메뉴 건너뛰기




Volumn 58, Issue 8, 2004, Pages 801-806

Vardenafil: A new oral treatment for erectile dysfunction

Author keywords

Erectile dysfunction; Phosphodiesterase type 5 inhibitor; Vardenafil

Indexed keywords

ALFUZOSIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALUMINUM HYDROXIDE; ANTIHYPERTENSIVE AGENT; CARDIOVASCULAR AGENT; CIMETIDINE; CYCLIC GMP; ERYTHROMYCIN; KETOCONAZOLE; PHOSPHODIESTERASE V INHIBITOR; PLACEBO; RANITIDINE; SILDENAFIL; TADALAFIL; TAMSULOSIN; VARDENAFIL;

EID: 4544340338     PISSN: 13685031     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1368-5031.2004.00213.x     Document Type: Article
Times cited : (7)

References (20)
  • 1
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994; 151: 54-61.
    • (1994) J. Urol. , vol.151 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 2
    • 0032810944 scopus 로고    scopus 로고
    • The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences
    • Aytac IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999; 84: 50-6.
    • (1999) BJU Int. , vol.84 , pp. 50-56
    • Aytac, I.A.1    McKinlay, J.B.2    Krane, R.J.3
  • 3
    • 2542438558 scopus 로고    scopus 로고
    • The multinational men's attitudes to life events and sexuality (MALES) Study: I. Prevalence of erectile dysfunction and related health concerns in the general population
    • Rosen RC, Fisher WA, Eardley I, Niederberger C, Nadel A, Sand M. The multinational men's attitudes to life events and sexuality (MALES) Study: I. Prevalence of erectile dysfunction and related health concerns in the general population. Curr Med Res Opin. 2004; 20 (5): 607-17.
    • (2004) Curr. Med. Res. Opin. , vol.20 , Issue.5 , pp. 607-617
    • Rosen, R.C.1    Fisher, W.A.2    Eardley, I.3    Niederberger, C.4    Nadel, A.5    Sand, M.6
  • 4
    • 0035157613 scopus 로고    scopus 로고
    • The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil
    • Saenz de Tejada I, Angulo J, Cuevas P et al. The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Int J Impot Res 2001; 13: 282-90.
    • (2001) Int. J. Impot. Res. , vol.13 , pp. 282-290
    • Saenz de Tejada, I.1    Angulo, J.2    Cuevas, P.3
  • 5
    • 0035258442 scopus 로고    scopus 로고
    • Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients: A RigiScan and pharmacokinetic study
    • Koltz T, Sachse R, Heidrich A et al. Vardenafil increases penile rigidity and tumescence in erectile dysfunction patients: a RigiScan and pharmacokinetic study. World J Urol 2001; 19 (1): 32-9.
    • (2001) World J. Urol. , vol.19 , Issue.1 , pp. 32-39
    • Koltz, T.1    Sachse, R.2    Heidrich, A.3
  • 6
    • 0037370684 scopus 로고    scopus 로고
    • Effect of high-fat breakfast and moderate-fat evening meal on the pharmacokinetics of vardenafil, an oral phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction
    • Rajagopalan P, Mazzu A, Xia C, Dawkins R, Sundaresan P. Effect of high-fat breakfast and moderate-fat evening meal on the pharmacokinetics of vardenafil, an oral phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction. J Clin Pharmacol 2003; 43 (3): 260-7.
    • (2003) J. Clin. Pharmacol. , vol.43 , Issue.3 , pp. 260-267
    • Rajagopalan, P.1    Mazzu, A.2    Xia, C.3    Dawkins, R.4    Sundaresan, P.5
  • 7
    • 0036121963 scopus 로고    scopus 로고
    • Pharmacokinetics of sildenafil citrate after single oral doses in healthy male subjects: Absolute bioavailability, food effects and dose proportionality
