Gene delivery of 1-caldesmon protects cytoskeletal cell membrane integrity against adenovirus infection independently of myosin ATPase and actin assembly

American Journal of Physiology - Cell Physiology

Volumn 287, Issue 4 56-4, 2004, Pages

  Haxhinasto, Kari ^a   Kamath, Anant ^a   Blackwell, Ken ^a   Bodmer, James ^c   Van Heukelom, Jon ^a   English, Anthony ^b   Bai, Er Wei ^c   Moy, Alan B ^a,d  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c IA United States   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

Adhesion; Computational modeling; Focal contact; Motility; Quantitation

Indexed keywords

ACTIN; CALDESMON; CYTOCHALASIN D; CYTOSKELETON PROTEIN; MEMBRANE PROTEIN; MYOSIN ADENOSINE TRIPHOSPHATASE; TRYPTOPHAN; VINCULIN; CALMODULIN BINDING PROTEIN; MYOSIN;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MEMBRANE; CELL PROTECTION; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; DRUG EFFICACY; DRUG SAFETY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; MOLECULAR MECHANICS; MOLECULAR WEIGHT; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; VIRUS INFECTION; WILD TYPE; WOUND CLOSURE; ANIMAL; BIOLOGICAL MODEL; CELL LINE; ELECTRIC CAPACITANCE; FIBROBLAST; GENE THERAPY; GENE TRANSFER; GENETICS; METABOLISM; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY;

ADENOVIRIDAE; ANIMALIA; AVES; DNA VIRUSES;

ACTINS; ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; CALMODULIN-BINDING PROTEINS; CELL ADHESION; CELL LINE; CELL MEMBRANE; CYTOSKELETON; ELECTRIC CAPACITANCE; FIBROBLASTS; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; MODELS, BIOLOGICAL; MYOSINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION;

EID: 4544354233     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00530.2003     Document Type: Article

References (50)

