Carrier screening for β-thalassemia during pregnancy in India: A 7-year evaluation

Genetic Testing

Volumn 12, Issue 2, 2008, Pages 181-185

  Colah, Roshan ^a   Surve, Reema ^a   Wadia, Marukh ^a   Solanki, Prakash ^a   Mayekar, Pramod ^a   Thomas, Mariamma ^a   Gorakshakar, Ajit ^a   Dastur, Adi ^b   Mohanty, Dipika ^a  

^a KEM HOSPITAL   (India)

^b Hon Consultant Pediatrician   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BETA THALASSEMIA; FEMALE; FIRST TRIMESTER PREGNANCY; GENETIC COUNSELING; GENETIC SCREENING; HEMOGLOBINOPATHY; HETEROZYGOTE DETECTION; HIGH RISK PATIENT; HUMAN; INDIA; MAJOR CLINICAL STUDY; OSMOTIC FRAGILITY; PREGNANCY; PREGNANCY TERMINATION; PREGNANT WOMAN; PRENATAL DIAGNOSIS; SECOND TRIMESTER PREGNANCY; SPOUSE; THIRD TRIMESTER PREGNANCY;

ABORTION, EUGENIC; BETA-THALASSEMIA; CORDOCENTESIS; FEMALE; FETAL DISEASES; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HEMATOLOGIC TESTS; HETEROZYGOTE; HETEROZYGOTE DETECTION; HUMANS; INDIA; MALE; OSMOTIC FRAGILITY; PREGNANCY; PRENATAL CARE; PRENATAL DIAGNOSIS; PROGRAM EVALUATION;

EID: 45549083312     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/gte.2007.0066     Document Type: Article

References (21)

1. Angastiniotis MA, Hadjiminas MG (1981) Prevention of thalassemia in Cyprus. Lancet 8216:369-371.
2. Cao A (2002) Carrier screening and genetic counseling in bthalassemia. Int J Hematol 76:105-113.
3. Chow J, Phelan L, Bain BJ (2005) Evaluation of single tube osmotic fragility as a screening test for thalassemia. Am J Hematol 79:198-201.
4. Colah RB, Gorakshakar AC, Lu CY, Nadkarni AH, Desai SN, Pawar AR, Lulla CP, Krishnamoorthy R, Mohanty D (1997) Application of covalent reverse dot blot hybridization for rapid prenatal diagnosis of the common Indian thalassemia syndromes. Ind J Hematol Blood Transf 15:10-13.
5. Colah RB, Gorakshakar A, Surve R, Wadia M, Ghosh K, Mohanty D (2001) Feasibility of antenatal screening of β-thalassemia in Mumbai, India. Acta Haematol 105:252.
6. George E, Khoo SK, Mokhtar AB, Nor Aini U (2005) Screening for thalassemia in pregnant women: a laboratory perspective. Malaysian J Med Health Sci 1:111-117.
7. Giardano PC, Plancke A, van Meir CA, Janssen CA, Kok PJ, van Rooijen-Nijdam IH, Tanis BC, van Huisseling JC, Versteegh FG (2006) Carrier diagnostics and prevention of hemoglobin-opathies in early pregnancy in the Netherlands: a pilot study. Prenat Diagn 26:719-724.
8. Gorakshakar AC, Colah R, Nadkarni A, Desai S (1990) Evaluation of the single tube osmotic fragility test in the detection of β-thalassemia trait. Natl Med J India 3:171-173.
9. Greengross P, Hickman M, Gill M, Dugan B, Davies SC (1999) Outcomes of universal antenatal screening for hemoglobinopathies. J Med Screen 6:3-10.
10. Keskin A, Turk T, Polat A, Koyuncu H, Saracoglu B (2000) Premarital screening of b-thalassemia trait in the province of Denizli, Turkey. Acta Haematol 104:31-33.
11. Lee AC, Wong KW, So KT, Cheng MY (1998) Why are thalassemia patients born when prenatal screening is available? Hong Kong Med J 4:121-124.
12. Liao C, Mo QH, Li J, Li LY, Huang YN, Hua L, Li QM, Zhang JZ, Feng Q, Zeng R, Zhong HZ, Jia SQ, Cui YY, Xu XM (2005) Carrier screening for alpha and beta thalassemia in pregnancy: the results of an 11 year prospective programme in Guangzhou Maternal and Neonatal hospital. Prenat Diagn 25:163-171.
13. Rangan S (2003) The public-private mix in India's revised national tuberculosis control programme - an update. J Indian Med Assoc 101:161-163.
14. Samavat A, Modell B (2004) Iranian national thalassemia screening programme. Br Med J 329:1134-1137.
15. Sanchaisuriya K, Fucharoen S, Fucharoen G, Ratanasiri T, Sanchaisuriya P, Changtrakul Y, Ulkosanakarn U, Ussawaphark W, Schelp FP (2005) A reliable screening protocol for thalassemia and hemoglobinopathies in pregnancy: an alternative approach to electronic blood cell counting. Am J Clin Pathol 123:113-118.
16. Sood SK, Madan N, Colah R, Sharma S, Apte SV (eds) (1993) Collaborative Study on Thalassemia: Report of an ICMR Task Force Study. Indian Council of Medical Research, New Delhi.
17. Tarazi I, Al Najjar E, Lulu N, Sirdah M (2007) Obligatory premarital tests for b-thalassemia in the Gaza strip: evaluation and recommendations. Int J Lab Hematol 29:111-118.
18. Thomas P, Oni L, Alli M, St. Hilaire J, Smith A, Leavey C, Banarsee R (2005) Antenatal screening for hemoglobinopathies in primary care: a whole system participatory action research project. Br J Gen Pract 55:424-428.
19. Toteja GS, Singh P, Dhillon BS, Saxena BN, Ahmed FU, Singh RP, Prakash B, Vijayaraghavan K, Singh Y, Rauf A, Sarma UC, Gandhi S, Behl L, Mukherjee K, Swami SS, Meru V, Chandra P, Chandrawati, Mohan U (2006) Prevalence of anemia among pregnant women and adolescent girls in 16 districts of India. Food Nutr Bull 27:311-315.
20. Wadia MR, Phanasgoankar SP, Nadkarni AH, Surve RR, Gorakshakar AC, Colah RB, Mohanty D (2002) Usefulness of automated chromatography for rapid fetal blood analysis for second trimester prenatal diagnosis of b-thalassemia. Prenat Diagn 22:153-157.
21. Weatherall DJ, Clegg JB (2001) The Thalassemia Syndromes, 4th ed. Blackwell Science Ltd. Oxford, UK.