The influence of lipoprotein lipase gene variation on postprandial lipoprotein metabolism

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 9, 2004, Pages 4721-4728

  López Miranda, José ^a   Cruz, Gracia ^a   Gómez, Purificación ^a   Marín, Carmen ^a   Paz, Elier ^a   Pérez Martínez, Pablo ^a   Fuentes, Francisco J ^a   Ordovas, José M ^b   Pérez Jiménez, Francisco ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPROTEIN LIPASE; RETINOL; RETINOL PALMITATE; TRIACYLGLYCEROL;

ADULT; ALLELE; ARTICLE; BODY FAT; BODY WEIGHT; CARDIOVASCULAR RISK; CONTROLLED STUDY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; HYPERLIPIDEMIA; LIPOPROTEIN METABOLISM; MALE; NORMAL HUMAN; POSTPRANDIAL STATE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ADOLESCENT; ADULT; GENOTYPE; HUMANS; LIPOPROTEIN LIPASE; LIPOPROTEINS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POSTPRANDIAL PERIOD; REGRESSION ANALYSIS; TRIGLYCERIDES;

EID: 4544386082     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031642     Document Type: Article

References (46)

1. Goldberg I 1996 Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J Lipid Res 37:693-707
2. Olivecrona T, Bengtsson-Olivecrona G 1993 Lipoprotein lipase and hepatic lipase. Curr Opin Lipidol 4:187-196
3. Beisiegel U, Weber W, Bengtsson-Olivecrona G 1991 Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein. Proc Natl Acad Sci USA 88:8342-8346
4. Saxena U, Klein MG, Vanni TM, Goldberg IJ 1992 Lipoprotein lipase increases low density lipoprotein retention by subendothelial cell matrix. J Clin Invest 89:373-380
5. Eisenberg S, Sehayek E, Olivecrona T, Vlodavsky I 1992 Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix. J Clin Invest 90:2013-2021
6. Rumsey SC, Obunike JC, Arad Y, Deckelbaum RJ, Golberg IJ 1992 Lipoprotein lipase-mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages. J Clin Invest 90:1504-1512
7. Gotoda T, Yamada N, Kawamura M, Kozaki K, Mori N, Ishibashi S, Shimano H, Takaku F, Yazakl Y, Furuichi Y 1991 Heterogenous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency. J Clin Invest 88:1856-1864
8. Benlian P, De Gennes JL, Foubert L, Zhang H, Gagné SE, Hayden M 1996 Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene. N Engl J Med 335:848-854
9. 291Ser) is associated with reduced HDL cholesterol levels in premature atherosclerosis. Nat Genet 10:28-34
10. Mailly F, Tugrul Y, Reymer PW, Bruin T, Seed M, Groenemeyer BF, Asplund-Carlson A, Vallance D, Winder AF, Miler GJ 1995 A common variant in the gene for lipoprotein lipase (Asn9-Asp). Functional implications and prevalence in normal and hyperlipidemic subjects. Arterioscler Thromb Vasc Biol 15:468-478
11. Gotoda T, Yamada N, Murase T, Shimano H, Shimada M, Harada K, Kawamura M, Kozaki K, Yazaki Y 1992 Detection of three separate DNA polymorphisms in the human lipoprotein lipase gene by gene amplification and restriction endonuclease digestion. J Lipid Res 33:1067-1072
12. Mattu RK, Needham EW, Morgan R, Rees A, Hackshaw AK, Stocks J, Elwood PC, Galton DJ 1994 DNA variants at the LPL gene locus associated with angiographically defined severity of atherosclerosis and serum lipoprotein levels in a Welsh population. Arterioscler Thromb 14:1090-1097
