Somatic nerve stimulation evokes qualitatively different somatosympathetic responses in the cervical and splanchnic sympathetic nerves in the rat

Brain Research

Volumn 1217, Issue , 2008, Pages 139-147

  McMullan, Simon ^a   Pathmanandavel, Karrnan ^b   Pilowsky, Paul M ^a   Goodchild, Ann K ^a  

^a MACQUARIE UNIVERSITY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Baroreflex; Differential control; Electrophysiology; Nociception; RVLM; Vasomotor

Indexed keywords

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANTERIOR HYPOTHALAMUS; ARTICLE; ELECTROSTIMULATION; EVOKED SOMATOSENSORY RESPONSE; FREQUENCY MODULATION; NERVE STIMULATION; NOCICEPTIVE RECEPTOR; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPLANCHNIC NERVE; STATISTICAL SIGNIFICANCE; SYMPATHETIC INNERVATION; SYMPATHETIC NERVE; SYMPATHETIC TONE;

AFFERENT PATHWAYS; ANIMALS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; MALE; MEDULLA OBLONGATA; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SPLANCHNIC NERVES; SYMPATHETIC NERVOUS SYSTEM;

RATTUS;

EID: 45449106976     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.04.034     Document Type: Article

References (54)

1. Abram S.E., Kostreva D.R., Hopp F.A., and Kampine J.P. Cardiovascular responses to noxious radiant heat in anesthetized cats. Am. J. Physiol. 245 (1983) R576-R580
2. Adachi T., Sato A., Sato Y., and Schmidt R.F. Depending on the mode of application morphine enhances or depresses somatocardiac sympathetic A- and C-reflexes in anesthetized rats. Neurosci. Res. 15 (1992) 281-288
3. Beacham W.S., and Perl E.R. Background and reflex discharge of sympathetic preganglionic neurones in the spinal cat. J. Physiol. 172 (1964) 400-416
4. Behbehani M.M. Functional characteristics of the midbrain periaqueductal gray. Prog. Neurobiol. 46 (1995) 575-605
5. Carrive P., Dampney R.A., and Bandler R. Excitation of neurones in a restricted portion of the midbrain periaqueductal grey elicits both behavioural and cardiovascular components of the defence reaction in the unanaesthetised decerebrate cat. Neurosci. Lett. 81 (1987) 273-278
6. Coote J.H., and Perez-Gonzalez J.F. The response of some sympathetic neurones to volleys in various afferent nerves. J. Physiol. 208 (1970) 261-278
7. Coote J.H. Landmarks in understanding the central nervous control of the cardiovascular system. Exp Physiol. 92 (2007) 3-18
8. Craig A.D. Interoception: the sense of the physiological condition of the body. Curr. Opin. Neurobiol. 13 (2003) 500-505
9. Dembowsky K., Lackner K., Czachurski J., and Seller H. Tonic catecholaminergic inhibition of the spinal somato-sympathetic reflexes originating in the ventrolateral medulla oblongata. J. Auton. Nerv. Syst. 3 (1981) 277-290
10. Djouhri L., and Lawson S.N. Increased conduction velocity of nociceptive primary afferent neurons during unilateral hindlimb inflammation in the anaesthetised guinea-pig. Neuroscience 102 (2001) 669
11. Djouhri L., Koutsikou S., Fang X., McMullan S., and Lawson S.N. Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors. J. Neurosci. 26 (2006) 1281-1292
12. Ermirio R., Ruggeri P., Molinari C., and Weaver L.C. Somatic and visceral inputs to neurons of the rostral ventrolateral medulla. Am. J. Physiol. 265 (1993) R35-R40
13. Fang X., McMullan S., Lawson S.N., and Djouhri L. Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivo. J. Physiol. 565 (2005) 927-943
14. Huangfu D., Hwang L.J., Riley T.A., and Guyenet P.G. Role of serotonin and catecholamines in sympathetic responses evoked by stimulation of rostral medulla. Am. J. Physiol. 266 (1994) R338-R352
15. Janig W., Sato A., and Schmidt R.F. Reflexes in postganglionic cutaneous fibres by stimulation of group I to group IV somatic afferents. Pflugers Arch. 331 (1972) 244-256
