The use of Minilabs® to improve the testing capacity of regulatory authorities in resource limited settings: Tanzanian experience

Health Policy

Volumn 87, Issue 2, 2008, Pages 217-222

  Risha, Peter Gasper ^a   Msuya, Zera ^b   Clark, Malcolm ^c   Johnson, Keith ^c   Ndomondo Sigonda, Margareth ^b   Layloff, Thomas ^c  

^a MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^b Tanzania Food and Drugs Authority   (Tanzania)

^c MANAGEMENT SCIENCES FOR HEALTH   (United States)

Author keywords

Minilab; Quality assurance; Substandard drugs; Testing capacity

Indexed keywords

AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; ANTIMALARIAL AGENT; ARTESUNATE; CIPROFLOXACIN; COTRIMOXAZOLE; DIDANOSINE; ERYTHROMYCIN; FANSIDAR; INDINAVIR; LAMIVUDINE; METRONIDAZOLE; NEVIRAPINE; QUININE DERIVATIVE; STAVUDINE; ZIDOVUDINE;

ARTICLE; AUTHORITY; DRUG QUALITY; DRUG SCREENING; GOLD STANDARD; GOOD LABORATORY PRACTICE; HEALTH CARE FACILITY; HIGH THROUGHPUT SCREENING; MARKET; POSTMARKETING SURVEILLANCE; RELIABILITY; TANZANIA; TECHNIQUE; THIN LAYER CHROMATOGRAPHY; TOTAL QUALITY MANAGEMENT; COMPUTER PROGRAM; DECISION TREE; DRUG CONTAMINATION; DRUG INDUSTRY; DRUG INSTILLATION; EVALUATION; GOVERNMENT REGULATION; HEALTH CARE PLANNING; HEALTH CARE QUALITY; HUMAN; INSTRUMENTATION; INTERNATIONAL COOPERATION; METHODOLOGY; PRESCRIPTION; PUBLIC HEALTH SERVICE; QUALITY CONTROL; STANDARD;

CHROMATOGRAPHY, THIN LAYER; DECISION TREES; DRUG CONTAMINATION; DRUG INDUSTRY; GOVERNMENT REGULATION; HEALTH RESOURCES; HUMANS; INSTILLATION, DRUG; INTERNATIONALITY; PRESCRIPTIONS, DRUG; PRODUCT SURVEILLANCE, POSTMARKETING; PROGRAM EVALUATION; PUBLIC HEALTH ADMINISTRATION; QUALITY CONTROL; SOFTWARE DESIGN; TANZANIA;

EID: 45549088759     PISSN: 01688510     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healthpol.2007.12.010     Document Type: Article

References (15)

1. World Health Organization. Unpublished paper of the WHO Division of Drug Management and Policies 1999: summary of WHO counterfeit drug database as of April 1999. Geneva; 1999.
2. Roy J. The menace of substandard drugs. World Health Forum 8 (1994) 202-206
3. Shakoor O., Taylor R.B., and Berhens R.H. Assessment of the incidence of substandard drugs in developing countries. Tropical Medicine International Health 2 (1997) 839-845
4. Taylor R.B., Shakoor O., Behrens R.H., Everard M., Low A.S., Wangboonskul J., et al. Pharmacopoeial quality of drugs supplied by Nigerian pharmacies. Lancet 357 (2001) 1933-1936
5. Newton P., Proux S., Green M., Smithuis F., Rozendaal J., Prakongpan S., et al. Fake artesunate in Southeast Asia. Lancet 357 (2001) 1948-1950
6. Kenyon A.S., Flinn P.E., and Layloff T.P. Rapid screening of pharmaceuticals by thin-layer chromatography: analysis of essential drugs by visual methods. Journal AOAC International 78 (1995) 41
7. Kenyon AS, Layloff TP. World Health Organization report PHARM/95.290: rapid screening of pharmaceuticals by thin-layer chromatography. Geneva; 1995.
8. Busch K.L. Cost analysis of determinations with planar chromatography and column chromatography. Journal of Planar Chromatography 7 (1994) 318
9. World Health Organization. Report of the assessment of the problem of counterfeit drugs in Myanmar and Vietnam: study carried out in cooperation with the Governments of Myanmar and Vietnam. WHO unpublished document, WHO/DAP/98.17. Geneva; 1998.
10. ®-Protection Against Counterfeited and Substandard Pharmaceuticals 2007. www.gphf.org/web/en/minilab/index.htm; 2007.
11. Centre for Pharmaceutical Management. Access to essential medicines: Tanzania 2001 (2003), Management Sciences for Health, Arlington, VA
12. Risha P., Msuya Z., Ndomondo-Sigonda M., and Layloff T. Proficiency testing as a tool to assess the performance of visual TLC quantitation estimates. Journal AOAC International 89 (2006) 1300-1304
13. Lon C.T., Tsuyuoka R., Phanouvong S., Nivanna N., Socheat D., Sokhan C., et al. Counterfeit and substandard antimalaria drugs in Cambodia. Transactions of the Royal Society of Tropical Medicine and Hygiene 100 (2006) 1019-1024
14. Risha P.G., Shewiyo D., Msami A., Masuki G., Vergote G., Vervaet C., et al. In vitro evaluation of the quality of essential drugs on the Tanzanian market. Tropical Medicine International Health 7 (2002) 701-707
15. Kayumba P.C., Risha P.G., Shewiyo D., Msami A., Masuki G., Ameye D., et al. The quality of essential antimicrobial and antimalarial drugs marketed in Rwanda and Tanzania: influence of tropical storage conditions on in vitro dissolution. Journal Clinical Pharmacy Therapeutics 29 (2004) 331-338