1. Adelstein R. Myosin phosphorylation, cell motility and smooth muscle contraction. Trends Biochem Sci 3: 27-30, 1978.
2. Adelstein R and Conti M. Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity. Nature 256: 597-598, 1975.
3. 2+, cAMP, and changes in myosin phosphorylation during contraction of smooth muscle. Am J Physiol Cell Physiol 245: C255-C270, 1983.
4. Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, and Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 271: 20246-20249, 1996.
5. Bearer EL and Satpute-Krishnan P. The role of the cytoskeleton in the life cycle of viruses and intracellular bacteria: tracks, motors, and polymerization machines. Curr Drug Targets Infect Disord 2: 247-264, 2002.
6. Belisle B and Abo A. N-formyl peptide receptor ligation induces rac-dependent actin reorganization through Gβγ subunits and class Ia phosphoinositide 3-kinases. J Biol Chem 275: 26225-26232, 2000.
7. Bodmer J, Van Engelenhoven J, Reyes G, Kamath A, Shasby D, and Moy A. Isometric tension in cultured endothelial cells: new technical aspects. Microvasc Res 53: 261-271, 1997.
8. Brown MT, McBride KM, Baniecki ML, Reich NC, Marriott G, and Mangel WF. Actin can act as a cofactor for a viral proteinase in the cleavage of the cytoskeleton. J Biol Chem 277: 46298-46303, 2002.
9. Carson M, Shasby S, Lind S, and Shasby DM. Histamine, actin-gelsolin binding and polyphosphoinositides in human umbilical vein endothelial cells. Am J Physiol Lung Cell Mol Physiol 263: L664-L669, 1992.
10. Carson M, Shasby S, and Shasby DM. Histamine and inositol phosphate accumulation in endothelium: cAMP and a G protein. Am J Physiol Lung Cell Mol Physiol 257: L259-L264, 1989.
11. Coomber BL. Cytoskeleton in TFG-β- and bFGF-modulated endothelial monolayer repair. Exp Cell Res 194: 42-47, 1991.
12. Daniel J, Molish I, and Holmsen H. Myosin phosphorylation in intact platelets. J Biol Chem 256: 7510-7514, 1981.
13. Eberle M, Traynor-Kaplan AE, Sklar LA, and Norgauer, J. Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils? J Biol Chem 265: 16725-16728, 1990.
14. Eckes B, Colucci-Guyon E, Smola H, Nodder S, Babinet C, Krieg T, and Martin P. Impaired wound healing in embryonic and adult mice lacking vimentin. J Cell Sci 113: 2455-2462, 2000.
15. Elliott G and O'Hare P. Intercellular trafficking and protein delivery by a herpes virus structural protein. Cell 88: 223-233, 1997.
16. Fasbender A, Lee JH, Walters RW, Moninger TO, Zabner J, and Welsh MJ. Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo. J Clin Invest 102: 184-193, 1998.
17. Fishkind DJ, Cao L, and Wang Y. Microinjection of the catalytic fragment of myosin light chain kinase into dividing cells: effects on mitosis and cytokinesis. J Cell Biol 114: 967-975, 1991.
18. Gandhi S, Lorimer DD, and de Lanerolle P. Expression of a mutant myosin light chain that cannot be phosphorylated increases paracellular permeability. Am J Physiol Renal Physiol 111: F214-F221, 1997.
19. Giaever I and Keese CR. Micromotion of mammalian cells measured electrically. Proc Natl Acad Sci USA 88: 7896-7900, 1991.
20. Giaever I and Keese CR. Monitoring fibroblast behavior in tissue culture with an applied electric field. Proc Natl Acad Sci USA 81: 3761-3764, 1984.
21. Grinnell F. Fibroblasts, myofibroblast, and wound contraction. J Cell Biol 124: 401-404, 1994.
22. Hecht G, Pestic L, Nikcevic G, Koutsouris A, Tripuraneni J, Lorimer DD, Nowak G, Guerriero V Jr, Elson EL, and Lanerolle PD. Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability. Am J Physiol Cell Physiol 271: C1678-C1684, 1996.
23. Helfman DM, Levy ET, Berthier C, Shtutman M, Riveline D, Grosheva I, Lachish-Zalait A, Elbaum M, and Bershadsky AD. Caldesmon inhibits nonmuscle cell contractility and interferes with the formation of focal adhesions. Mol Biol Cell 10: 3097-3112, 1999.
24. Holwell TA, Schweitzer SC, and Evans RM. Tetracycline regulated expression of vimentin in fibroblasts derived from vimentin null mice. J Cell Sci 110: 1947-1956, 1997.
25. Imaizumi T, Jean-Louis F, Dubertret ML, Bailly C, Cicurel L, Petchot-Bacque JP, and Dubertret L. Effect of human basic fibroblast growth factor on fibroblast proliferation, cell volume, collagen lattice contraction: in comparison with acidic type. J Dermatol Sci 11: 134-141, 1996.
