Current treatment practices in the management of cutaneous haemangioma

Expert Opinion on Pharmacotherapy

Volumn 5, Issue 9, 2004, Pages 1937-1942

  Chan, Yuin Chew ^a  

^a NATIONAL SKIN CENTRE   (Singapore)

Author keywords

Corticosteroid; Cyclophosphamide; Haemangioma; IFN ; Laser; Periorbital; Vincristine

Indexed keywords

ALPHA INTERFERON; AMINOTRANSFERASE; CEFALEXIN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; EMLA; ERYTHROMYCIN; HISTAMINE H2 RECEPTOR ANTAGONIST; LIDOCAINE; LIVE VACCINE; LIVER ENZYME; PARACETAMOL; PREDNISOLONE; RANITIDINE; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT ALPHA2B INTERFERON; TRIAMCINOLONE; VINCRISTINE; VINCRISTINE SULFATE;

ALOPECIA; AMINOTRANSFERASE BLOOD LEVEL; ANALGESIA; ANEMIA; ASEPTIC NECROSIS; AUTONOMIC NEUROPATHY; BENIGN TUMOR; BLOOD TOXICITY; BODY WEIGHT DISORDER; BONE DISEASE; CARDIOTOXICITY; CATARACT; CENTRAL NERVOUS SYSTEM DISEASE; CORTICOSTEROID THERAPY; CUSHINGOID SYNDROME; DRUG ERUPTION; DRUG MECHANISM; EXCISION; EYE DISEASE; EYELID DISEASE; FEVER; FIBROSING ALVEOLITIS; FLU LIKE SYNDROME; GASTROINTESTINAL DISEASE; HEMORRHAGIC CYSTITIS; HUMAN; HYPERTENSION; HYPERURICEMIA; HYPOPHYSIS ADRENAL SYSTEM; IMMUNE DEFICIENCY; INFANT DISEASE; IRRITABILITY; LEUKOCYTOSIS; LIVER DYSFUNCTION; LOW LEVEL LASER THERAPY; MALAISE; MEDICAL DECISION MAKING; METHEMOGLOBINEMIA; NAUSEA; NECROSIS; NEUROTOXICITY; NEUTROPENIA; NONHUMAN; ORBIT; OSTEOPOROSIS; PARALYSIS; PERIPHERAL NEUROPATHY; PERSONALITY DISORDER; PHLEBITIS; REFLEX DISORDER; REVIEW; RISK ASSESSMENT; SIDE EFFECT; SKIN ATROPHY; SKIN HEMANGIOMA; SKIN NECROSIS; SKIN ULCER; SPASTICITY; STRIA; SURGICAL TECHNIQUE; TELANGIECTASIA; TREATMENT PLANNING; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR VOLUME; VASCULAR ENDOTHELIUM; VOMITING; WEIGHT GAIN; WOUND CARE; WOUND INFECTION;

ADRENAL CORTEX HORMONES; ANTINEOPLASTIC AGENTS; CYCLOPHOSPHAMIDE; HEMANGIOMA; HUMANS; INFANT; INFANT, NEWBORN; INTERFERON-ALPHA; SKIN NEOPLASMS; VINCRISTINE;

EID: 4544376399     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.5.9.1937     Document Type: Review

References (52)

