-
1
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005; 1: 15-25.
-
(2005)
Cell Metab
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
2
-
-
10744230065
-
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
-
Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D. LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr Biol 2003; 13: 2004-2008.
-
(2003)
Curr Biol
, vol.13
, pp. 2004-2008
-
-
Woods, A.1
Johnstone, S.R.2
Dickerson, K.3
Leiper, F.C.4
Fryer, L.G.5
Neumann, D.6
Schlattner, U.7
Wallimann, T.8
Carlson, M.9
Carling, D.10
-
3
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2005; 2: 9-19.
-
(2005)
Cell Metab
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
4
-
-
33847080728
-
AMP-activated protein kinase in metabolic control and insulin signaling
-
Towler MC, Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 2007; 100: 328-341.
-
(2007)
Circ Res
, vol.100
, pp. 328-341
-
-
Towler, M.C.1
Hardie, D.G.2
-
5
-
-
33748747706
-
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
-
Momcilovic M, Hong SP, Carlson M. Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro. J Biol Chem 2006; 281: 25336-25343.
-
(2006)
J Biol Chem
, vol.281
, pp. 25336-25343
-
-
Momcilovic, M.1
Hong, S.P.2
Carlson, M.3
-
6
-
-
33745225026
-
AMP-activated protein kinase-development of the energy sensor concept
-
Hardie DG, Hawley SA, Scott JW. AMP-activated protein kinase-development of the energy sensor concept. J Physiol (Lond) 2006; 574: 7-15.
-
(2006)
J Physiol (Lond)
, vol.574
, pp. 7-15
-
-
Hardie, D.G.1
Hawley, S.A.2
Scott, J.W.3
-
7
-
-
33745654517
-
Expanding role of AMPK in endocrinology
-
Kola B, Boscaro M, Rutter GA, Grossman AB, Korbonits M. Expanding role of AMPK in endocrinology. Trends Endocrinol Metab 2006; 17: 205-215.
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 205-215
-
-
Kola, B.1
Boscaro, M.2
Rutter, G.A.3
Grossman, A.B.4
Korbonits, M.5
-
8
-
-
23744515608
-
Role of hypothalamic 5′-AMP-activated protein kinase in the regulation of food intake and energy homeostasis
-
Kim MS, Lee KU. Role of hypothalamic 5′-AMP-activated protein kinase in the regulation of food intake and energy homeostasis. J Mol Med 2005; 83: 514-520.
-
(2005)
J Mol Med
, vol.83
, pp. 514-520
-
-
Kim, M.S.1
Lee, K.U.2
-
9
-
-
33745204479
-
AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
-
Xue B, Kahn BB. AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol (Lond) 2006; 574: 73-83.
-
(2006)
J Physiol (Lond)
, vol.574
, pp. 73-83
-
-
Xue, B.1
Kahn, B.B.2
-
10
-
-
0033054706
-
Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system
-
Turnley AM, Stapleton D, Mann RJ, Witters LA, Kemp BE, Bartlett PF. Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem 1999; 72: 1707-1716.
-
(1999)
J Neurochem
, vol.72
, pp. 1707-1716
-
-
Turnley, A.M.1
Stapleton, D.2
Mann, R.J.3
Witters, L.A.4
Kemp, B.E.5
Bartlett, P.F.6
-
11
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferre P, Birnbaum MJ, Stuck BJ, Kahn BB. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004; 428: 569-574.
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
Kim, Y.B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
12
-
-
1842582870
-
AMP-activated protein kinase plays a role in the control of food intake
-
Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ. AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 2004; 279: 12005-12008.
-
(2004)
J Biol Chem
, vol.279
, pp. 12005-12008
-
-
Andersson, U.1
Filipsson, K.2
Abbott, C.R.3
Woods, A.4
Smith, K.5
Bloom, S.R.6
Carling, D.7
Small, C.J.8
-
13
-
-
34547651092
-
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
-
Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. J Clin Invest 2007; 117: 2325-2336.
-
(2007)
J Clin Invest
, vol.117
, pp. 2325-2336
-
-
Claret, M.1
Smith, M.A.2
Batterham, R.L.3
Selman, C.4
Choudhury, A.I.5
Fryer, L.G.6
Clements, M.7
Al Qassab, H.8
Heffron, H.9
Xu, A.W.10
Speakman, J.R.11
Barsh, G.S.12
Viollet, B.13
Vaulont, S.14
Ashford, M.L.15
Carling, D.16
Withers, D.J.17
-
14
-
-
3142677140
-
Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase
-
Kim MS, Park JY, Namkoong C, Jang PG, Ryu JW, Song HS, Yun JY, Namgoong IS, Ha J, Park IS, Lee IK, Viollet B, Youn JH, Lee HK, Lee KU. Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med 2004; 10: 727-733.
