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Volumn 28, Issue 11, 2004, Pages 1125-1136

Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia: Part I. In vivo studies

Author keywords

acute myelogenous leukemia; AML; bcr abl positive leukemia; chronic myelogenous leukemia; chronic myelogenous leukemia in blast crisis; CML; CML blast crisis; CML BC; IMPDH; inosine monophosphate dehydrogenase; Ph' chromosome; Philadelphia chromosome

Indexed keywords

BCR ABL PROTEIN; INOSINE PHOSPHATE; OXIDOREDUCTASE; TIAZOFURIN;

EID: 4544366831     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2004.03.003     Document Type: Article
Times cited : (33)

References (38)
  • 1
    • 0037255947 scopus 로고    scopus 로고
    • Advanced-phase chronic myeloid leukemia
    • Cortes J., Kantarjian H. Advanced-phase chronic myeloid leukemia. Semin. Hematol. 40:2003;79-86
    • (2003) Semin. Hematol. , vol.40 , pp. 79-86
    • Cortes, J.1    Kantarjian, H.2
  • 2
    • 0037186915 scopus 로고    scopus 로고
    • Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
    • Kantarjian H., Sawyers C., Hochhaus A., Guilhot F., Schiffer C., Gambacorti-Passerini C., et al. International STI571 CML Study Group Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N. Engl. J. Med. 346:2002;645-652
    • (2002) N. Engl. J. Med. , vol.346 , pp. 645-652
    • Kantarjian, H.1    Sawyers, C.2    Hochhaus, A.3    Guilhot, F.4    Schiffer, C.5    Et Al., G.C.6
  • 4
    • 0028168106 scopus 로고
    • P210 bcr-abl confers overexpression of inosine monophosphate dehydrogenase: An intrinsic pathway to drug resistance mediated by oncogene
    • Gharehbaghi K., Burgess G.S., Collart F.R., Litz-Jackson S., Huberman E., Jayaram H.N., et al. p210 bcr-abl confers overexpression of inosine monophosphate dehydrogenase: an intrinsic pathway to drug resistance mediated by oncogene. Leukemia. 8:1994;1257-1263
    • (1994) Leukemia , vol.8 , pp. 1257-1263
    • Gharehbaghi, K.1    Burgess, G.S.2    Collart, F.R.3    Litz-Jackson, S.4    Huberman, E.5    Jayaram, H.N.6
  • 5
    • 0020034881 scopus 로고
    • 2-Beta-D-ribofuranosylthiazole-4-carboxamide, a novel potential antitumor agent for lung tumors and metastases
    • Robins R.K., Srivastava V.L., Narayanan L., Plowman L., Pauli K.D. 2-Beta-D-ribofuranosylthiazole-4-carboxamide, a novel potential antitumor agent for lung tumors and metastases. J. Med. Chem. 25:1982;107-108
    • (1982) J. Med. Chem. , vol.25 , pp. 107-108
    • Robins, R.K.1    Srivastava, V.L.2    Narayanan, L.3    Plowman, L.4    Pauli, K.D.5
  • 6
    • 0020550770 scopus 로고
    • Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties
    • Jayaram H.N., Ahluwalia G.S., Dion R.L., Gebeyehu G., Marquez V.E., Kelley J.A., et al. Conversion of 2-beta-D-ribofuranosylselenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase-inhibitory properties. Biochem. Pharmacol. 32:1983;2633-2636
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 2633-2636
    • Jayaram, H.N.1    Ahluwalia, G.S.2    Dion, R.L.3    Gebeyehu, G.4    Marquez, V.E.5    Kelley, J.A.6
  • 8
    • 0022403035 scopus 로고
    • Pediatric phase I trial and pharmacokinetics of Tiazofurin (NSC 286193)
    • Balis F.M., Lange B.L., Packer R.J., et al. Pediatric phase I trial and pharmacokinetics of Tiazofurin (NSC 286193). Cancer Res. 45:1985;5169-5172
    • (1985) Cancer Res. , vol.45 , pp. 5169-5172
    • Balis, F.M.1    Lange, B.L.2    Packer, R.J.3
  • 11
    • 0030499040 scopus 로고    scopus 로고
    • Biochemically targeted therapy of refractory leukemia and myeloid blast crisis of chronic granulocytic leukemia with Tiazofurin, a selective blocker of inosine 5′-phosphate dehydrogenase activity