26. Iyengar S, Hildreth JE, and Schwartz DH. Actin-dependent receptor colocalization required for human immunodeficiency virus entry into host cells. J Virol 72: 5251-5255, 1998.
27. Jackson P and Bellett AJ. Relationship between organization of the actin cytoskeleton and the cell cycle in normal and adenovirus-infected rat cells. J Virol 63: 311-318, 1989.
28. Kawamoto S, Bengur A, Sellers J, and Adelstein R. In situ phosphorylation of human platelet myosin heavy and light chains by protein kinase C. J Biol Chem 264: 2258-2265, 1989.
29. Kimura K, Ito M, Amano M, Fukata C, Nakafuku K, Iwamatsu A, and Kaibuchi K. Regulation of myosin phosphatase by Rho and Rho-associated kinase. Science 273: 245-248, 1996.
30. Lash JA, Sellers JR, and Hathaway DR. The effects of caldesmon on smooth muscle heavy actomeromyosin ATPase activity and binding of heavy meromyosin to actin. J Biol Chem 261: 16155-16160, 1986.
31. Leopold PL, Kreitzer G, Miyazawa N, Rempel S, Pfister KK, Rodriguez-Boulan E, and Crystal RG. Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis. Hum Gene Ther 11: 151-165, 2000.
32. Li E, Stupack D, Bokoch GM, and Nemerow GR. Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases. J Virol 72: 8806-8812, 1998.
33. Lo C, Keese C, and Giaever I. Impedance analysis of MDCK cells measured by electric cell-substrate impedance sensing. Biophys J 69: 2800-2807, 1995.
34. Marston SB and Redwood CS. The molecular anatomy of caldesmon. Biochem J 279: 1-16, 1991.
35. Matsumura F and Yamashiro S. Caldesmon. Curr Opin Cell Biol 5: 70-76, 1993.
36. Montesano R and Orci L. Transforming growth factor β stimulates collagen-matrix contraction by fibroblasts: implication for wound healing. Proc Natl Acad Sci USA 85: 4894-4897, 1988.
37. Moy A, Blackwell K, and Kamath A. Differential effects of histamine and thrombin on endothelial barrier function through actin-myosin tension. Am J Physiol Heart Circ Physiol 282: H21-H29, 2002.
38. 20-dependent tension development. Am J Physiol Lung Cell Mol Physiol 274: L1024-L1029, 1998.
39. Moy A, Scott B, Shasby S, and Shasby DM. The effect of histamine and cyclic adenosine monophosphate on myosin light chain phosphorylation in human umbilical vein endothelial cells. J Clin Invest 92: 1198-1206, 1993.
40. Moy AB, Van Engelenhoven J, Bodmer J, Kamath J, Keese C, Giaever I, Shasby S, and Shasby DM. Histamine and thrombin modulates endothelial focal adhesion through centripetal and centrifugal forces. J Clin Invest 97: 1020-1027, 1996.
41. Moy AB, Winter M, Kamath A, Blackwell K, Reyes G, Giaever I, Keese C, and Shasby DM. Histamine alters endothelial barrier function at cell-cell and cell-matrix sites. Am J Physiol Lung Cell Mol Physiol 278: L888-L898, 2000.
42. Pilcher BK, Levine NS, and Tomasek JJ. Thrombin promotion of isometric contraction in fibroblasts: its extracellular mechanism of action. Plast Reconstr Surg 96: 1188-1195, 1995.
43. Schuppan D, Atkinson J, Ruehl M, and Riecken EO. Alcohol and liver fibrosis-pathobiochemistry and treatment. Zeit Gastroenterologie 33: 546-550, 1995.
44. 32P-labeled arterial smooth muscle. Am J Physiol Cell Physiol 259: C631-C639, 1990.
45. Staufenbiel M, Epple P, and Deppert W. Progressive reorganization of the host cell cytoskeleton during adenovirus infection. J Virol 60: 1186-1191, 1986.
46. Surgucheva I and Bryan J. Over-expression of smooth muscle caldesmon in mouse fibroblasts. Cell Molli Cytoskeleton 32: 233-243, 1995.
47. r caldesmon by protein kinase C modulates the regulatory function of this protein on the interaction between actin and myosin. Eur J Biochem 188: 495-500, 1990.
48. Van Loo ND, Fortunati E, Ehlert E, Rabelink M, Grosveld F, and Scholte BJ. Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids. J Virol 75: 961-970, 2001.
49. Warren KS, Shutt DC, McDermott JP, Lin JL, Soll DR, and Lin JJ. Overexpression of microfilament-stabilizing human caldesmon fragment, CaD39, affects cell attachment, spreading, and cytokinesis. Cell Motil Cytoskeleton 34: 215-229, 1996.
50. Yamashiro-Matsumura S and Matsumura F. Characterization of 83-kilodalton nonmuscle caldesmon from cultured rat cells: stimulation of actin binding of nonmuscle tropomyosin and periodic localization along microfilaments like tropomyosin. J Cell Biol 106: 1973-1983, 1988.