-
(2004)
Nat Med
, vol.10
, pp. 727-733
-
-
Kim, M.S.1
Park, J.Y.2
Namkoong, C.3
Jang, P.G.4
Ryu, J.W.5
Song, H.S.6
Yun, J.Y.7
Namgoong, I.S.8
Ha, J.9
Park, I.S.10
Lee, I.K.11
Viollet, B.12
Youn, J.H.13
Lee, H.K.14
Lee, K.U.15
-
15
-
-
26244461692
-
Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats
-
Han SM, Namkoong C, Jang PG, Park IS, Hong SW, Katakami H, Chun S, Kim SW, Park JY, Lee KU, Kim MS. Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to hypoglycaemia in rats. Diabetologia 2005; 48: 2170-2178.
-
(2005)
Diabetologia
, vol.48
, pp. 2170-2178
-
-
Han, S.M.1
Namkoong, C.2
Jang, P.G.3
Park, I.S.4
Hong, S.W.5
Katakami, H.6
Chun, S.7
Kim, S.W.8
Park, J.Y.9
Lee, K.U.10
Kim, M.S.11
-
16
-
-
11144242445
-
Role of neuronal energy status in the regulation of adenosine 5′-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior
-
Lee K, Li B, Xi X, Suh Y, Martin RJ. Role of neuronal energy status in the regulation of adenosine 5′-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior. Endocrinology 2005; 146: 3-10.
-
(2005)
Endocrinology
, vol.146
, pp. 3-10
-
-
Lee, K.1
Li, B.2
Xi, X.3
Suh, Y.4
Martin, R.J.5
-
17
-
-
33846432793
-
Metformin inhibits adenosine 5′-monophosphate-activated kinase activation and prevents increases in neuropeptide y expression in cultured hypothalamic neurons
-
Chau-Van C, Gamba M, Salvi R, Gaillard RC, Pralong FP. Metformin inhibits adenosine 5′-monophosphate-activated kinase activation and prevents increases in neuropeptide y expression in cultured hypothalamic neurons. Endocrinology 2007; 148: 507-511.
-
(2007)
Endocrinology
, vol.148
, pp. 507-511
-
-
Chau-Van, C.1
Gamba, M.2
Salvi, R.3
Gaillard, R.C.4
Pralong, F.P.5
-
18
-
-
33745224043
-
Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle
-
Martin TL, Alquier T, Asakura K, Furukawa N, Preitner F, Kahn BB. Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. J Biol Chem 2006; 281: 18933-18941.
-
(2006)
J Biol Chem
, vol.281
, pp. 18933-18941
-
-
Martin, T.L.1
Alquier, T.2
Asakura, K.3
Furukawa, N.4
Preitner, F.5
Kahn, B.B.6
-
19
-
-
33646570554
-
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
-
Watt MJ, Dzamko N, Thomas WG, Rose-John S, Ernst M, Carling D, Kemp BE, Febbraio MA, Steinberg GR. CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. Nat Med 2006; 12: 541-548.
-
(2006)
Nat Med
, vol.12
, pp. 541-548
-
-
Watt, M.J.1
Dzamko, N.2
Thomas, W.G.3
Rose-John, S.4
Ernst, M.5
Carling, D.6
Kemp, B.E.7
Febbraio, M.A.8
Steinberg, G.R.9
-
20
-
-
33746037555
-
Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
-
Steinberg GR, Watt MJ, Fam BC, Proietto J, Andrikopoulos S, Allen AM, Febbraio MA, Kemp BE. Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice. Endocrinology 2006; 147: 3906-3914.
-
(2006)
Endocrinology
, vol.147
, pp. 3906-3914
-
-
Steinberg, G.R.1
Watt, M.J.2
Fam, B.C.3
Proietto, J.4
Andrikopoulos, S.5
Allen, A.M.6
Febbraio, M.A.7
Kemp, B.E.8
-
21
-
-
19944426367
-
Enhanced hypothalamic AMP-activated protein kinase activity contributes to hyperphagia in diabetic rats
-
Namkoong C, Kim MS, Jang PG, Han SM, Park HS, Koh EH, Lee WJ, Kim JY, Park IS, Park JY, Lee KU. Enhanced hypothalamic AMP-activated protein kinase activity contributes to hyperphagia in diabetic rats. Diabetes 2005; 54: 63-68.