    • Tricot G., Weber G. Biochemically targeted therapy of refractory leukemia and myeloid blast crisis of chronic granulocytic leukemia with Tiazofurin, a selective blocker of inosine 5′-phosphate dehydrogenase activity. Anticancer Res. 16:1996;3341-3347
    • (1996) Anticancer Res. , vol.16 , pp. 3341-3347
    • Tricot, G.1    Weber, G.2
  • 12
    • 0023241646 scopus 로고
    • Hematologic and biochemical action of Tiazofurin (NSC 286193) in a case of refractory acute myeloid leukemia
    • Tricot G.J., Jarayam H.N., Nichols C.R., Pennington K., Lapis E., Weber G., et al. Hematologic and biochemical action of Tiazofurin (NSC 286193) in a case of refractory acute myeloid leukemia. Cancer Res. 47:1987;4988-4991
    • (1987) Cancer Res. , vol.47 , pp. 4988-4991
    • Tricot, G.J.1    Jarayam, H.N.2    Nichols, C.R.3    Pennington, K.4    Lapis, E.5    Weber, G.6
  • 13
    • 0024394730 scopus 로고
    • Biochemically directed therapy of leukemia with Tiazofurin, a selective blocker of inosine 5′-monophosphate dehydrogenase activity
    • Tricot G.J., Jarayam H.N., Lapis E., Natsumeda Y., Nichols C.R., Kneebone P., et al. Biochemically directed therapy of leukemia with Tiazofurin, a selective blocker of inosine 5′-monophosphate dehydrogenase activity. Cancer Res. 49:1989;3696-3701
    • (1989) Cancer Res. , vol.49 , pp. 3696-3701
    • Tricot, G.J.1    Jarayam, H.N.2    Lapis, E.3    Natsumeda, Y.4    Nichols, C.R.5    Kneebone, P.6
  • 14
    • 4544366177 scopus 로고    scopus 로고
    • Dr. J Mel Sorensen, Investigational Drug Branch, CTEP, DCT, NCI, personal communication.
    • Dr. J Mel Sorensen, Investigational Drug Branch, CTEP, DCT, NCI, personal communication.
  • 15
    • 0021084824 scopus 로고
    • Purine metabolism in myeloid precursor cells during maturation: Studies with the HL-60 cell line
    • Lucas D.L., Webster H.K., Wright D.G. Purine metabolism in myeloid precursor cells during maturation: studies with the HL-60 cell line. J. Clin. Invest. 72:1983;1889-1900
    • (1983) J. Clin. Invest. , vol.72 , pp. 1889-1900
    • Lucas, D.L.1    Webster, H.K.2    Wright, D.G.3
  • 16
    • 0020509542 scopus 로고
    • Induced maturation of the human promyelocytic leukemia cell line, HL-60, by 2-beta-D-ribofuranosylselenazole-4-carboxamide
    • Lucas D.L., Robins R.K., Knight R.D., Wright D.G. Induced maturation of the human promyelocytic leukemia cell line, HL-60, by 2-beta-D- ribofuranosylselenazole-4-carboxamide. Biochem. Biophys. Res. Commun. 115:1983;971-980
    • (1983) Biochem. Biophys. Res. Commun. , vol.115 , pp. 971-980
    • Lucas, D.L.1    Robins, R.K.2    Knight, R.D.3    Wright, D.G.4
  • 17
    • 0023149035 scopus 로고
    • A role for guanine ribonucleotides in the regulation of myeloid cell maturation
    • Wright D.G. A role for guanine ribonucleotides in the regulation of myeloid cell maturation. Blood. 69:1987;334-338
    • (1987) Blood , vol.69 , pp. 334-338
    • Wright, D.G.1
  • 19
    • 0022575008 scopus 로고
    • Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5′-phosphate dehydrogenase
    • Sokoloski J.A., Blair O.C., Sartorelli A.C. Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5′-phosphate dehydrogenase. Cancer Res. 46:1986;2314-2319
    • (1986) Cancer Res. , vol.46 , pp. 2314-2319
    • Sokoloski, J.A.1    Blair, O.C.2    Sartorelli, A.C.3
  • 20
    • 0024434797 scopus 로고
    • Induction of erythroid differentiation in K562 cells by inhibitors of inosine monophosphate dehydrogenase
    • Yu J., Lemas V., Page J.D., Connor J.D., Yu A.L. Induction of erythroid differentiation in K562 cells by inhibitors of inosine monophosphate dehydrogenase. Cancer Res. 49:1988;5555-5560
    • (1988) Cancer Res. , vol.49 , pp. 5555-5560
    • Yu, J.1    Lemas, V.2    Page, J.D.3    Connor, J.D.4    Yu, A.L.5
  • 21
    • 0003922530 scopus 로고
    • Induction of erythroid differentiation and modulation of gene expression by Tiazofurin in K-562 leukemia cells
