Does haemodilution produce a hypercoagulable state?

Thrombosis and Haemostasis

Volumn 92, Issue 3, 2004, Pages 670-671

  Kretschmer, Volker ^a   Daraktchiev, Anton ^a   Karger, Ralf ^a  

^a UNIVERSITY HOSPITAL MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHLORIDE;

AMPLITUDE MODULATION; APHERESIS; BLEEDING TIME; BLOOD CLOTTING TIME; HEMATOCRIT; HEMODILUTION; HEMOSTASIS; HUMAN; HYPERCOAGULABILITY; IN VITRO STUDY; IN VIVO STUDY; LETTER; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; REACTION TIME; THROMBOELASTOGRAPHY;

EID: 4544355940     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613741     Document Type: Letter

References (14)

1. Ruttmann TG. Haemodilution enhances coagulation (Editorial). Br J Anaesth 2002; 88: 470-2.
2. Ruttmann TG, James MFM, Viljoen JF. Haemodilution induces a hypercoagulable state. Br J Anaesth 1996; 76: 412-4.
3. Ruttmann TG, James MFM, Aronson I. In vivo investigation into the effects of haemodilution with hydroxyethyl starch (200/0.5) and normal saline on coagulation. Br J Anaesth 1998; 80: 612-6.
4. Ng KFJ, Lam CCK, Chan LC. In vivo effect of haemodilution with saline on coagulation: a randomized controlled trial. Br J Anaesth 2002; 88: 475-80.
5. Iselin BM, Willimann PF, Seifert B, et al. Isolated reduction of haematocrit does not compromise in vitro blood coagulation. Br J Anaesth 2001; 87: 246-9.
6. Hellem AJ, Borchgrevink CF, Ames SB. The role of red cells in haemostasis: the relation between haematocrit, bleeding time and platelet adhesiveness. Br J Haematol 1961; 7: 42-50.
7. Fernandez F, Goudable C, Sie PT-TH, et al. Low haematocrit and prolonged bleeding time in uraemic patients: effect of red cell transfusion. Br J Haematol 1985; 59: 139-48.
8. Valeri CR, Cassidy G, Pivacek LE, et al. Anemia-induced increase in the bleeding time: implications for treatment of nonsurgical blood loss. Transfusion 2001; 41: 977-83.
9. Fries D, Innerhofer P, Klingler A, et al. The effect of the combined administration of colloids and lactated Ringer's solution on the coagulation system: an in vitro study using thrombelastograph® coagulation analysis (ROTEG®). Anesth Analg 2002; 94: 1280-7.
10. Innerhofer P, Fries D, Margreiter J, et al. The effects of perioperatively administered colloids and crystalloids on primary platelet-mediated hemostasis and clot formation. Anesth Analg 2002; 95: 858-65.
11. Kratzer MA, Born GV. Simulation of primary haemostasis in vitro. Haemostasis 1985; 15: 357-62.
12. Kretschmer V, Weippert-Kretschmer M. Determination and treatment of disorders of primary hemostasis - experience with routine application of the in vitro bleeding test. Hämostaseologie 1999; 19: 168-75.
13. Innerhofer P, Fries D, Klingler A, et al. The effect of haemodilution on coagulation (Letter). Br J Anaesth 2003; 90: 809-10.
14. Fries D, Streif W, Margreiter J, et al. The effects of perioperatively administered crystalloids and colloids on concentrations of molecular markers of activated coagulation and fibrinolysis. Blood Coagul Fibrinolysis 2004; 15: 213-9.