-
(2005)
Diabetes
, vol.54
, pp. 63-68
-
-
Namkoong, C.1
Kim, M.S.2
Jang, P.G.3
Han, S.M.4
Park, H.S.5
Koh, E.H.6
Lee, W.J.7
Kim, J.Y.8
Park, I.S.9
Park, J.Y.10
Lee, K.U.11
-
22
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
-
Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Muller C, Carling D, Kahn BB. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002; 415: 339-343.
-
(2002)
Nature
, vol.415
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.B.2
Peroni, O.D.3
Fryer, L.G.4
Muller, C.5
Carling, D.6
Kahn, B.B.7
-
23
-
-
0033638542
-
Development of leptin resistance in rat soleus muscle in response to high-fat diets
-
Steinberg GR, Dyck DJ. Development of leptin resistance in rat soleus muscle in response to high-fat diets. Am J Physiol Endocrinol Metab 2000; 279: E1374-E1382.
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Steinberg, G.R.1
Dyck, D.J.2
-
24
-
-
1842405349
-
Leptin directly alters lipid partitioning in skeletal muscle
-
Muoio DM, Dohm GL, Fiedorek FT, Jr, Tapscott EB, Coleman RA. Leptin directly alters lipid partitioning in skeletal muscle. Diabetes 1997; 46: 1360-1363.
-
(1997)
Diabetes
, vol.46
, pp. 1360-1363
-
-
Muoio, D.M.1
Dohm, G.L.2
Fiedorek, F.T.3
Tapscott, E.B.4
Coleman, R.A.5
-
25
-
-
33845945261
-
Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity
-
Mountjoy PD, Bailey SJ, Rutter GA. Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity. Diabetologia 2007; 50: 168-177.
-
(2007)
Diabetologia
, vol.50
, pp. 168-177
-
-
Mountjoy, P.D.1
Bailey, S.J.2
Rutter, G.A.3
-
27
-
-
21644453934
-
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
-
Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA, Hardie DG, Grossman AB, Korbonits M. Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J Biol Chem 2005; 280: 25196-25201.
-
(2005)
J Biol Chem
, vol.280
, pp. 25196-25201
-
-
Kola, B.1
Hubina, E.2
Tucci, S.A.3
Kirkham, T.C.4
Garcia, E.A.5
Mitchell, S.E.6
Williams, L.M.7
Hawley, S.A.8
Hardie, D.G.9
Grossman, A.B.10
Korbonits, M.11
-
29
-
-
0037382853
-
2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin
-
2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin. Diabetes 2003; 52: 948-956.
-
(2003)
Diabetes
, vol.52
, pp. 948-956
-
-
Kohno, D.1
Gao, H.Z.2
Muroya, S.3
Kikuyama, S.4
Yada, T.5
-
31
-
-
23044437445
-
2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab 2005; 2: 21-33.
-
(2005)
Cell Metab
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
32
-
-
0032936642
-
Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
-
Williams CM, Kirkham TC. Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors. Psychopharmacology (Berl) 1999; 143: 315-317.
-
(1999)
Psychopharmacology (Berl)
, vol.143
, pp. 315-317
-
-
Williams, C.M.1
Kirkham, T.C.2
-
33
-
-
0036361973
-
Reversal of delta 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine
-
Williams CM, Kirkham TC. Reversal of delta 9-THC hyperphagia by SR141716 and naloxone but not dexfenfluramine. Pharmacol Biochem Behav 2002; 71: 333-340.
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 333-340
-
-
Williams, C.M.1
Kirkham, T.C.2
-
34
-
-
32444440208
-
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
-
Pagotto U, Marsicano G, Cota D, Lutz B, Pasquali R. The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 2006; 27: 73-100.
-
(2006)
Endocr Rev
, vol.27
, pp. 73-100
-
-
Pagotto, U.1
Marsicano, G.2
Cota, D.3
Lutz, B.4
Pasquali, R.5
-
35
-
-
0035984946
-
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
-
Kirkham TC, Williams CM, Fezza F, Di Marzo V. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 2002; 136: 550-557.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 550-557
-
-
Kirkham, T.C.1
Williams, C.M.2
Fezza, F.3
Di Marzo, V.4
-
36
-
-
0035848818
-
Leptin-regulated endocannabinoids are involved in maintaining food intake
-
Di Marzo V, Goparaju SK, Wang L, Liu J, Batkai S, Jarai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001; 410: 822-825.