16. Janig W. Vasoconstrictor systems supplying skeletal muscle, skin, and viscera. Clin. Exp. Hypertens. A. 6 (1984) 329-346
17. Kerman I.A., and Yates B.J. Patterning of somatosympathetic reflexes. Am. J. Physiol.,-Regul. Integr. Comp. Physiol. 277 (1999) R716-R724
18. Kiely J.M., and Gordon F.J. Role of rostral ventrolateral medulla in centrally mediated pressor responses. Am. J. Physiol. 267 (1994) H1549-H1556
19. Kimura A., Ohsawa H., Sato A., and Sato Y. Somatocardiovascular reflexes in anesthetized rats with the central nervous system intact or acutely spinalized at the cervical level. Neurosci. Res. 22 (1995) 297-305
20. Kimura A., Sato A., Sato Y., and Suzuki H. A- and C-reflexes elicited in cardiac sympathetic nerves by single shock to a somatic afferent nerve include spinal and supraspinal components in anesthetized rats. Neurosci. Res. 25 (1996) 91-96
21. Lawson S.N. Phenotype and function of somatic primary afferent nociceptive neurones with C-, Adelta- or Aalpha/beta-fibres. Exp. Physiol. 87 (2002) 239-244
22. Le Bars D., Guilbaud G., Jurna I., and Besson J.M. Differential effects of morphine on responses of dorsal horn lamina V type cells elicited by A and C fibre stimulation in the spinal cat. Brain Res. 115 (1976) 518
23. Li P., and Lovick T.A. Excitatory projections from hypothalamic and midbrain defense regions to nucleus paragigantocellularis lateralis in the rat. Exp. Neurol. 89 (1985) 543-553
24. Li W.M., Liu X., Kumada M., and Sato A. Excitation of baroreceptors depresses A- and C-components of the somato-cardiac sympathetic reflex in anesthetized rats. Jpn. J. Physiol. 48 (1998) 261-266
25. Lidierth M. Pulser: user-friendly, graphical user-interface based software for controlling stimuli during data acquisition with Spike2 for Windows. J. Neurosci. Methods 141 (2005) 243-250
26. Lovick T.A. Midbrain influences on ventrolateral medullo-spinal neurones in the rat. Exp. Brain Res. 90 (1992) 147-152
27. Lovick T.A. The periaqueductal gray-rostral medulla connection in the defence reaction: efferent pathways and descending control mechanisms. Behav. Brain Res. 58 (1993) 19-25
28. Lumb B.M. Inescapable and escapable pain is represented in distinct hypothalamic-midbrain circuits: specific roles for Adelta- and C-nociceptors. Exp. Physiol. 87 (2002) 281-286
29. Lumb B.M., Parry D.M., Semenenko F.M., McMullan S., and Simpson D.A. C-nociceptor activation of hypothalamic neurones and the columnar organisation of their projections to the periaqueductal grey in the rat. Exp. Physiol. 87 (2002) 123-128
30. Makeham J.M., Goodchild A.K., Costin N.S., and Pilowsky P.M. Hypercapnia selectively attenuates the somato-sympathetic reflex. Respir. Physiol. Neurobiol. 140 (2004) 133-143
31. Makeham J.M., Goodchild A.K., and Pilowsky P.M. NK1 receptor activation in rat rostral ventrolateral medulla selectively attenuates somato-sympathetic reflex while antagonism attenuates sympathetic chemoreflex. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 (2005) R1707-R1715
32. McCall R.B., and Harris L.T. Sympathetic alterations after midline medullary raphe lesions. Am. J. Physiol. 253 (1987) R91-R100
33. McMullan S., and Lumb B.M. Spinal dorsal horn neuronal responses to myelinated versus unmyelinated heat nociceptors and their modulation by activation of the periaqueductal grey in the rat. J. Physiol. 576 (2006) 547-556
34. Miyawaki T., Pilowsky P., Sun Q.J., Minson J., Suzuki S., Arnolda L., Llewellyn-Smith I., and Chalmers J. Central inspiration increases barosensitivity of neurons in rat rostral ventrolateral medulla. Am. J.Physiol. 268 (1995) R909-R918