13. Vohl MC, Lamarche B, Moorjani S, Prud'homme D, Nadeau A, Bouchard C, Lupien PJ, Despres JP 1995 The lipoprotein lipase HindIII polymorphism modulates plasma triglyceride levels in visceral obesity. Arterioscler Thromb Vasc Biol 15:714-720
14. Heizmann C, Kirchgessner T, Kwiterovich PO, Ladias LA, Derby C, Antonarakis SE, Lusis AJ 1991 DNA polymorphism genotypes of the human lipoprotein lipase gene: possible association with high density lipoprotein levels. Hum Genet 86:578-584
15. Chamberlain JC, Thorn JA, Oka K, Galton DJ, Stocks J 1989 DNA Polymorphisms at the lipoprotein lipase gene: associations in normal and hypertriglyceridaemic subjects. Atherosclerosis 79:85-91
16. Thorn JA, Chamberlain JC, Alcolado JC, Oka K, Chan L, Stocks J, Galton DJ 1990 Lipoprotein lipase and hepatic lipase gene variants in coronary atherosclerosis. Atherosclerosis 85:55-60
17. Kobayashi J, Nishida T, Ameis D, Stahnke G, Scholz MC, Hashimoto H, Fukamachi I, Shirai K, Saito Y, Yoshida S 1992 A heterozygous mutation (the codon for Ser447-a stop codon) in lipoprotein lipase contributes to a defect in lipid interface recognition in a case with type I hyperlipidemia. Biochem Biophys Res Commun 182:70-77
18. Zhang H, Henderson H, Gagne SE, Clee SM, Miao L, Liu G, Hayden MR 1996 Common sequence variants of lipoprotein lipase: standardized studies of in vitro expression and catalytic function. Biochim Biophys Acta 1302:159-166
19. Stocks J, Thorn JA, Galton DJ 1992 Lipoprotein lipase genotypes for a common premature termination codon mutation detected by PCR-mediated site-directed mutagenesis and restriction digestion. J Lipid Res 33:853-857
20. Funke H, Assmann G 1995 The lowdown on lipoprotein lipase. Nat Genet 10:6-7
21. Groenemeijer BE, Hallman MD, Reymer PW, Gagne E, Kuivenhoven JA, Bruin T, Jansen H, Lie KI, Bruschke E, Hayden MR, Kastelein JJ 1997 Genetic variant showing a positive interaction with β-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group. Circulation 95:2628-2635
22. Kuivenhoven JA, Groenemeyer BE, Boer JM, Reymer PW, Berghuis R, Bruin T, Jansen H, Seidell JC, Kastelein JJ 1997 Ser447Stop mutation in lipoprotein lipase is associated with elevated HDL cholesterol levels in normolipidemic males. Arterioscler Thromb Vasc Biol 17:595-599
23. Humphries SE, Nicaud V, Margalef J, Tiret L, Talmud PJ 1998 Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: the European Atherosclerosis Research Study (EARS). Arterioscler Thromb Vasc Biol 18:526-534
24. Zilversmit DB 1979 Atherogenesis: a postprandial phenomenon. Circulation 60:473-485
25. Ginsberg HN, Jones J, Blaner WS, Thomas A, Karmally W, Fields L, Blood D, Begg MD 1995 Association of postprandial triglyceride and retinyl palmitate responses with newly diagnosed exercise-induced myocardial ischemia in middle-aged men and women. Arterioscler Thromb Vasc Biol 15:1829-1838
26. Patsch JR, Miesenbock G, Hopferwieser T, Muhlberger V, Knapp E, Dunn JK, Gotto Jr AM, Patsh W 1992 Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Arterioscler Thromb 12:1336-1345
27. Groot PH, van Stiphout WA, Krauss XH, Jansen H, van Tol A, van Ramshorst E, Chin-On S, Hofman A, Cresswell SR, Havekes L 1991 Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease. Arterioscler Thromb 11:653-662
28. Kugiyama K, Doi H, Takazoe K, Kawano H, Soejima H, Mizuno Y, Tsunoda R, Sakamoto T, Nakano T, Nakajima K, Ogawa H, Sugiyama S, Yoshimura M, Yasue H 1999 Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease. Circulation 99:2858-2860