    • Nichols DJ, Muirhead GJ, Harness JA. Pharmacokinetics of sildenafil citrate after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality. Br J Clin Pharmacol 2002; 53 (Suppl. 1): 5S-12S.
    • (2002) Br. J. Clin. Pharmacol. , vol.53 , Issue.SUPPL. 1
    • Nichols, D.J.1    Muirhead, G.J.2    Harness, J.A.3
  • 8
    • 4544347733 scopus 로고    scopus 로고
    • Dose normalised pharmacokinetics of Tadalafil (IC351) administered as a single dose to healthy volunteers
    • [Abstract 120]
    • Patterson B, Bedding A, Jewell H, Payne C, Mitchell M. Dose normalised pharmacokinetics of Tadalafil (IC351) administered as a single dose to healthy volunteers. Int J Impot Res; 13 (Suppl. 4): [Abstract 120].
    • Int. J. Impot. Res. , vol.13 , Issue.SUPPL. 4
    • Patterson, B.1    Bedding, A.2    Jewell, H.3    Payne, C.4    Mitchell, M.5
  • 9
    • 0000674216 scopus 로고    scopus 로고
    • Effect of renal impairment on the single dose pharmacokinetics of vardenafil 20 mg, selective PDE5 inhibitor for the treatment of erectile dysfunction
    • Klotz T, Bauer RJ, Wensing G. Effect of renal impairment on the single dose pharmacokinetics of vardenafil 20 mg, selective PDE5 inhibitor for the treatment of erectile dysfunction. Pharmacotherapy 2002; 22: 418.
    • (2002) Pharmacotherapy , vol.22 , pp. 418
    • Klotz, T.1    Bauer, R.J.2    Wensing, G.3
  • 10
    • 0036868441 scopus 로고    scopus 로고
    • Vardenafil for treatment of men with erectile dysfunction: Efficacy and safety in a randomized, double-blind, placebo-controlled trial
    • Hellstrom WJ, Gittelman M, Karlin G et al. Vardenafil for treatment of men with erectile dysfunction: efficacy and safety in a randomized, double-blind, placebo-controlled trial. J Androl 2002; 23 (6): 763-71.
    • (2002) J. Androl. , vol.23 , Issue.6 , pp. 763-771
    • Hellstrom, W.J.1    Gittelman, M.2    Karlin, G.3
  • 11
    • 0034868820 scopus 로고    scopus 로고
    • The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: The first at-home clinical trial
    • Porst H, Rosen R, Padma-Nathan H et al. The efficacy and tolerability of vardenafil, a new, oral, selective phosphodiesterase type 5 inhibitor, in patients with erectile dysfunction: the first at-home clinical trial. Int J Impot Res 2001; 13 (4): 192-9.
    • (2001) Int. J. Impot. Res. , vol.13 , Issue.4 , pp. 192-199
    • Porst, H.1    Rosen, R.2    Padma-Nathan, H.3
  • 12
    • 4544321421 scopus 로고    scopus 로고
    • Efficacy of vardenafil in a flexible dose regimen: A placebo controlled trial
    • Hatzichristou D, Montorisi F, Taylor T. Efficacy of vardenafil in a flexible dose regimen: A placebo controlled trial. J Androl 2003; (Supplement): 48.
    • (2003) J. Androl. , Issue.SUPPL. , pp. 48
    • Hatzichristou, D.1    Montorisi, F.2    Taylor, T.3
  • 13
    • 4544288353 scopus 로고    scopus 로고
    • Vardenafil restores erectile function to normal range in men with erectile dysfunction
    • for the North American and European vardenafil study group. [in press]
    • Padma-Nathan H, Montorsi F, Giuliano F et al for the North American and European vardenafil study group. Vardenafil restores erectile function to normal range in men with erectile dysfunction. Urology [in press].
    • Urology
    • Padma-Nathan, H.1    Montorsi, F.2    Giuliano, F.3
  • 14
    • 0344215228 scopus 로고    scopus 로고
    • Reliable efficacy over time of vardenafil, a highly selective PDE5 inhibitor in men with erectile dysfunction: A retrospective analysis of two pivotal Phase III studies
