Effect of Nigella sativa l. Oil on roridin e toxin administration on liver of male mice

Journal of Applied Animal Research

Volumn 31, Issue 2, 2007, Pages 161-164

  Qusti, Safaa Y ^a   El Sawi Mahmoud, Nagwa M ^a  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Antioxidants; Liver; Mycotoxin; Nigella sativa L. oil; Roridin E; Serum; Trichothecene

Indexed keywords

MUS; NIGELLA SATIVA;

EID: 45449116198     PISSN: 09712119     EISSN: 09741844     Source Type: Journal    
DOI: 10.1080/09712119.2007.9706653     Document Type: Article

References (25)

1. Al-Ghamdi, M.S. 2001. The anti inflammatory, analgesic and antipyretic activity of Nigella sativa. J. Ethnopharmacol., 76: 45-48.
2. Beutler, E., Duron, O. and Kelly, B.M. 1963. Improved method for the determination of blood glutathione. J. Lab. Clin. Med., 61: 882-888.
3. Boulos, L. 1983. Medicinal plants of North Africa reference publications. Algonac, M.I., pp., 108.
4. Bowers, G.N. Jr. and McComb, R.B. 1966. Continuous spectrophotometric method for measuring activity of serum alkaline phosphatase. Clin. Chem., 12: 70-89.
5. Dornand, J., Bonnfous, J.C., Favero, J. and Mani, J.C. 1982. Ecto 5-nucleotidase and adenosine deaminase activities of lymphoid cells. Bochem. Med., 28: 144-156.
6. El-Aaser, A.A. and El Merzabani, M.M. 1975. Simultaneous determinations of 5-nucleotidase and alkaline phosphate activity in serum. Z. Klin. Chem. Klin. Biochem., 1379: 563.
7. Habermehl, G.G., Busam, L., Heydel, P., Mebs, D., Tokania, C.H., Dobereiner, J. and Spraul, M.M. 1985. Macrocyclic trichotheeenes: cause of livestock poisoning by the barailian plant Baccharis coridifolia Toxicon, 23: 731-733.
8. Hag, A., Lobo, P.I., Al Tufail, A., Rama, N.R. and Al Sedairy, S.T. 1999. Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography. Int. J. Immunopharmacol., 21: 283-285.
9. Hossam, EL.M.O., Nagwa, M.E.S. and Abdel-Raheem, M.A.M.1997. Acute toxicity of the mycotoxin roridin E on liver and kidney of rats. J. Appl. Anim. Res., 12: 145-152.
10. Kinght, J.A., Anderson, S. and James, N. 1972. Chemical basis of sulfophovanilin reaction for estimating total lipids. J. Clin. Chem. 18: 199.
11. Lowry, O.H., Rosenbrough, N.J., Farr, A.L. and Randall, R.J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193: 265-275.
12. Meral, I., Yener, Z., Kahraman, T. and Mert, N. 2001. Effect of Nigella sativa on glucose concentration, lipid peroxidation, antioxidant defense system and liver damage in experimentally-induced diabetic rabbits. J. Vet. Med. A. Physiol Pathol. Clin. Med., 48: 593-599.
13. Mistra, M.L. and Fridoviech, I.1992. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem., 247: 3170-3175.
14. Morsi, N.M. 2000. Antimicrobial effect of crude extracts of Nigella Sativa on multiple antibiotic resistant bacteria. Act. Microbial Pol., 49: 63-74.
15. Nagi, M.N., Alam, K, Badary, O.A., Al-shabanah, O.A., Alsawaf, H.A. and Al-Bekairi, A.M. 1999. Thymoquinone protects against carbon tetra chloride hepatotoxicity in mice via an antioxidant mechanism. Biochem. Mol. Biol. Int., 47: 153-159.
16. Nagwa, El. S., Mahmoud, Mohamed, M. El-messemy and Osama, A.Y. 2000. Biochemical studies of verrucarin J. in male mice lever. J. Toxicol. Toxin Review, 19: 265-273.
17. Nagwa, M.E.S., Mohamed, T.E.W. and Osama, A.Y. 2001. Effect of verrucarin J. toxin on liver and kidney tissue of male mice. Texas. J. Sci., 53: 375-384.
18. Salem, M.L. and Hossain, M.S. 2000. Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus. Anti Immunopharmacol., 22: 729-740.
19. Slater, T.F. and Sawyer, B.C. 1971. The stimulatory effect of carbon tetrachloride and other halogenoalkalines on peroxidative reactions in rat liver fractions in vitro. Biochem., 123: 805-814.
20. Swamy, S.M. and Tan, B.K. 2000. Cytotoxic and immuno- potentiating effect of ethanolic extract of Nigella sativa L seeds. J. Ethno-Pharmacol, 70: 1-7.
21. Szasz, G. 1969. Akinetic photometric method for serum y-glutamyl transpeptidase. Clin. Chem., 15: 124.
22. Tito, N.H., Ngwa, M.EL.S. and Zakaria, M. 2002. Antitumor activity of the Egyption Nigella sativa L-oil induced by microcyctin-LR in male mice. J. Union Arab Biol., 17 (A): 541-556. (9th international conference) Syria.
23. Ueno, Y. 1976. Trichotheeenes: overview address. In: Rodricks, J.V., Hesseltine, C.W. and Mehlman, M.A. eds., Mycotoxins: Pathotox Publishers Inc., 189-207 pp.
24. Ueno, Y. 1983. Trichothecenes: Chemical, Biological and Toxicological Aspects. Develop. Food Sci., Vol. 4. Elsevier, New York.
25. Ueno, Y., Nakajima, M., Sakai, K., Inshii, K., Sato, N. and Shimada, N. 1973. Comparative toxicology of trichothecene mycotoxins: inhibition of protein synthesis in animal cells. J. Biochem., 74: 283-296.