-
(2001)
Nature
, vol.410
, pp. 822-825
-
-
Di Marzo, V.1
Goparaju, S.K.2
Wang, L.3
Liu, J.4
Batkai, S.5
Jarai, Z.6
Fezza, F.7
Miura, G.I.8
Palmiter, R.D.9
Sugiura, T.10
Kunos, G.11
-
37
-
-
45549092924
-
The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system
-
Kola B, Farkas I, Christ-Crain M, Wittmann G, Lolli F, Amin F, Harvey-White J, Liposits Z, Kunos G, Grossman A, Fekete C, Korbonits M. The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system. PLoS ONE. 2008; 3: E1797.
-
(2008)
PLoS ONE
, vol.3
-
-
Kola, B.1
Farkas, I.2
Christ-Crain, M.3
Wittmann, G.4
Lolli, F.5
Amin, F.6
Harvey-White, J.7
Liposits, Z.8
Kunos, G.9
Grossman, A.10
Fekete, C.11
Korbonits, M.12
-
38
-
-
44949151646
-
AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: A novel mechanism in Cushing's syndrome
-
Christ-Crain M, Kola B, Lolli F, Fekete C, Seboek D, Wittmann G, Feltrin D, Igreja SC, Ajodha S, Harvey-White J, Kunos G, Muller B, Pralong F, Aubert G, Arnaldi G, Giacchetti G, Boscaro M, Grossman AB, Korbonits M. AMP-activated protein kinase mediates glucocorticoid-induced metabolic changes: A novel mechanism in Cushing's syndrome.DFASEB J 2008.
-
(2008)
FASEB J
-
-
Christ-Crain, M.1
Kola, B.2
Lolli, F.3
Fekete, C.4
Seboek, D.5
Wittmann, G.6
Feltrin, D.7
Igreja, S.C.8
Ajodha, S.9
Harvey-White, J.10
Kunos, G.11
Muller, B.12
Pralong, F.13
Aubert, G.14
Arnaldi, G.15
Giacchetti, G.16
Boscaro, M.17
Grossman, A.B.18
Korbonits, M.19
-
39
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, Carling D, Kimura S, Nagai R, Kahn BB, Kadowaki T. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8: 1288-1295.
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
40
-
-
0037059013
-
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-coa carboxylase inhibition and AMP-activated protein kinase activation
-
Tomas E, Tsao TS, Saha AK, Murrey HE, Zhang CC, Itani SI, Lodish HF, Ruderman NB. Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation. Proc Natl Acad Sci USA 2002; 99: 16309-16313.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16309-16313
-
-
Tomas, E.1
Tsao, T.S.2
Saha, A.K.3
Murrey, H.E.4
Zhang, C.C.5
Itani, S.I.6
Lodish, H.F.7
Ruderman, N.B.8
-
41
-
-
33645884425
-
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin
-
Andreelli F, Foretz M, Knauf C, Cani PD, Perrin C, Iglesias MA, Pillot B, Bado A, Tronche F, Mithieux G, Vaulont S, Burcelin R, Viollet B. Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology 2006; 147: 2432-2441.
-
(2006)
Endocrinology
, vol.147
, pp. 2432-2441
-
-
Andreelli, F.1
Foretz, M.2
Knauf, C.3
Cani, P.D.4
Perrin, C.5
Iglesias, M.A.6
Pillot, B.7
Bado, A.8
Tronche, F.9
Mithieux, G.10
Vaulont, S.11
Burcelin, R.12
Viollet, B.13
-
42
-
-
34347255023
-
Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake
-
Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T. Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab 2007; 6: 55-68.
-
(2007)
Cell Metab
, vol.6
, pp. 55-68
-
-
Kubota, N.1
Yano, W.2
Kubota, T.3
Yamauchi, T.4
Itoh, S.5
Kumagai, H.6
Kozono, H.7
Takamoto, I.8
Okamoto, S.9
Shiuchi, T.10
Suzuki, R.11
Satoh, H.12
Tsuchida, A.13
Moroi, M.14
Sugi, K.15
Noda, T.16
Ebinuma, H.17
Ueta, Y.18
Kondo, T.19
Araki, E.20
Ezaki, O.21
Nagai, R.22
Tobe, K.23
Terauchi, Y.24
Ueki, K.25
Minokoshi, Y.26
Kadowaki, T.27
more..
-
43
-
-
9144271181
-
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells
-
Zang M, Zuccollo A, Hou X, Nagata D, Walsh K, Herscovitz H, Brecher P, Ruderman NB, Cohen RA. AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. J Biol Chem 2004; 279: 47898-47905.
