Hemorrhagic shock resuscitation with an artificial oxygen carrier, hemoglobin vesicle, maintains intestinal perfusion and suppresses the increase in plasma tumor necrosis factor-α

ASAIO Journal

Volumn 50, Issue 5, 2004, Pages 458-463

  Yoshizu, Akira ^a   Izumi, Yotaro ^a   Park, Sungick ^b   Sakai, Hiromi ^b   Takeoka, Shinji ^b   Horinouchi, Hirohisa ^a   Ikeda, Eiji ^a   Tsuchida, Eishun ^b   Kobayashi, Koichi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; HEMODYNAMICS; OXYGEN; PLASMAS; PROTEINS; TUMORS;

HEMORRHAGIC SHOCK; INFLAMMATORY RESPONSE; INTESTINAL PERFUSION; TUMOR NECROSIS FACTOR (TNF);

HEMOGLOBIN;

ALBUMIN; HEMOGLOBIN; OXYGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ERYTHROCYTE; HEMODYNAMICS; HEMORRHAGIC SHOCK; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; INTESTINE PERFUSION; MALE; NONHUMAN; OXYGEN TRANSPORT; PARAMETER; RABBIT; RAT; RESUSCITATION; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ANIMALS; BLOOD SUBSTITUTES; HEMOGLOBINS; INTESTINAL MUCOSA; MALE; RABBITS; RATS; SHOCK, HEMORRHAGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4544360318     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MAT.0000136508.51676.EF     Document Type: Article

References (19)

1. Tsuchida E: Blood Substitutes: Present and Future Perspectives. Amsterdam: Elsevier, 1998.
2. Chang TMS: Blood Substitutes: Principles, Methods, Products, and Clinical Trials. Basel: Karger, 1997.
3. 2 carriers determine constriction of resistance arteries and hypertension. Am J Physiol Heart Circ Physiol 279: H908-915, 2000.
4. Goda N, Suzuki K, Naito M, et al: Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation. J Clin Invest 101: 604-612, 1998.
5. 2 reaction and lipid peroxidation. Bioconjug Chem 13: 1302-1308, 2002.
6. Izumi Y, Sakai H, Hamada K, et al: Physiologic responses to exchange transfusion with Hemoglobin Vesicles as an artificial oxygen carrier in anesthetized rats: changes in mean arterial pressure and renal cortical oxygen tension. Crit Care Med 24: 1869-1873, 1996.
7. Izumi Y, Sakai H, Takeoka S, et al: Evaluation of the capabilities of a hemoglobin vesicle as an artificial oxygen carrier in a rat exchange transfusion model. ASAIO J 43: 289-297, 1997.
8. Kobayashi K, Izumi Y, Yoshizu A, et al: The oxygen carrying capability of hemoglobin vesicles evaluated in rat exchange transfusion models. Artif Cells Blood Substit Immobil Biotechnol 25: 357-366, 1997.
9. 2 carrier, evaluated in a rat hemorrhagic shock model. Artif Blood 5: 18-22, 1997.
10. Sakai H, Takeoka S, Wettstein R, Tsai AG, lntaglietta M, Tsuchida E: Systemic and microvascular responses to the hemorrhagic shock and resuscitation with Hb-vesicles. Am J Physiol Heart Circ Physiol 283: H1191-H1199, 2002.
11. 2 extraction in the dog. J Appl Physiol 63: 387-394, 1987.
12. Carrico CJ, Meakins JL, Marshall JC, Fry D, Maier RV: Multiple-organ-failure syndrome. Arch Surg 121: 196-208, 1986.
13. Sori AJ, Rush BF Jr, Lysz TW, Smith S, Machiedo GW: The gut as source of sepsis after hemorrhagic shock. Am J Surg 155: 187-192, 1988.
14. Sakai H, Takeoka S, Park SI: Surface-modification of hemoglobin vesicles with polyethyleneglycol and effects on aggregation, viscosity, and blood flow during 90%-exchange transfusion in anesthetized rats. Bioconjugate Chem 8: 15-22, 1997.
15. Sakai H, Masada Y, Takeoka S, Tsuchida E: Characteristics of bovine hemoglobin for the potential source of hemoglobin-vesicles as an artificial oxygen carrier. J Biochem 131: 611-617, 2002.
16. Sakai H, Takeoka S, Yokohama H, Seino Y, Nishide H, Tsuchida E: Purufication of concentrated Hb using organic solvent and heat treatment. Protein Expression Purif 4: 563-569, 1993.
17. Tamion F, Richard V, Lyoumi S: Gut ischemia and mesenteric synthesis of inflammatory cytokines after hemorrhagic or endotoxic shock. Am J Physiol 273: G314-321, 1997.
18. Nordin A, Makisalo H, Mildh L, Hockerstedt K: Gut intramucosal pH as an early indicator of effectiveness of therapy for hemorrhagic shock. Crit Care Med 26: 1110-1117, 1998.
19. Tani T, Fujino M, Hanasawa K, Shimizu T, Endo Y, Kodama M: Bacterial translocation and tumor necrosis factor-alpha gene expression in experimental hemorrhagic shock. Crit Care Med 28: 3705-3709, 2000.