Convenient synthesis of (2S,3R,4R,5S,6R)-2-(3-(4-ethylbenzyl)-4-chlorophenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol

Chinese Chemical Letters

Volumn 19, Issue 7, 2008, Pages 814-816

  Liu, Yong Hai ^a   Li, Da Li ^a   De Lu, Lu ^a   Miao, Zhen Yuan ^b  

^a NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Inhibitor; Preparation; Sodium glucose co transporter 2; Type 2 diabetes

Indexed keywords

EID: 45449115151     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2008.05.009     Document Type: Article

References (9)

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5. W. Washburn, W. Meng, US Patent 20060063722 (2006).
6. M. Eckhardt, F. Himmelsbach, P. Eickelmann, US Patent 20060074031 (2006).
7. Chang C.P., Huang Y.L., and Hong F.E. Tetrahedron 61 (2005) 3835
8. 2 was added for 12 h at 25 °C. The solvent was filtrated, filter cake was washed by EA, the filtrate was concentrated in vacuo to give oil. The oil was purified with silicon column to get a glassy off white solid.
9. 5: C 64.20, H 6.41; Found C 64.11, H 6.43.