Concept of combinatorial de novo design of drug-like molecules by particle swarm optimization

Chemical Biology and Drug Design

Volumn 72, Issue 1, 2008, Pages 16-26

  Hartenfeller, Markus ^a   Proschak, Ewgenij ^a   Schüller, Andreas ^a   Schneider, Gisbert ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Bioinformatics; Cheminformatics; Drug design; Evolutionary algorithm; Library design; PPAR

Indexed keywords

FARGLITAZAR; GW 590735; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; ROSIGLITAZONE;

ALGORITHM; ARTICLE; CHEMICAL REACTION; COMBINATORIAL LIBRARY; DRUG DESIGN; DRUG STRUCTURE; PHARMACOPHORE; PRIORITY JOURNAL;

ALGORITHMS; COMBINATORIAL CHEMISTRY TECHNIQUES; CROSS-LINKING REAGENTS; DRUG DESIGN; LIGANDS; MODELS, MOLECULAR; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS;

EID: 45449111186     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2008.00672.x     Document Type: Article

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