Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP

Acta Crystallographica Section D: Biological Crystallography

Volumn 64, Issue 7, 2008, Pages 745-753

  Young, Paul G ^a   Smith, Clyde A ^b   Metcalf, Peter ^a   Baker, Edward N ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

Author keywords

Cobalt binding; Conformational change; Folate metabolism; Mycobacterium tuberculosis; Nucleotide binding

Indexed keywords

5' ADENYLYL (BETA,GAMMA METHYLENE)DIPHOSPHONATE; 5'-ADENYLYL (BETA,GAMMA-METHYLENE)DIPHOSPHONATE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEIN; CARBAMIC ACID DERIVATIVE; DIVALENT CATION; DRUG DERIVATIVE; FOLYLPOLYGLUTAMATE SYNTHASE; LYSINE; PEPTIDE SYNTHASE;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; MOTION; MYCOBACTERIUM TUBERCULOSIS; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; BINDING SITES; CARBAMATES; CATIONS, DIVALENT; CRYSTALLOGRAPHY, X-RAY; LYSINE; MODELS, MOLECULAR; MOTION; MYCOBACTERIUM TUBERCULOSIS; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, SECONDARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; LACTOBACILLUS CASEI; MYCOBACTERIUM TUBERCULOSIS;

EID: 45749087730     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444908012262     Document Type: Article

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