-
(2004)
J Biol Chem
, vol.279
, pp. 47898-47905
-
-
Zang, M.1
Zuccollo, A.2
Hou, X.3
Nagata, D.4
Walsh, K.5
Herscovitz, H.6
Brecher, P.7
Ruderman, N.B.8
Cohen, R.A.9
-
44
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001; 108: 1167-1174.
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
45
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 2005; 310: 1642-1646.
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.H.4
Bardeesy, N.5
Depinho, R.A.6
Montminy, M.7
Cantley, L.C.8
-
46
-
-
2442631468
-
C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase
-
Kim EK, Miller I, Aja S, Landree LE, Pinn M, McFadden J, Kuhajda FP, Moran TH, Ronnett GV. C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase. J Biol Chem 2004; 279: 19970-19976.
-
(2004)
J Biol Chem
, vol.279
, pp. 19970-19976
-
-
Kim, E.K.1
Miller, I.2
Aja, S.3
Landree, L.E.4
Pinn, M.5
McFadden, J.6
Kuhajda, F.P.7
Moran, T.H.8
Ronnett, G.V.9
-
47
-
-
38349063250
-
Thyroid hormone (T3) rapidly activates p38 and AMPK in skeletal muscle in vivo
-
Irrcher I, Walkinshaw DR, Sheehan TE, Hood DA. Thyroid hormone (T3) rapidly activates p38 and AMPK in skeletal muscle in vivo. J Appl Physiol 2008; 104: 178-185.
-
(2008)
J Appl Physiol
, vol.104
, pp. 178-185
-
-
Irrcher, I.1
Walkinshaw, D.R.2
Sheehan, T.E.3
Hood, D.A.4
-
48
-
-
41649113801
-
Thyroid hormone activates AMP-activated protein kinase via intracellular calcium mobilization and activation of calcium/calmodulin-dependent protein kinase kinase-β
-
Yamauchi M, Kambe F, Cao X, Lu X, Kozaki Y, Oiso Y, Seo H Thyroid hormone activates AMP-activated protein kinase via intracellular calcium mobilization and activation of calcium/calmodulin-dependent protein kinase kinase-β. Mol Endocrinol 2008; 22: 893-903.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 893-903
-
-
Yamauchi, M.1
Kambe, F.2
Cao, X.3
Lu, X.4
Kozaki, Y.5
Oiso, Y.6
Seo, H.7
-
49
-
-
0037323987
-
Long-term regulation of AMP-activated protein kinase and acetyl-CoA carboxylase in skeletal muscle
-
Winder WW, Hardie DG, Mustard KJ, Greenwood LJ, Paxton BE, Park SH, Rubink DS, Taylor EB. Long-term regulation of AMP-activated protein kinase and acetyl-CoA carboxylase in skeletal muscle. Biochem Soc Trans 2003; 31: 182-185.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 182-185
-
-
Winder, W.W.1
Hardie, D.G.2
Mustard, K.J.3
Greenwood, L.J.4
Paxton, B.E.5
Park, S.H.6
Rubink, D.S.7
Taylor, E.B.8
-
50
-
-
45549090446
-
Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated protein kinase activity (AMPK)
-
Ishii T, Hiideki T, Shimizu T, Toshiko K, Sugihara H, Oikawa S, Kamegai J Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated protein kinase activity (AMPK). Proceedings of the 88th Annual Meeting of the Endocrine Society. 2007.
-
(2007)
Proceedings of the 88th Annual Meeting of the Endocrine Society
-
-
Ishii, T.1
Hiideki, T.2
Shimizu, T.3
Toshiko, K.4
Sugihara, H.5
Oikawa, S.6
Kamegai, J.7
-
51
-
-
14644435794
-
Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity
-
Andersson U, Treebak JT, Nielsen JN, Smith KL, Abbott CR, Small CJ, Carling D, Richter EA. Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity. Biochem Biophys Res Commun 2005; 329: 719-725.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 719-725
-
-
Andersson, U.1
Treebak, J.T.2
Nielsen, J.N.3
Smith, K.L.4
Abbott, C.R.5
Small, C.J.6
Carling, D.7
Richter, E.A.8
-
52
-
-
2942748289
-
AMPK activity is diminished in tissues of IL-6 knockout mice: The effect of exercise
-
Kelly M, Keller C, Avilucea PR, Keller P, Luo Z, Xiang X, Giralt M, Hidalgo J, Saha AK, Pedersen BK, Ruderman NB. AMPK activity is diminished in tissues of IL-6 knockout mice: The effect of exercise. Biochem Biophys Res Commun 2004; 320: 449-454.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 449-454
-
-
Kelly, M.1
Keller, C.2
Avilucea, P.R.3
Keller, P.4
Luo, Z.5
Xiang, X.6
Giralt, M.7
Hidalgo, J.8
Saha, A.K.9
Pedersen, B.K.10
Ruderman, N.B.11
-
53
-
-
27844509555
-
Activation of AMPK in rat hypothalamus participates in cold-induced resistance to nutrient-dependent anorexigenic signals
-
Roman EA, Cesquini M, Stoppa GR, Carvalheira JB, Torsoni MA, Velloso LA. Activation of AMPK in rat hypothalamus participates in cold-induced resistance to nutrient-dependent anorexigenic signals. J Physiol (Lond) 2005; 568: 993-1001.
