TBP recruitment to the U1 snRNA gene promoter is disrupted by substituting a U6 proximal sequence element A (PSEA) for the U1 PSEA

FEBS Letters

Volumn 582, Issue 16, 2008, Pages 2413-2416

  Barakat, Nermeen H ^a   Stumph, William E ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

Pre initiation complex assembly; RNA polymerase specificity; SNAPc; snRNA genes; TBP

Indexed keywords

DEOXYRIBONUCLEOPROTEIN; DNA DIRECTED RNA POLYMERASE III; RNA POLYMERASE II; SMALL NUCLEAR RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA; TATA BINDING PROTEIN;

ARTICLE; CELL LINE; CHROMOSOME SUBSTITUTION; DNA TRANSFECTION; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; GENE AMPLIFICATION; GENETIC TRANSCRIPTION; IMMUNOPRECIPITATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; TERMINAL OLIGOPYRIMIDINE TRACT;

ANIMALS; BINDING SITES; CHROMATIN IMMUNOPRECIPITATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; MUTATION; PROMOTER REGIONS (GENETICS); RNA POLYMERASE II; RNA, SMALL NUCLEAR; TATA-BOX BINDING PROTEIN; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 45549103582     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.06.003     Document Type: Article

References (21)

1. Dahlberg J.E., and Lund E. The genes and transcription of the major small nuclear RNAs. In: Birnstiel M.L. (Ed). Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles (1988), Springer Verlag KG, Heidelberg, Federal Republic of Germany 38-70
2. Parry H.D., Scherly D., and Mattaj I.W. Snurpogenesis: the transcription and assembly of U snRNP components. Trends Biochem. Sci. 14 (1989) 15-19
3. Lobo S.M., and Hernandez N.T. Transcription of snRNA genes by RNA polymerases II and III. In: Conaway R.C., and Conaway J.W. (Eds). Transcription: Mechanisms and Regulation (1994), Raven Press, New York, NY 127-159
4. Das G., Henning D., and Reddy R. Structure, organization, and transcription of Drosophila U6 small nuclear RNA genes. J. Biol. Chem. 262 (1987) 1187-1193
5. McNamara K.J., and Stumph W.E. Site-directed mutational analysis of a U4 small nuclear RNA gene proximal sequence element: localization and identification of functional nucleotides. J. Biol. Chem. 265 (1990) 9728-9731
6. Lobo S.M., Ifill S., and Hernandez N. cis-Acting elements required for RNA polymerase II and III transcription in the human U2 and U6 snRNA promoters. Nucleic Acids Res. 18 (1990) 2891-2899
7. Lescure A., Carbon P., and Krol A. The different positioning of the proximal sequence element in the Xenopus RNA polymerase II and III snRNA promoters is a key determinant which confers RNA polymerase III specificity. Nucleic Acids Res. 19 (1991) 435-441
8. Wendelburg B.J., and Marzluff W.F. Two promoter elements are necessary and sufficient for expression of the sea urchin U1 snRNA gene. Nucleic Acids Res. 20 (1992) 3743-3751
9. Zamrod Z., Tyree C.M., Song Y., and Stumph W.E. In vitro transcription of a Drosophila U1 small nuclear RNA gene requires TATA box-binding protein and two proximal cis-acting elements with stringent spacing requirements. Mol. Cell. Biol. 13 (1993) 5918-5927
10. Li J.M., Parsons R.A., and Marzluff W.F. Transcription of the sea urchin U6 gene in vitro requires a TATA-like box, a proximal sequence element, and sea urchin USF, which binds an essential E box. Mol. Cell. Biol. 14 (1994) 2191-2200
11. Hernandez G., Valafar F., and Stumph W.E. Insect small nuclear RNA gene promoters evolve rapidly yet retain conserved features involved in determining promoter activity and RNA polymerase specificity. Nucleic Acids Res. 35 (2007) 21-34
12. Sadowski C.L., Henry R.W., Lobo S.M., and Hernandez N. Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE. Genes Dev. 7 (1993) 1535-1548
13. Waldschmidt R., Wanandi I., and Seifart K.H. Identification of transcription factors required for the expression of mammalian U6 genes in vitro. EMBO J. 10 (1991) 2595-2603
14. Murphy S., Yoon J.B., Gerster T., and Roeder R.G. Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes. Mol. Cell. Biol. 12 (1992) 3247-3261
15. Das A., Zhang Q., Palenchar J.B., Chatterjee B., Cross G.A., and Bellofatto V. Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression. Mol. Cell. Biol. 25 (2005) 7314-7322
16. Schimanski B., Nguyen T.N., and Gunzl A. Characterization of a multisubunit transcription factor complex essential for spliced-leader RNA gene transcription in Trypanosoma brucei. Mol. Cell. Biol. 25 (2005) 7303-7313
17. Jensen R.C., Wang Y., Hardin S.B., and Stumph W.E. The proximal sequence element (PSE) plays a major role in establishing the RNA polymerase specificity of Drosophila U-snRNA genes. Nucleic Acids Res. 26 (1998) 616-622
18. McNamara-Schroeder K.J., Hennessey R.F., Harding G.A., Jensen R.C., and Stumph W.E. The Drosophila U1 and U6 gene proximal sequence elements act as important determinants of the RNA polymerase specificity of snRNA gene promoters in vitro and in vivo. J. Biol. Chem. 276 (2001) 31786-31792
19. Lai H.T., Chen H., Li C., McNamara-Schroeder K.J., and Stumph W.E. The PSEA promoter element of the Drosophila U1 snRNA gene is sufficient to bring DmSNAPc into contact with 20 base pairs of downstream DNA. Nucleic Acids Res. 33 (2005) 6579-6586
20. Wang Y., and Stumph W.E. Identification and topological arrangement of Drosophila proximal sequence element (PSE)-binding protein subunits that contact the PSEs of U1 and U6 snRNA genes. Mol. Cell. Biol. 18 (1998) 1570-1579
21. Li C., Harding G.A., Parise J., McNamara-Schroeder K.J., and Stumph W.E. Architectural arrangement of cloned proximal sequence element-binding protein subunits on Drosophila U1 and U6 snRNA gene promoters. Mol. Cell. Biol. 24 (2004) 1897-1906