29. Boerwinkle E, Brown S, Sharrett AR, Heiss G, Patsch W 1994 Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations. Am J Hum Genet 54:341-360
30. Bucolo G, David H 1973 Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 19:476-482
31. Allain CC, Poon LS, Chang CS, Richmond W, Fu PC 1974 Enzymatic determination of total serum cholesterol. Clin Chem 20:470-475
32. Riepponen P, Mamiemi J, Rautaoja T 1987 Immunoturbidimetric determination of apolipoproteins A-I and B in serum. Scand J Clin Lab Invest 47: 739-744
33. 2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem 28:1379-1388
34. Ruotolo G, Zhang H, Bentsianov V, Le NA 1992 Protocol for the study of the metabolism of retinyl esters in plasma lipoproteins during postprandial lipemia. J Lipid Res 33:1541-1549
35. De Ruyter MG, De Leenheer AP 1978 Simultaneous determination of retinol and retinyl esters in serum or plasma by reversed-phase high performance liquid chromatography. Clin Chem 24:1920-1923
36. Karpe F, Hamsten A 1994 Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE. J Lipid Res 35:1311-1317
37. Thorn JA, Needham EW, Mattu RK, Stocks J, Galton DJ 1998 The Ser447-Ter mutation of the lipoprotein lipase gene relates to variability of serum lipid and lipoprotein levels in monozygotic twins. J Lipid Res 39:437-441
38. Wilson DE, Emi M, Iverius PH, Hata A, Wu LL, Hillas E, Williams RR, Lalouel JM 1990 Phenotypic expression of heterozygous lipoprotein lipase deficiency in the extended pedigree of a proband homozygous for a missense mutation. J Clin Invest 86:735-750
39. 291Ser) results in altered postprandial chylomicron triglyceride and retinyl palmitate response in normolipidemic carriers. J Lipid Res 37:1675-1684
40. López Miranda J, Ordovás JM, Ostos MA, Marin C, Jansen S, Salas J, Blanco-Molina A, Jimenez-Pereperez JA, Lopez-Segura F, Perez-Jimenez F 1997 Dietary fat clearance in normal subjects is modulated by genetic variation at the apolipoprotein B gene locus. Arterioscler Thromb Vasc Biol 17:1532-1538
41. Ostos MA, López-Miranda J, Ordovas JM, Marin C, Blanco A, Castro P, Lopez-Segura F, Jimenez-Pereperez J, Perez-Jimenez F 1998 Dietary fat clearance is modulated by genetic variation in apolipoprotein A-IV gene locus. J Lipid Res 39:2493-2500
42. 291Ser gene variant. J Lipid Res 40: 1663-1670
43. Dichek HL, Parrott C, Ronan R, Brunzell JD, Brewer Jr HB, Santamarina-Fojo S 1993 Functional characterization of a chimeric protein genetically engineered from human lipoprotein lipase and human hepatic lipase. J Lipid Res 34:1393-1400
44. Davis RC, Wong H, Nikazy J, Wang K, Han Q, Schotz MC 1992 Chimeras of hepatic lipase and lipoprotein lipase. Domain localization of enzyme-specific properties. J Biol Chem 267:21499-21504
45. Jemaa R, Fumeron F, Poirier O, Lecerf L, Evans A, Arveiler D, Luc G, Cambou JP, Bard JM, Fruchart JC 1995 Lipoprotein lipase gene polymorphism: associations with myocardial infarction and lipoprotein levels, the ECTIM study. Etude Cas temoin Sur l'infarrus du Myicarde. J Lipid Res 36:2141-2146
46. Semenkovich CF, Wins M, Noe L, Etienne J, Chan L 1989 Insulin regulation of lipoprotein lipase activity in 3T3-L1 adipocytes is mediated at posttranscriptional and posttranslational levels. J Biol Chem 264:9030-9038