-
(2005)
J Physiol (Lond)
, vol.568
, pp. 993-1001
-
-
Roman, E.A.1
Cesquini, M.2
Stoppa, G.R.3
Carvalheira, J.B.4
Torsoni, M.A.5
Velloso, L.A.6
-
54
-
-
33947357840
-
Glucose regulates AMP-activated protein kinase activity and gene expression in clonal, hypothalamic neurons expressing proopiomelanocortin: Additive effects of leptin or insulin
-
Cai F, Gyulkhandanyan AV, Wheeler MB, Belsham DD. Glucose regulates AMP-activated protein kinase activity and gene expression in clonal, hypothalamic neurons expressing proopiomelanocortin: Additive effects of leptin or insulin. J Endocrinol 2007; 192: 605-614.
-
(2007)
J Endocrinol
, vol.192
, pp. 605-614
-
-
Cai, F.1
Gyulkhandanyan, A.V.2
Wheeler, M.B.3
Belsham, D.D.4
-
55
-
-
31544465941
-
Molecular disruption of hypothalamic nutrient sensing induces obesity
-
He W, Lam TK, Obici S, Rossetti L. Molecular disruption of hypothalamic nutrient sensing induces obesity. Nat Neurosci 2006; 9: 227-233.
-
(2006)
Nat Neurosci
, vol.9
, pp. 227-233
-
-
He, W.1
Lam, T.K.2
Obici, S.3
Rossetti, L.4
-
56
-
-
0038037734
-
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
-
Obici S, Feng Z, Arduini A, Conti R, Rossetti L. Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nat Med 2003; 9: 756-761.
-
(2003)
Nat Med
, vol.9
, pp. 756-761
-
-
Obici, S.1
Feng, Z.2
Arduini, A.3
Conti, R.4
Rossetti, L.5
-
57
-
-
33645531123
-
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats
-
Pocai A, Lam TK, Obici S, Gutierrez-Juarez R, Muse ED, Arduini A, Rossetti L. Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J Clin Invest 2006; 116: 1081-1091.
-
(2006)
J Clin Invest
, vol.116
, pp. 1081-1091
-
-
Pocai, A.1
Lam, T.K.2
Obici, S.3
Gutierrez-Juarez, R.4
Muse, E.D.5
Arduini, A.6
Rossetti, L.7
-
58
-
-
33745362866
-
Critical role of STAT3 in leptin's metabolic actions
-
Buettner C, Pocai A, Muse ED, Etgen AM, Myers MG Jr, Rossetti L. Critical role of STAT3 in leptin's metabolic actions. Cell Metab 2006; 4: 49-60.
-
(2006)
Cell Metab
, vol.4
, pp. 49-60
-
-
Buettner, C.1
Pocai, A.2
Muse, E.D.3
Etgen, A.M.4
Myers, M.G.5
Rossetti, L.6
-
59
-
-
0037456304
-
STAT3 signaling is required for leptin regulation of energy balance but not reproduction
-
Bates SH, Stearns WH, Dundon TA, Schubert M, Tso AW, Wang Y, Banks AS, Lavery HJ, Haq AK, Maratos-Flier E, Neel BG, Schwartz MW, Myers MG Jr. STAT3 signaling is required for leptin regulation of energy balance but not reproduction. Nature 2003; 421: 856-859.