1. JACOBS AH, WALTON RG: The incidence of birthmarks in the neonate. Pediatrics (1976) 58(2):218-222.
2. HOLMAHL K: Cutaneous hemangiomas in premature and mature infants. Acta Paediatr. (1955) 44:370-379.
3. JACOBS AH: Strawberry hemangiomas: the natural history of the untreated lesion. Calif. Med. (1957) 86:8-10.
4. DROLET BA, ESTERLY NB, FRIEDEN IJ: Hemangiomas in children. N. Engl. J. Med. (1999) 341:173-181.
5. ENJOLRAS O WASSEF M MAZOYER E et al.: Infants with Kasabach-Merritt syndrome do not have 'true' hemangiomas. J. Pediatr. (1997) 130:631-40.
6. SARKAR M, MULLIKEN JB, KOZAKEWICH HP, ROBERTSON RL, BURROWS PE: Thrombocytopenic coagulopathy (Kasabach-Merritt phenomenon) is associated with Kaposiform hemangioendothelioma and not with common infantile hemangioma. Plast. Reconstr. Surg. (1997) 100:1377-1386.
7. ENJOLRAS O, MULLIKEN JB, BOON LM, WASSEF M, KOZAKEWICH HP, BURROWS PE: Noninvoluting congenital hemangioma: a rare cutaneous vascular anomaly. Plast. Reconstr. Surg. (2001) 107:1647-1654.
8. NORTH PE, WANER M, MIZERACKI A, MIHM MC JR: GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas. Hum. Pathol. (2000) 31:11-22.
9. BOON LM, ENJOLRAS O, MULLIKEN JB: Congenital hemangioma: evidence of accelerated involution. J. Pediatr. (1996) 128:329-335.
10. BERENGUER B MULLIKEN JB ENJOLRAS O et al.: Rapidly Involuting Congenital Hemangioma: Clinical and Histopathologic Features. Pediatr. Dev. Pathol. (2003) 6(6):495-510.
11. FRIEDEN IJ, REESE V, COHEN D: PHACE Syndrome. The association of posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities. Arch. Dermatol. (1996) 132:307-311.
12. SLOAN GM, REINISCH JF, NICHTER LS, SABER WL, LEW K, MORWOOD DT: Intralesional corticosteroid therapy for infantile hemangiomas. Plast. Reconstr. Surg. (1989) 83:459-467.
13. REYE BA, VAZQUEZ-BOTET M, CAPO H: Intralesional steroids in cutaneous hemangioma. J. Dermatol. Surg. Oncol. (1989) 15:828-832.
14. KUSHNER BJ: Local steroid therapy in adnexal hemangioma. Ann. Ophthalmol. (1979) 11:1005-1009.
15. KUSHNER BJ: The treatment of periorbital infantile hemangioma with intralesional coeticosteroid. Plast. Reconstr. Surg. (1985) 76:517-524.
16. EGBERT JE, PAUL S, ENGEL WK, SUMMERS CG: High injection pressure during intralesional injection of corticosteroids into capillary hemangiomas. Arch. Ophthalmol. (2001) 119:677-683.
17. REYES BA, VAZQUEZ-BOTET M, CAPO H: Intralesional steroids in cutaneous hemangioma. J. Dermatol. Surg. Oncol. (1989) 15:828-832.
18. SUTULA FC, GLOVER AT: Eyelid necrosis following intralesional corticosteroid injection for capillary hemangioma. Ophthalmic Surg. (1987) 18:103-105.
19. SHORR N, SEIFF SR: Central retinal artery occlusion associated with periocular corticosteroid injection for juvenile hemangioma. Ophthalmic Surg. (1986) 17:229-231.
20. RUTTUM MS, ABRAMS GW, HARRIS GJ, ELLIS MK: Bilateral retinal embolization associated with intralesional corticosteroid injection for capillary hemangioma of infancy. J. Pediatr. Ophthalmol. Strabismus (1993) 30:4-7.
21. ZAREM HA, EDGERTON MT: Induced resolution of cavernous hemangiomas following prednisolone therapy. Plast. Reconstr. Surg. (1967) 39:76-83.
22. FOST NC, ESTERLY NB: Successful treatment of juvenile hemangiomas with prednisolone. J. Pediatr. (1968) 72:351-357.
23. SADAN N, WOLACH B: Treatment of hemangiomas of infants with high doses of prednisone. J. Pediatr. (1996) 128:141-146.
24. ENJOLRAS O, RICHE MC, MERLAND JJ, ESCANDE JP: Management of alarming hemangiomas in infancy: a review of 25 cases. Pediatrics. (1990) 85:491-498.
25. GANGOPADHYAY AN, SINHA CK, GOPAL SC, GUPTA DK, SAHOO SP, AHMAD M: Role of steroid in childhood haemangioma: a 10 years review. Int. Surg. (1997) 82:49-51.
26. ELSAS FJ, LEWIS AR: Topical treatment of periocular capillary hemangioma. J. Pediatr. Ophthalmol. Strabismus (1994) 31:153-156.
27. CRUZ OA, ZARNEGAR SR, MYERS SE: Treatment of periocular capillary hemangioma with topical clobetasol propionate. Ophthalmology (1995) 102:2012-2015.
