2002; 36:18-38.
43. Sheu TWH, Wang SK, Tsai SF. Finite element analysis of particle motion in steady inspiratory airflow. Computer Methods in Applied Mechanics and Engineering 2002; 191:2681-2698.
44. Martonen TB, Zhang Z, Yue G, Musante CJ. 3-D particle transport within the human upper respiratory tract. Journal of Aerosol Science 2002; 33:1095-1110.
45. Hofmann W, Golser R, Balashazy I. Inspiratory deposition efficiency of ultrafine particles in a human airway bifurcation model. Aerosol Science and Technology 2003; 37:988-994.
46. van Ertbruggen C, Hirsch C, Paiva M. Anatomically based three-dimensional model of airways to simulate flow and particle transport using computational fluid dynamics. Journal of Applied Physiology 2005; 98:970-980.
47. Nishino T, Hiraga K. Coordination of swallowing and respiration in unconscious subjects. Journal of Applied Physiology 1991; 70:988-993.
48. Fouke JM, Teeter JP, Strohl KP. Pressure-volume behaviour of the upper airway. Journal of Applied Physiology 1986; 61:912-918.
49. Strohl KP, Fouke JM. Dialating forces on the upper airway of anesthetized dogs. Journal of Applied Physiology 1985; 58:452-458.
50. Verneuil A, Berry DA, Kreiman J, Gerratt BR, Ye M, Berke GS. Modelling measured glottal volume velocity waveforms. Annals of Otology, Rhinology and Laryngology 2003; 112:120-131.
51. Brancatisano T, Collett P, Engel L. Respiratory movements of the vocal cords. Journal of Applied Physiology 1983; 54:1269-1276.
52. Renotte C, Bouffloux V, Wilquem F. Numerical 3d analysis of oscillatory flow in the time-varying laryngeal channel. Journal of Biomechanics 2000; 33:1637-1644.
53. Wang DS, Hassan O, Morgan K, Weatherill NP. Enhanced remeshing from STL files with applications to surface grid generation. Communications in Numerical Methods in Engineering 2007; 23:227-239.
54. Wang DS, Hassan O, Morgan K, Weatherill NP. Eqsm: an efficient high quality surface grid generation method based on remeshing. Computer Methods in Applied Mechanics and Engineering 2006; 195:5621-5633.
55. Wang DS, Hassan O, Morgan K, Weatherill NP. Efficient surface reconstruction from contours based on two-dimensional Delaunay triangulation. International Journal for Numerical Methods in Engineering 2006; 65: 734-751.
56. Spalart PR, Allmaras SR. A one-equation turbulence model for aerodynamic flows. AIAA Paper 92-0439, 1992.
57. Nithiarasu P, Liu C-B. An explicit characteristic based split (CBS) scheme for incompressible turbulent flows. Computer Methods in Applied Mechanics and Engineering 2006; 195:2961-2982.
58. Codina R, Owen H-C, Nithiarasu P, Liu C-B. Numerical comparison of CBS and SGS as stabilization techniques for the incompressible Navier-Stokes equations. International Journal for Numerical Methods in Engineering 2006; 66:1672-1689.
59. Massarotti N, Fausto F, Lewis RW, Nithiarasu P. Explicit and semi-implicit CBS procedures for incompressible viscous flows. International Journal for Numerical Methods in Engineering 2006; 66:1618-1640.
60. Nithiarasu P. An efficient artificial compressibility (AC) scheme based on the characteristic based split (CBS) method for incompressible flows. International Journal for Numerical Methods in Fluids 2003; 56:1815-1845.
61. Nithiarasu P, Mathur JS, Weatherill NP, Morgan K. Three-dimensional incompressible flow calculations using the characteristic based split (CBS) scheme. International Journal for Numerical Methods in Fluids 2004; 44:1207-1229.
62. Zienkiewicz OC, Codina R. A general algorithm for compressible and incompressible flow - part i. The split, characteristic based scheme. International Journal for Numerical Methods in Fluids 1995; 20:869-885.
63. Zienkiewicz OC, Nithiarasu P, Codina R, Vazquez M, Ortiz P. The characteristic-based-split (CBS) procedure: an efficient and accurate algorithm for fluid problems. International Journal for Numerical Methods in Fluids 1999; 31:359-392.
64. Zienkiewicz OC, Taylor RL, Nithiarasu P. The Finite Element Method for Fluid Dynamics. Elsevier Butterworth-Heinemann: Burlinton, MA, 2005.
65. Spalart PR, Jon WH, Strelets M, Allmaras SR. Comments on the feasibility of LES for wings, and on a hybrid RANS/LES approach. Advances in DNS/ LES: First AFOSR International Conference on DNS/LES, Liu C, Liu Z (eds). Greyden: Columbus, OH, 1997.
66. Löhner R, Morgan K, Zienkiewicz OC. The solution of non-linear hyperbolic equation systems by the finite element method. International Journal for Numerical Methods in Fluids 1984; 4:1043-1063.
67. Nithiarasu P, Codina R, Zienkiewicz OC. The characteristic based split (CBS) scheme - a unified approach to fluid dynamics. International Journal for Numerical Methods in Engineering 2006; 66:1514-1546.
68. Heenan AF, Matida E, Pollard A, Finlay WH. Experimental measurements and computational modeling of the flow in an idealized human oropharynx. Experiments in Fluids 2003; 35:70-84.
69. Kleinstreuer C, Zhang Z. Laminar-to-turbulent fluid-particle flows in a human airway model. International Journal of Multiphase Flow 2003; 29:271-289.