Treatment of T3 and T4 anal carcinoma with combined chemoradiation and interstitial 192Ir implantation: A 10-year experience

Brachytherapy

Volumn 3, Issue 2, 2004, Pages 95-100

  Hwang, Julie M ^a,b   Rao, Aroor R ^a   Cosmatos, Harry A ^a   Wang, Ricardo ^a   Kaptein, John S ^a   Kagan, Robert A ^a   Hsiang, Jim Y ^a   Tome, Michael ^a  

^a KAISER PERMANENTE   (United States)

^b Southern California Permanente Group   (United States)

Author keywords

Anal cancer; Brachytherapy; Chemoradiation; Combined modality; Implant; Interstitial; Radiation

Indexed keywords

FLUOROURACIL; IRIDIUM 192; MITOMYCIN C;

ADULT; AGED; ANUS CARCINOMA; ANUS FISTULA; ARTICLE; BLOOD TOXICITY; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; DIARRHEA; FECES INCONTINENCE; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; HUMAN; IMPLANTATION; LEUKOCYTE; MALE; METASTASIS; PRIORITY JOURNAL; PROCTITIS; RADIATION DOSE; SKIN MANIFESTATION; SMALL INTESTINE OBSTRUCTION; ULCER;

ADULT; AGED; AGED, 80 AND OVER; ANTIBIOTICS, ANTINEOPLASTIC; ANUS NEOPLASMS; BRACHYTHERAPY; FEMALE; FLUOROURACIL; HUMANS; IRIDIUM RADIOISOTOPES; MALE; MIDDLE AGED; MITOMYCIN;

EID: 4544360620     PISSN: 15384721     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brachy.2004.06.003     Document Type: Article

References (19)

1. American Cancer Society. Cancer facts and figures 2004. Available at: http://www.cancer.org/docroot/home/index.asp Accessed July 30, 2004.
2. D.B. Frost, P.C. Richards, and E.D. Montague Epidermoid cancer of the anorectum Cancer 53 1984 1285 1293
3. L. Leichman, N. Nigro, and V.K. Vaitkevicius Cancer of the anal canal: Model for preoperative adjuvant combined modality therapy Am J Med 75 1985 211 215
4. H. Bartelink Epidermoid anal cancer: Results from UKCCCR randomized trial of radiotherapy alone versus radiotherapy, 5-fluoruracil, and mitomycin Lancet 348 1996 1049 1054
5. UKCCCR Anal Cancer Trial Working Party, F. Roelofsen, and F. Eschwege Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: Results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups J Clin Oncol 15 1997 2040 2049
6. B. Sichy, R.L.S. Doggett, and J.M. Krall Definitive irradiation and chemotherapy for radiosensitization in management of anal carcinoma: Interim report on Radiation Therapy Oncology Group Study No. 8314 J Natl Cancer Inst 81 1989 850 856
7. M. Flam, J. Madhu, and T.F. Pajak Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: Results of a phase III randomized intergroup study J Clin Oncol 14 1996 2527 2539
8. M. John, T. Pajak, and M. Flam Dose escalation in chemoradiation for anal cancer: Preliminary results of RTOG 92-08 Cancer J Sci Am 2 1996 205 211
9. J.A. Martenson, S.R. Lipsitz, and M. Lefkopoulou Results of combined modality therapy for patients with anal cancer (E7283) Cancer 76 1995 1731 1736
10. D.E. Smith, K.H. Shah, and A.R. Rao Cancer of the anal canal: Treatment with chemotherapy and low-dose radiation therapy Radiology 191 1994 569 572
11. A.J. Olch RSNA categorical course in brachytherapy physics 1997 RSNA Publications Oak Brook, IL p. 91-97
12. Ajani J, Pederson J, Gunderson L, et al. Radiation Therapy Oncology Group. 98-11. A phase III randomized study of 5-flurouracil, mitomycin-c, and radiotherapy versus 5-flurouracil, cisplatin, and radiotherapy in carcinoma of the anal canal. Available at: http://rtog.org/members/protocols/98-11/9811.pdf. Accessed July 30, 2004.
13. J. Papillon, J.F. Montbarbon, and J.P. Gerard Interstitial curietherapy in the conservative treatment of anal and rectal cancers Int J Radiat Oncol Biol Phys 17 1989 1161 1169
14. A.A. Puthwala, A.M.N. Syed, and T.C. Gates Definitive treatment of extensive anorectal carcinoma by external and interstitial irradiation Cancer 50 1982 1746 1750
15. N.Y.K. Kin, J. Pigneux, and H. Auvray Our experience of conservative treatment of anal canal carcinoma combining external irradiation and interstitial implant: 32 cases treated between 1973 and 1982 Int J Radiat Oncol Biol Phys 14 1987 253 259
16. D. Peiffert, P. Bey, and M. Pernot Conservative treatment by irradiation of epidermoid cancers of the anal canal: Prognostic factors of tumoral control and complications Int J Radiat Oncol Biol Phys 37 1997 313 324
17. 192Ir implantation combined with external radiotherapy in anal cancer: Ten years experience Int J Radiat Oncol Biol Phys 40 1998 575 581
18. J.A. Ajani, C.H. Carrasco, and D.E. Jackson Combination of cisplatinum and fluropyrimidine chemotherapy effective against liver metastases from cancer of anal canal Am J Med 87 1989 221 224
19. R.W. Carey Regression of pulmonary metastases from cloacogenic cancer after cisplatinum/5-fluoruracil treatment J Clin Gastroenterol 6 1984 257 259