    • Olah E., Natsumeda Y., Ikegami T., Kote Z., Horanyi M., Szelenyi J., et al. Induction of erythroid differentiation and modulation of gene expression by Tiazofurin in K-562 leukemia cells. Proc. Natl. Acad. Sci. U.S.A. 85:1988;6533-6537
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 6533-6537
    • Olah, E.1    Natsumeda, Y.2    Ikegami, T.3    Kote, Z.4    Horanyi, M.5    Szelenyi, J.6
  • 22
    • 0023790909 scopus 로고
    • Effects of Tiazofurin on protooncogene expression during HL-60 cell differentiation
    • Kharbanda S.M., Sherman M.L., Spriggs D.R., Kufe D.W. Effects of Tiazofurin on protooncogene expression during HL-60 cell differentiation. Cancer Res. 48:1988;5965-5968
    • (1988) Cancer Res. , vol.48 , pp. 5965-5968
    • Kharbanda, S.M.1    Sherman, M.L.2    Spriggs, D.R.3    Kufe, D.W.4
  • 23
    • 0025138399 scopus 로고
    • Cell differentiation and altered IMP dehydrogenase expression induced in human T-lymphoblastoid leukemia cells by mycophenolic acid and Tiazofurin
    • Kiguchi K., Collart F.R., Henning-Chubb C., Huberman E. Cell differentiation and altered IMP dehydrogenase expression induced in human T-lymphoblastoid leukemia cells by mycophenolic acid and Tiazofurin. Exp. Cell Res. 187:1990;47-53
    • (1990) Exp. Cell Res. , vol.187 , pp. 47-53
    • Kiguchi, K.1    Collart, F.R.2    Henning-Chubb, C.3    Huberman, E.4
  • 24
    • 0025882795 scopus 로고
    • Induction of HL60 cell differentiation by Tiazofurin and its analogues: Characterization and efficacy
    • Goldstein B.M., Leary J.F., Farley B.A., Marquez V.E., Levy P.C., Rowley P.T. Induction of HL60 cell differentiation by Tiazofurin and its analogues: characterization and efficacy. Blood. 78:1991;593-598
    • (1991) Blood , vol.78 , pp. 593-598
    • Goldstein, B.M.1    Leary, J.F.2    Farley, B.A.3    Marquez, V.E.4    Levy, P.C.5    Rowley, P.T.6
  • 26
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human peripheral blood
    • Boyum A. Isolation of mononuclear cells and granulocytes from human peripheral blood. Scand. J. Clin. Lab. Invest. 21(Suppl. 97):1968;77-89
    • (1968) Scand. J. Clin. Lab. Invest. , vol.21 , Issue.SUPPL. 97 , pp. 77-89
    • Boyum, A.1
  • 27
    • 0026463092 scopus 로고
    • Assay method for monitoring the inhibitory effects of antimetabolites on the activity of inosinate dehydrogenase in intact human CEM lymphocytes
    • Balzarini J., De Clercq E. Assay method for monitoring the inhibitory effects of antimetabolites on the activity of inosinate dehydrogenase in intact human CEM lymphocytes. Biochem. J. 287:1992;785-790
    • (1992) Biochem. J. , vol.287 , pp. 785-790
    • Balzarini, J.1    De Clercq, E.2
  • 28
    • 0026055099 scopus 로고
    • Regulation of IMP dehydrogenase gene expression by its end products, guanine ribonucleotides
    • Glesne D.A., Collart F.R., Huberman E. Regulation of IMP dehydrogenase gene expression by its end products, guanine ribonucleotides. Mol. Cell Biol. 11:1991;5417-5425
    • (1991) Mol. Cell Biol. , vol.11 , pp. 5417-5425
    • Glesne, D.A.1    Collart, F.R.2    Huberman, E.3
  • 29
    • 0025961794 scopus 로고
    • Expression of human IMP dehydrogenase types I and II in Escherichia coli and distribution in human normal lymphocytes and leukemic cell lines
    • Konno Y., Natsumeda Y., Nagai M., Yamaji Y., Ohno S., Suzuki K., et al. Expression of human IMP dehydrogenase types I and II in Escherichia coli and distribution in human normal lymphocytes and leukemic cell lines. J. Biol. Chem. 266:1991;506-509
    • (1991) J. Biol. Chem. , vol.266 , pp. 506-509
    • Konno, Y.1    Natsumeda, Y.2    Nagai, M.3    Yamaji, Y.4    Ohno, S.5    Suzuki, K.6
  • 30
    • 0026378294 scopus 로고
    • Selective up-regulation of type II inosine 5′-monophosphate dehydrogenase messenger RNA expression in human leukemias