    • [Abstract 98]
    • Montorsi F, Hellstrom WJG, Valiquette L, Eardley I, Homering M, Bandel TJ. Reliable efficacy over time of vardenafil, a highly selective PDE5 inhibitor in men with erectile dysfunction: A retrospective analysis of two pivotal Phase III studies. Prog Urol 2003; 13 (Suppl. 2): 31. [Abstract 98].
    • (2003) Prog. Urol. , vol.13 , Issue.SUPPL. 2 , pp. 31
    • Montorsi, F.1    Hellstrom, W.J.G.2    Valiquette, L.3    Eardley, I.4    Homering, M.5    Bandel, T.J.6
  • 15
    • 0345077466 scopus 로고    scopus 로고
    • Sustained efficacy and tolerability of vardenafil over two years in men with erectile dysfunction
    • [Abstract 100]
    • Stief C, Porst H, Saenz de Tejada I, Ulbrich E. Sustained efficacy and tolerability of vardenafil over two years in men with erectile dysfunction. Prog Urol 2003; 13 (Suppl. 2): 31. [Abstract 100].
    • (2003) Prog. Urol. , vol.13 , Issue.SUPPL. 2 , pp. 31
    • Stief, C.1    Porst, H.2    Saenz de Tejada, I.3    Ulbrich, E.4
  • 16
    • 0042405173 scopus 로고    scopus 로고
    • Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: A multicenter double-blind placebo-controlled fixed-dose study
    • Vardenafil. Diabetes Study Group
    • Goldstein I, Young JM, Fischer J, Bangerter K, Segerson T, Taylor T, Vardenafil Diabetes Study Group. Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study. Diabetes Care 2003; 26 (3): 777-83.
    • (2003) Diabetes Care , vol.26 , Issue.3 , pp. 777-783
    • Goldstein, I.1    Young, J.M.2    Fischer, J.3    Bangerter, K.4    Segerson, T.5    Taylor, T.6
  • 17
    • 0043194001 scopus 로고    scopus 로고
    • Safety and efficacy of vardenafil for the treatment of men with erectile dysfunction after radical retropubic prostatectomy
    • Brock G, Nehra A, Lipshultz LI et al. Safety and efficacy of vardenafil for the treatment of men with erectile dysfunction after radical retropubic prostatectomy. J Urol 2003; 170 (4 Part 1): 1278-83.
    • (2003) J. Urol. , vol.170 , Issue.4 PART 1 , pp. 1278-1283
    • Brock, G.1    Nehra, A.2    Lipshultz, L.I.3
  • 18
    • 4544247613 scopus 로고    scopus 로고
    • Earliest time of onset of erections with vardenafil determined in an at-home setting
    • Padma Nathan H, Kaufman J, Taylor T. Earliest time of onset of erections with vardenafil determined in an at-home setting. J Androl 2003; (Supplement): 48.
    • (2003) J. Androl. , Issue.SUPPL. , pp. 48
    • Padma Nathan, H.1    Kaufman, J.2    Taylor, T.3
  • 19
    • 0038767066 scopus 로고    scopus 로고
    • Cardiovascular safety of vardenafil a potent highly selective PDE5 inhibitor in patients with erectile dysfunction: An analysis of 5 placebo controlled trials
    • Kloner R, Mohan P, Norenberg C et al. Cardiovascular safety of vardenafil a potent highly selective PDE5 inhibitor in patients with erectile dysfunction: an analysis of 5 placebo controlled trials. Pharmacotherapy 2002; 22: 1371.
    • (2002) Pharmacotherapy , vol.22 , pp. 1371
    • Kloner, R.1    Mohan, P.2    Norenberg, C.3
  • 20
    • 0037021566 scopus 로고    scopus 로고
    • The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease
    • Thadani U, Smith W, Nash S et al. The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease. J Am Coll Cardiol 2002; 40 (11): 2006-12.
    • (2002) J. Am. Coll. Cardiol. , vol.40 , Issue.11 , pp. 2006-2012
    • Thadani, U.1    Smith, W.2    Nash, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.