-
(2003)
Nature
, vol.421
, pp. 856-859
-
-
Bates, S.H.1
Stearns, W.H.2
Dundon, T.A.3
Schubert, M.4
Tso, A.W.5
Wang, Y.6
Banks, A.S.7
Lavery, H.J.8
Haq, A.K.9
Maratos-Flier, E.10
Neel, B.G.11
Schwartz, M.W.12
Myers, M.G.13
-
60
-
-
33748742812
-
The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans
-
Steinberg GR, McAinch AJ, Chen MB, O'Brien PE, Dixon JB, Cameron-Smith D, Kemp BE. The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans. J Clin Endocrinol Metab 2006; 91: 3592-3597.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3592-3597
-
-
Steinberg, G.R.1
McAinch, A.J.2
Chen, M.B.3
O'Brien, P.E.4
Dixon, J.B.5
Cameron-Smith, D.6
Kemp, B.E.7
-
61
-
-
33644943620
-
AMPK: A key sensor of fuel and energy status in skeletal muscle
-
Hardie DG, Sakamoto K. AMPK: A key sensor of fuel and energy status in skeletal muscle. Physiology (Bethesda) 2006; 21: 48-60.
-
(2006)
Physiology (Bethesda)
, vol.21
, pp. 48-60
-
-
Hardie, D.G.1
Sakamoto, K.2
-
62
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
Cota D, Proulx K, Smith KA, Kozma SC, Thomas G, Woods SC, Seeley RJ. Hypothalamic mTOR signaling regulates food intake. Science 2006; 312: 927-930.
-
(2006)
Science
, vol.312
, pp. 927-930
-
-
Cota, D.1
Proulx, K.2
Smith, K.A.3
Kozma, S.C.4
Thomas, G.5
Woods, S.C.6
Seeley, R.J.7
-
63
-
-
40749132626
-
Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia
-
McCrimmon RJ, Shaw M, Fan X, Cheng H, Ding Y, Vella MC, Zhou L, McNay EC, Sherwin RS Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia. Diabetes 2008; 57: 444-450.
-
(2008)
Diabetes
, vol.57
, pp. 444-450
-
-
McCrimmon, R.J.1
Shaw, M.2
Fan, X.3
Cheng, H.4
Ding, Y.5
Vella, M.C.6
Zhou, L.7
McNay, E.C.8
Sherwin, R.S.9
-
64
-
-
3242811250
-
Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus
-
McCrimmon RJ, Fan X, Ding Y, Zhu W, Jacob RJ, Sherwin RS. Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus. Diabetes 2004; 53: 1953-1958.
-
(2004)
Diabetes
, vol.53
, pp. 1953-1958
-
-
McCrimmon, R.J.1
Fan, X.2
Ding, Y.3
Zhu, W.4
Jacob, R.J.5
Sherwin, R.S.6
-
65
-
-
33644664033
-
Mechanisms of hypoglycemia-associated autonomic failure and its component syndromes in diabetes
-
Cryer PE. Mechanisms of hypoglycemia-associated autonomic failure and its component syndromes in diabetes. Diabetes 2005; 54: 3592-3601.
-
(2005)
Diabetes
, vol.54
, pp. 3592-3601
-
-
Cryer, P.E.1
-
66
-
-
2442710176
-
Diverse causes of hypoglycemia-associated autonomic failure in diabetes
-
Cryer PE. Diverse causes of hypoglycemia-associated autonomic failure in diabetes. N Engl J Med 2004; 350: 2272-2279.
-
(2004)
N Engl J Med
, vol.350
, pp. 2272-2279
-
-
Cryer, P.E.1
-
67
-
-
33847022735
-
Role of hypothalamic adenosine 5′-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia
-
Alquier T, Kawashima J, Tsuji Y, Kahn BB. Role of hypothalamic adenosine 5′-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia. Endocrinology 2007; 148: 1367-1375.
-
(2007)
Endocrinology
, vol.148
, pp. 1367-1375
-
-
Alquier, T.1
Kawashima, J.2
Tsuji, Y.3
Kahn, B.B.4
-
68
-
-
33748296106
-
Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation
-
McCrimmon RJ, Fan X, Cheng H, McNay E, Chan O, Shaw M, Ding Y, Zhu W, Sherwin RS. Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation. Diabetes 2006; 55: 1755-1760.
-
(2006)
Diabetes
, vol.55
, pp. 1755-1760
-
-
McCrimmon, R.J.1
Fan, X.2
Cheng, H.3
McNay, E.4
Chan, O.5
Shaw, M.6
Ding, Y.7
Zhu, W.8
Sherwin, R.S.9
-
69
-
-
33847746338
-
Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms?
-
Mountjoy PD, Rutter GA. Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms? Exp Physiol 2007; 92: 311-319.
-
(2007)
Exp Physiol
, vol.92
, pp. 311-319
-
-
Mountjoy, P.D.1
Rutter, G.A.2
-
70
-
-
34248204584
-
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: Integration in neuropeptide Y and pro-opio melanocortin networks?