35. Miyawaki T., Goodchild A.K., and Pilowsky P.M. Rostral ventral medulla 5-HT1A receptors selectively inhibit the somatosympathetic reflex. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280 (2001) R1261-R1268
36. Miyawaki T., Goodchild A.K., and Pilowsky P.M. Activation of mu-opioid receptors in rat ventrolateral medulla selectively blocks baroreceptor reflexes while activation of delta opioid receptors blocks somato-sympathetic reflexes. Neuroscience 109 (2002) 133-144
37. Morrison S.F., Milner T.A., and Reis D.J. Reticulospinal vasomotor neurons of the rat rostral ventrolateral medulla: relationship to sympathetic nerve activity and the C1 adrenergic cell group. J. Neurosci. 8 (1988) 1286-1301
38. Morrison S.F. Differential control of sympathetic outflow. Am. J. Physiol., Regul. Integr. Comp. Physiol. 281 (2001) R683-R698
39. Morrison S.F., and Reis D.J. Reticulospinal vasomotor neurons in the RVL mediate the somatosympathetic reflex. Am. J. Physiol. 256 (1989) R1084-R1097
40. Morrison S.F., and Reis D.J. Responses of sympathetic preganglionic neurons to rostral ventrolateral medullary stimulation. Am. J. Physiol. 261 (1991) R1247-R1256
41. Nagata O., Li W.M., and Sato A. Glutamate N-methyl-d-aspartate (NMDA) and non-NMDA receptor antagonists administered into the brain stem depress the renal sympathetic reflex discharges evoked by single shock of somatic afferents in anesthetized rats. Neurosci Lett. 201 (1995) 111-114
42. Pilowsky P.M., Miyawaki T., Minson J.B., Sun Q.J., Arnolda L.F., Llewellyn-Smith I.J., and Chalmers J.P. Bulbospinal sympatho-excitatory neurons in the rat caudal raphe. J. Hypertens 13 (1995) 1618-1623
43. Sato A., and Schmidt R.F. Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics. Physiol. Rev. 53 (1973) 916-947
44. Sato A., Sato Y., and Schmidt R.F. Modulation of somatocardiac sympathetic reflexes mediated by opioid receptors at the spinal and brainstem level. Exp. Brain Res. 105 (1995) 1-6
45. Schreihofer A.M., and Guyenet P.G. Identification of C1 presympathetic neurons in rat rostral ventrolateral medulla by juxtacellular labeling in vivo. J. Comp. Neurol. 387 (1997) 524-536
46. Stornetta R.L., Morrison S.F., Ruggiero D.A., and Reis D.J. Neurons of rostral ventrolateral medulla mediate somatic pressor reflex. Am. J. Physiol. 256 (1989) R448-R462
47. Sun M.K., and Spyer K.M. Nociceptive inputs into rostral ventrolateral medulla-spinal vasomotor neurones in rats. J. Physiol. 436 (1991) 685-700
48. Torebjork H.E., and Ochoa J.L. Specific sensations evoked by activity in single identified sensory units in man. Acta Physiol. Scand. 110 (1980) 445
49. van der Plas J., Maes F.W., and Bohus B. Electrophysiological analysis of midbrain periaqueductal gray influence on cardiovascular neurons in the ventrolateral medulla oblongata. Brain Res. Bull. 38 (1995) 447-456
50. Verberne A.J., and Guyenet P.G. Midbrain central gray: influence on medullary sympathoexcitatory neurons and the baroreflex in rats. Am. J. Physiol. 263 (1992) R24-R33
51. Verberne A.J., Stornetta R.L., and Guyenet P.G. Properties of C1 and other ventrolateral medullary neurones with hypothalamic projections in the rat. J. Physiol. 517 Pt 2 (1999) 477-494
52. Wyszogrodski I., and Polosa C. The inhibition of sympathetic preganglionic neurons by somatic afferents. Can. J. Physiol. Pharmacol. 51 (1973) 29-38
53. Yeomans D.C., Pirec V., and Proudfit H.K. Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: behavioural evidence. Pain 68 (1996) 133
54. Zanzinger J., Czachurski J., Offner B., and Seller H. Somato-sympathetic reflex transmission in the ventrolateral medulla oblongata: spatial organization and receptor types. Brain Res. 656 (1994) 353-358