28. LOUDON SE, POLLING JR, SIMONSZ HJ: A preliminary report about the relation between visual acuity increase and compliance in patching therapy for amblyopia. Strabismus (2002) 10:79-82.
29. BATTEGAY EJ: Angiogenesis: mechanistic insights, neovascular diseases and therapeutic prospects. J. Mol. Med. (1995) 73:333-346.
30. EZEKOWITZ RA, MULLIKEN JB, FOLKMAN J: Interferon alfa-2a therapy for life-threatening hemangiomas of infancy. N. Engl. J. Med. (1992) 326:1456-1463.
31. BAUMAN NM, BURKE DK, SMITH RJ: Treatment of massive or life-threatening hemangiomas with recombinant alpha(2a)-interferon. Otolaryngol. Head Neck Surg. (1997) 117:99-110.
32. CHANG E BOYD A NELSON CC et al.: Successful treatment of infantile hemangiomas with interferon-alpha-2b. J. Pediatr. Hematol. Oncol. (1997) 19:237-244.
33. RICKETTS RR, HATLEY RM, CORDEN BJ, SABIO H, HOWELL CG: Interferon-alpha-2a for the treatment of complex hemangiomas of infancy and childhood. Ann. Surg. (1994) 219(6):605-612.
34. BARLOW CF PRIEBE CJ MULLIKEN JB et al.: Spastic diplegia as a complication of interferon Alfa-2a treatment of hemangiomas of infancy. J. Pediatr. (1998) 132(3 Pt 1):527-530.
35. GREINWALD JH Jr, BURKE DK, BONTHIUS DJ, BAUMAN NM, SMITH RJ: An update on the treatment of hemangiomas in children with interferon alfa-2a. Arch. Otolaryngol. Head Neck Surg. (1999) 125(1):21-27.
36. BROWDER T, BUTTERFIELD CE, KRALING BM et al.: Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res. (2000) 60(7):1878-1886.
37. KLEMENT G BARUCHEL S RAK J et al.: Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity. J. Clin. Invest. (2000) 105(8):R15-R24.
38. BOEHM DK, KOBRINSKY NL: Treatment of cavernous hemangioma with vincristine. Ann. Pharmacother. (1993) 27:981.
39. ENJOLRAS O, BREVIERE GM, ROGER G et al.: [Vincristine treatment for function- and life-threatening infantile hemangioma]. Arch. Pediatr. (2004) 11:99-107.
40. FAWCETT SL, GRANT I, HALL PN, KELSALL AW, NICHOLSON JC: Vincristine as a treatment for a large haemangioma threatening vital functions. Br. J. Plast. Surg. (2004) 57(2):168-171.
41. PEREZ PAYAROLS J, PARDO MASFERRER J, GOMEZ BELLVERT C: Treatment of life-threatening infantile hemangiomas with vincristine. N. Engl. J. Med. (1995) 333(1):69.
42. MOORE J LEE M GARZON M et al.: Effective therapy of a vascular tumor of infancy with vincristine. J. Pediatr. Surg. (2001) 36(8):1273-1276.
43. HURVITZ SA, HURVITZ CH, SLONINSKY L, SANFORD MC: Successful treatment with cyclophosphamide of life-threatening diffuse hemangiomatosis involving the liver. J. Pediatr. Hematol. Oncol. (2000) 22:527-532.
44. STANLEY P, GEER GD, MILLER JH, GILSANZ V, LANDING BH, BOECHAT IM: Infantile hepatic hemangiomas. Clinical features, radiologic investigations, and treatment of 20 patients. Cancer (1989) 64(4):936-949.
45. MORELLI JG, TAN OT, YOHN JJ, WESTON WL: Treatment of ulcerated hemangiomas infancy; Arch. Pediatr. Adolesc Med. (1994) 148:1104-1105.
46. GARDEN JM, BAKUS AD, PALLER AS: Treatment of cutaneous hemangiomas by the flashlamp-pumped pulsed dye laser: prospective analysis. J. Pediatr. (1992) 120:555-560.
47. ASHINOFF R, GERONEMUS RG: Capillary hemangiomas and treatment with the flash lamp-pumped pulsed dye laser. Arch. Dermatol. (1991) 127(2):202-205.
48. ASHINOFF R, GERONEMUS RG: Failure of the flashlamp-pumped pulsed dye laser to prevent progression to deep hemangioma. Pediatr. Dermatol. (1993) 10:77-80.
49. SCHEEPERS JH, QUABA AA: Does the pulsed tunable dye laser have a role in the management of infantile hemangiomas? Observations based on 3 years' experience. Plast. Reconstr. Surg. (1995) 95(2):305-312.
50. BATTA K, GOODYEAR HM, MOSS C, WILLIAMS HC, HILLER L, WATERS R: Randomised controlled study of early pulsed dye laser treatment of uncomplicated childhood haemangiomas: results of a 1-year analysis. Lancet (2002) 360:521-527.
51. PITANGUY I, MACHADO BH, RADWANSKI HN, AMORIM NF: Surgical treatment of hemangiomas of the nose. Ann. Plast. Surg. (1996) 36:586-592.
52. DEANS RM, HARRIS GJ, KIVLIN JD: Surgical dissection of capillary hemangiomas. An alternative to intralesional corticosteroids. Arch. Ophthalmol. (1992) 110:1743-1747.