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pKa values for amines examined in this study (values in parentheses were the means of measurements duplicated, 3-amino-5- methylpyrazole (3A5MPyzol, 4.7 (4.70, 3-aminopyridine (3APy, 6.0 (6.03, bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane (Bis-Tris, 6.5 (6.47, 2-aminopyridine (2APy, 6.7 (6.70, N-(3-morpholino)-1,2-propanediol (3MO1, 2Pdiol, 6.8 (6.76, 4-(2-hydroxyethyl)morpholine (HEMO, 6.9 (6.93, imidazole (Im, 7.0 (6.99, 1-methylimidazole (IMeIm, 7.0 (7.03, 4-methylimidazole (4MeIm, 7.5 (7.54, 4-ethylmorpholine (EMO, 7.7 (7.71, triethanolamine (TEA, 7.7 (7.72, triisopropanolamine (TIPA, 7.8 (7.82, 2-methylimidazole (2MeIm, 7.9 (7.87, N-methyldiethanolamine (MDEA, 8.5 (8.51, N-n-butyldiethanolamine (nBDEA, 8.8 (8.77, 1-(2-hydroxyethyl)-4-(3-hydroxypropyl)piperidine (1HE4HPPD, 9.4 (9.37, and 1-(2-hydroxyethyl)piperidine (HEPD, 9.5 9.49
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a values for amines examined in this study (values in parentheses were the means of measurements duplicated): 3-amino-5- methylpyrazole (3A5MPyzol): 4.7 (4.70); 3-aminopyridine (3APy): 6.0 (6.03); bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane (Bis-Tris): 6.5 (6.47); 2-aminopyridine (2APy): 6.7 (6.70); N-(3-morpholino)-1,2-propanediol (3MO1, 2Pdiol): 6.8 (6.76); 4-(2-hydroxyethyl)morpholine (HEMO): 6.9 (6.93); imidazole (Im): 7.0 (6.99); 1-methylimidazole (IMeIm): 7.0 (7.03); 4-methylimidazole (4MeIm): 7.5 (7.54); 4-ethylmorpholine (EMO): 7.7 (7.71); triethanolamine (TEA): 7.7 (7.72); triisopropanolamine (TIPA): 7.8 (7.82); 2-methylimidazole (2MeIm): 7.9 (7.87); N-methyldiethanolamine (MDEA): 8.5 (8.51); N-n-butyldiethanolamine (nBDEA): 8.8 (8.77); 1-(2-hydroxyethyl)-4-(3-hydroxypropyl)piperidine (1HE4HPPD): 9.4 (9.37); and 1-(2-hydroxyethyl)piperidine (HEPD): 9.5 (9.49).
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Supporting Information is available electronically on the CSJ-Journal Web site, http://www.csj.jp/journals/chem-lett/ index.html.
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Supporting Information is available electronically on the CSJ-Journal Web site, http://www.csj.jp/journals/chem-lett/ index.html.
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In The Structure and Reactions of Heterocyclic Compounds, ed. by M. H. Palmer, Edward Arnold Publisher Ltd, London, 1967, pp. 105-144
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In The Structure and Reactions of Heterocyclic Compounds, ed. by M. H. Palmer, Edward Arnold Publisher Ltd., London, 1967, pp. 105-144.
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