-
Fioramonti X, Contie S, Song Z, Routh VH, Lorsignol A, Penicaud L. Characterization of glucosensing neuron subpopulations in the arcuate nucleus: Integration in neuropeptide Y and pro-opio melanocortin networks? Diabetes 2007; 56: 1219-1227.
-
(2007)
Diabetes
, vol.56
, pp. 1219-1227
-
-
Fioramonti, X.1
Contie, S.2
Song, Z.3
Routh, V.H.4
Lorsignol, A.5
Penicaud, L.6
-
71
-
-
3242765290
-
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides
-
Wang R, Liu X, Hentges ST, Dunn-Meynell AA, Levin BE, Wang W, Routh VH. The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides. Diabetes 2004; 53: 1959-1965.
-
(2004)
Diabetes
, vol.53
, pp. 1959-1965
-
-
Wang, R.1
Liu, X.2
Hentges, S.T.3
Dunn-Meynell, A.A.4
Levin, B.E.5
Wang, W.6
Routh, V.H.7
-
72
-
-
34147139847
-
Glucose, insulin and leptin signaling pathways modulate nitric oxide (NO) synthesis in glucose-inhibited (GI) neurons in the ventromedial hypothalamus (VMH)
-
Canabal DD, Song Z, Potian JG, Beuve A, McArdle JJ, Routh VH. Glucose, insulin and leptin signaling pathways modulate nitric oxide (NO) synthesis in glucose-inhibited (GI) neurons in the ventromedial hypothalamus (VMH). Am J Physiol Regul Integr Comp Physiol 2008; 292: R1418-R1428.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.292
-
-
Canabal, D.D.1
Song, Z.2
Potian, J.G.3
Beuve, A.4
McArdle, J.J.5
Routh, V.H.6
-
73
-
-
34247578623
-
Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet
-
Tanaka T, Masuzaki H, Yasue S, Ebihara K, Shiuchi T, Ishii T, Arai N, Hirata M, Yamamoto H, Hayashi T, Hosoda K, Minokoshi Y, Nakao K. Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet. Cell Metab 2007; 5: 395-402.
-
(2007)
Cell Metab
, vol.5
, pp. 395-402
-
-
Tanaka, T.1
Masuzaki, H.2
Yasue, S.3
Ebihara, K.4
Shiuchi, T.5
Ishii, T.6
Arai, N.7
Hirata, M.8
Yamamoto, H.9
Hayashi, T.10
Hosoda, K.11
Minokoshi, Y.12
Nakao, K.13
-
74
-
-
33745834734
-
Ghrelin action in the brain controls adipocyte metabolism
-
Theander-Carrillo C, Wiedmer P, Cettour-Rose P, Nogueiras R, Perez-Tilve D, Pfluger P, Castaneda TR, Muzzin P, Schurmann A, Szanto I, Tschop MH, Rohner-Jeanrenaud F. Ghrelin action in the brain controls adipocyte metabolism. J Clin Invest 2006; 116: 1983-1993.
-
(2006)
J Clin Invest
, vol.116
, pp. 1983-1993
-
-
Theander-Carrillo, C.1
Wiedmer, P.2
Cettour-Rose, P.3
Nogueiras, R.4
Perez-Tilve, D.5
Pfluger, P.6
Castaneda, T.R.7
Muzzin, P.8
Schurmann, A.9
Szanto, I.10
Tschop, M.H.11
Rohner-Jeanrenaud, F.12
-
75
-
-
6344231416
-
Chronic central administration of ghrelin reverses the effects of leptin
-
Kim MS, Namkoong C, Kim HS, Jang PG, Kim Pak YM, Katakami H, Park JY, Lee KU. Chronic central administration of ghrelin reverses the effects of leptin. Int J Obes Relat Metab Disord 2004; 28: 1264-1271.
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 1264-1271
-
-
Kim, M.S.1
Namkoong, C.2
Kim, H.S.3
Jang, P.G.4
Kim Pak, Y.M.5
Katakami, H.6
Park, J.Y.7
Lee, K.U.8
-
76
-
-
4344710646
-
Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis
-
Perrin C, Knauf C, Burcelin R. Intracerebroventricular infusion of glucose, insulin, and the adenosine monophosphate-activated kinase activator, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, controls muscle glycogen synthesis. Endocrinology 2004; 145: 4025-4033.
-
(2004)
Endocrinology
, vol.145
, pp. 4025-4033
-
-
Perrin, C.1
Knauf, C.2
Burcelin, R.3
|