Intensity of platelet β3 integrin in patients with hemorrhagic fever with renal syndrome and its correlation with disease severity

Viral Immunology

Volumn 21, Issue 2, 2008, Pages 255-261

  Liu, Zhengwen ^a   Gao, Maicang ^a   Han, Qunying ^a   Fang, Jie ^a   Zhao, Qianzi ^a   Zhang, Ni ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; BETA3 INTEGRIN; CD61 ANTIGEN; CREATININE; UREA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; CONFERENCE PAPER; CONTROL GROUP; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE; HANTAVIRUS; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; THROMBOCYTE COUNT; THROMBOCYTE MEMBRANE; UREA NITROGEN BLOOD LEVEL; VIRUS HEMORRHAGIC FEVER;

ADULT; ALANINE TRANSAMINASE; BLOOD CELL COUNT; BLOOD PLATELETS; BLOOD UREA NITROGEN; CREATININE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE; HANTAAN VIRUS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; INTEGRIN BETA3; MALE; MIDDLE AGED; PLATELET COUNT; RECEPTORS, VIRUS; SERUM ALBUMIN; SEVERITY OF ILLNESS INDEX; STATISTICS AS TOPIC;

HANTAAN VIRUS;

EID: 45749088520     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2007.0098     Document Type: Conference Paper

References (25)

1. Lee HW: Hemorrhagic fever with renal syndrome (HFRS). Scand J Infect Dis 1982;36:S82-S85.
2. Cosgriff TM: Mechanisms of disease in Hantavirus infection: pathophysiology of hemorrhagic fever with renal syndrome. Rev Infect Dis 1991;13:97-107.
3. Schmaljohn C, and Hjelle B: Hantaviruses: a global disease problem. Emerg Infect Dis 1997;3:95-104.
4. Gavrilovskaya IN, Brown EJ, Ginsberg MH, and Mackow ER: Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins. J Virol 1999;73:3951-3959.
5. Mackow ER, and Gavrilovskaya IN: Cellular receptors and hantavirus pathogenesis. Curr Top Microbiol Immunol 2001;256:91-115.
6. Clark RA, Tonnesen MG, Gailit J, and Cheresh DA: Transient functional expression of alphaVbeta 3 on vascular cells during wound repair. Am J Pathol 1996;148:1407-1421.
7. Hodivala-Dilke KM, McHugh KP, Tsakiris DA, et al.: Beta3-integrin- deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J Clin Invest 1999;103:229-238.
8. Reynolds LE, Wyder L, Lively JC, et al.: Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med 2002;8:27-34.
9. Martinez-Lemus LA, Wu X, Wilson E, et al.: Integrins as unique receptors for vascular control. J Vasc Res 2003;40: 211-233.
10. Wu MH: Endothelial focal adhesions and barrier function. J Physiol 2005;569:359-366.
11. Sonnenberg A: Integrin and their ligands. Curr Top Microbiol Immun 1993;184:7-35.
12. Lum H, and Malik AB: Mechanisms of increased endothelial permeability. Can J Physiol Pharmacol 1996;74: 787-800.
13. Stouffer GA, and Smyth SS: Effects of thrombin on interactions between beta3-integrins and extracellular matrix in platelets and vascular cells. Arterioscler Thromb Vasc Biol 2003;23:1971-1978.
14. Liang M, Li D, Xiao SY, Hang C, Rossi CA, and Schmaljohn CS: Antigenic and molecular characterization of hantavirus isolates from China. Virus Res 1994;31:219-233.
15. Lee HW, Lee PW, and Johnson KM: Isolation of the etiologic agent of Korean hemorrhagic fever. J Infect Dis 1978; 137:298-308.
16. Gavrilovskaya IN, Peresleni T, Geimonen E, and Mackow ER: Pathogenic hantaviruses selectively inhibit beta3 integrin directed endothelial cell migration. Arch Virol 2002; 147:1913-1931.
17. Geimonen E, Neff S, Raymond T, Kocer SS, Gavrilovskaya IN, and Mackow ER: Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responses. Proc Natl Acad Sci USA 2002;99:13837-13842.
18. Wehrle-Haller B, and Imhof BA: Integrin-dependent pathologies. J Pathol 2003;200:481-487.
19. Khaiboullina SF, and St Jeor SC: Hantavirus immunology. Viral Immunol 2002;15:609-625.
20. Kim YO, Yoon SA, Ku YM, et al.: Serum albumin level correlates with disease severity in patients with hemorrhagic fever with renal syndrome. J Korean Med Sci 2003; 18:696-700.
21. Jin M, Park J, Lee S, et al.: Hantaan virus enters cells by clathrin-dependent receptor-mediated endocytosis. Virology 2002;294:60-69.
22. Sundstrom JB, McMullan LK, Spiropoulou CF, et al.: Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. J Virol 2001;75: 6070-6085.
23. Mou DL, Wang YP, Huang CX, et al.: Cellular entry of Hantaan virus A9 strain: specific interactions with beta3 integrins and a novel 70kDa protein. Biochem Biophys Res Commun 2006;339:611-617.
24. Song JW, Song KJ, Baek LJ, Frost B, Poncz M, and Park K: In vivo characterization of the integrin beta3 as a receptor for Hantaan virus cellular entry. Exp Mol Med 2005;37:121-127.
25. Larson RS, Brown DC, Ye C, and Hjelle B: Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor. J Virol 2005;79: 7319-2736.