    • Nagai M., Natsumeda Y., Konno Y., Hoffman R., Irino S., Weber G Selective up-regulation of type II inosine 5′-monophosphate dehydrogenase messenger RNA expression in human leukemias. Cancer Res. 51:1991;3886-3890
    • (1991) Cancer Res. , vol.51 , pp. 3886-3890
    • Nagai, M.1    Natsumeda, Y.2    Konno, Y.3    Hoffman, R.4    Irino, S.5    Weber, G.6
  • 31
    • 0036464594 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Evolving therapeutic strategies
    • Tallman M.S., Nabhan C., Feusner J.H., Rowe J.M. Acute promyelocytic leukemia: evolving therapeutic strategies. Blood. 99:2002;759-767
    • (2002) Blood , vol.99 , pp. 759-767
    • Tallman, M.S.1    Nabhan, C.2    Feusner, J.H.3    Rowe, J.M.4
  • 32
    • 0025087579 scopus 로고
    • Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T- and B-cell purine synthesis
    • Morris R.E., Hoyt E.G., Murphy M.P., Eugui E.M., Allison A.C. Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T- and B-cell purine synthesis. Transpl. Proc. 22:1990;1659-1662
    • (1990) Transpl. Proc. , vol.22 , pp. 1659-1662
    • Morris, R.E.1    Hoyt, E.G.2    Murphy, M.P.3    Eugui, E.M.4    Allison, A.C.5
  • 34
    • 0029115531 scopus 로고
    • Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group
    • Sollinger H.W. Mycophenolate mofetil for the prevention of acute rejection in primary cadaveric renal allograft recipients. U.S. Renal Transplant Mycophenolate Mofetil Study Group. Transplantation. 60:1995;225-232
    • (1995) Transplantation , vol.60 , pp. 225-232
    • Sollinger, H.W.1
  • 35
    • 3242756176 scopus 로고    scopus 로고
    • High dose Imatinib (STI571, Gleevec) provides durable long-term outcomes for patients with chronic myeloid leukemia (CML) in accelerated phase (AP) or myeloid blast crisis (BC): Follow-up of the phase-II studies
    • Talpaz M., Goldman J.M., Sawyers C.L., Hochhaus A., Silver R.T., Smith B.D., et al. International STI571 Study Group High dose Imatinib (STI571, Gleevec) provides durable long-term outcomes for patients with chronic myeloid leukemia (CML) in accelerated phase (AP) or myeloid blast crisis (BC): follow-up of the phase-II studies. Blood. 102(11):2003;905a
    • (2003) Blood , vol.102 , Issue.11
    • Talpaz, M.1    Goldman, J.M.2    Sawyers, C.L.3    Hochhaus, A.4    Silver, R.T.5    Et Al., D.S.B.6
  • 36
    • 0022654946 scopus 로고
    • Therapeutic synergism of Tiazofurin and selected antitumor drugs against sensitive and resistant P388 leukemia in mice
    • Harrison S.D., O'Dwyer P.J., Trades M.W. Therapeutic synergism of Tiazofurin and selected antitumor drugs against sensitive and resistant P388 leukemia in mice. Cancer Res. 46:1986;3396-3400
    • (1986) Cancer Res. , vol.46 , pp. 3396-3400
    • Harrison, S.D.1    O'Dwyer, P.J.2    Trades, M.W.3
  • 37
    • 0027656137 scopus 로고
    • Synergistic action of taxol and Tiazofurin in human ovarian, pancreatic and lung carcinoma cells
    • Taniki T., Prajda N., Monden Y., Weber G. Synergistic action of taxol and Tiazofurin in human ovarian, pancreatic and lung carcinoma cells. Cancer Biochem. Biophys. 13:1993;295-302
    • (1993) Cancer Biochem. Biophys. , vol.13 , pp. 295-302
    • Taniki, T.1    Prajda, N.2    Monden, Y.3    Weber, G.4
  • 38
    • 0028339458 scopus 로고
    • Synergistic action of taxol with Tiazofurin and methotrexate in human breast cancer cells: Schedule-dependence
    • Yeh Y.A., Olah E., Wendel J.J., Sledge G.W. Jr., Weber G. Synergistic action of taxol with Tiazofurin and methotrexate in human breast cancer cells: schedule-dependence. Life Sci. 54:1994;431-435
    • (1994) Life Sci. , vol.54 , pp. 431-435
    • Yeh, Y.A.1    Olah, E.2    Wendel, J.J.3    Sledge Jr., G.W.4    Weber, G.5


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