Alterations in T-cell signal transduction molecules associated with recurrent spontaneous pregnancy loss

Journal of Reproductive Immunology

Volumn 63, Issue 2, 2004, Pages 137-154

  Taylor, Douglas D ^a   Gercel Taylor, Cicek ^a  

^a Departments of Obstetrics   (United States)

Author keywords

Apoptosis; Recurrent pregnancy loss; Recurrent spontaneous abortion; Signal transduction; T lymphocytes

Indexed keywords

CD3 ANTIGEN; INTERLEUKIN 2; JANUS KINASE; PROTEIN BAX; PROTEIN BCL 2; STAT5 PROTEIN;

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPONTANEOUS ABORTION; T LYMPHOCYTE; WESTERN BLOTTING;

ABORTION, HABITUAL; ADULT; ANTIGENS, CD3; APOPTOSIS; CELL LINE, TUMOR; CHROMATOGRAPHY, GEL; DNA-BINDING PROTEINS; EMBRYO LOSS; FEMALE; HUMANS; INTERLEUKIN-2; JANUS KINASE 3; MILK PROTEINS; PREGNANCY; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TRANS-ACTIVATORS;

EID: 4544328161     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2004.06.001     Document Type: Article

References (40)

1. E. Alberman The epidemiology of repeated abortion. R.W. Beard F. Sharp Early Pregnancy Loss: Mechanisms and Treatment 1988 Springer-Verlag New York 9 17
2. M.G. Baines, and R.L. Gendron Natural and experimental animal models of reproductive failure. G. Chaouat Immunology of Pregnancy 1993 CRC Press Boca Raton 173 203
3. M.D. Bates, S. Quenby, K. Takakuwa, P.M. Johnson, and G.S. Vince Aberrant cytokine production by peripheral blood mononuclear cells in recurrent pregnancy loss? Hum. Reprod. 17 2002 2439 2444
4. B.L. Bermas, and J.A. Hill Proliferative responses to recall antigens are associated with pregnancy outcome in women with a history of recurrent spontaneous abortion J. Clin. Invest. 100 1997 1330 1334
5. R. Brown, C. Clugston, P. Burns, A. Edlin, P. Vasey, B. Vojtesek, and S.B. Kaye Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines Int. J. Cancer 55 1993 678 684
6. G. Chaouat Innately moving away from the Th1/Th2 paradigm in pregnancy Clin. Exp. Immunol. 131 2003 393 395
7. G. Chaouat, S. Zourbas, S. Ostojic, G. Lappree-Delage, S. Dubanchet, N. Ledee, and J. Martal A brief review of recent data on some cytokine expressions at the materno-foetal interface which might challenge the classical Th1/Th2 dichotomy J. Reprod. Immunol. 53 2002 241 256
8. S.R. Choudhury, and L.A. Knapp Human reproductive failure I: Immunological factors Hum. Reprod. Update 7 2000 113 134
9. C.B. Coulam Epidemiology of recurrent spontaneous abortion Am. J. Reprod. Ummunol. 26 1991 23 27
10. D. Darmochwal-Kalarz, B. Leszcynska-Gorzelak, J. Rolinski, and J. Oleszezuk T helper 1- and T helper 2-type cytokine imbalance in pregnant women with preeclampsia Eur. J. Obstet. Gynecol. Reprod. Biol. 86 1999 165 170
11. J.A. DaSilva, and T.D. Spector The role of pregnancy in the course and etiology of rheumatoid arthritis Clin. Rheumatol. 11 1992 189 194
12. Z. Faust, G. Laskarin, D. Rukavina, and J. Szekeres-Bartho Progesterone-induced blocking factor inhibits degranulation of natural killer cells Am. J. Reprod. Immunol. 42 1999 71 75
13. J.A. Hill Sporadic and recurrent spontaneous abortion Curr. Probl. Obstet. Gynecol. Fertil. 17 1994 114 162
14. J.A. Hill, and B.C. Choi Immunodystrophism: Evidence for a novel alloimmune hypothesis for recurrent pregnancy loss involving Th1-type immunity to trophoblasts Semin. Reprod. Med. 18 2000 401 405
15. J.A. Hill, K. Polgar, B.L. Harlow, and D.J. Anderson Evidence of embryo and trophoblast-toxic cellular immune responses in women with recurrent spontaneous abortions Am. J. Obstet. Gynecol. 166 1992 1044 1052
16. E.N. Kersh, G.J. Kersh, and P.M. Allen Partially phosphorylated T cell receptor molecules can inhibit T cell activation J. Exp. Med. 190 1999 1627 1636
17. A. King, C. Hiby, and T. Verma Uterine NK cells and trophoblast HLA class I molecules et al. 37 1997 459 462
18. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature (London) 227 1970 680 685
19. C.J. Lockwood Prediction of pregnancy loss Lancet 355 2000 1292 1293
20. Y.W. Loke, and A. King Immunology of human implantation: an evolutionary perspective Hum. Reprod. 11 1996 283 286
21. B.J. Luft, and J.S. Remington Effect of pregnancy on augmentation of natural killer cell activity by Corynebacterium parvum and Toxoplasma gondii J. Immunol. 132 1984 2375 2380
22. M. Makhseed, R. Raghupathy, F. Azizieh, R. Farhat, N. Hassan, and A. Bandar Circulating cytokines and CD30 in normal human pregnancy and recurrent spontaneous abortions Hum. Reprod. 15 2000 2011 2017
23. I. Malan-Borel, S.M. Freire, A. Canellada, and R.A. Margni Effect of rat placental culture supernatants on cellular and humoral immune responses Am. J. Reprod. Immunol. 38 1997 366 373
24. S.C. Ng, A. Gilman-Sachs, P. Thaker, K.D. Beaman, A.E. Beer, and J. Kwak-Kim Expression of intracellular Th1 and Th2 cytokines in women with recurrentspontaneous abortion, implantation failures after IVF/ET or normal pregnancy Am. J. Reprod. Immunol. 48 2002 77 86
25. J.J. O'Shea, M. Gadina, and R.D. Schreiber Cytokine signaling in 2002: new surprises in the Jak/Stat pathway Cell 109 2002 S121 S131
26. K. Polgar, and J.A. Hill Identification of the white blood cell populations responsible for Th1 immunity to trophoblast and the timing of the response in women with recurrent pregnancy loss Gynecol. Obstet. Invest. 53 2002 59 64
27. L. Regan, P.R. Braude, and P.L. Trembath Influence of postreproductive performance on risk of spontaneous abortion Br. Med. J. 299 1989 541 545
28. J.G. Reid, N.A. Simpson, R.G. Walker, O. Economidou, J. Shillito, S.R. Duffy, J.J. Walker, and H.C. Gooi The carriage of pro-imflammatory cytokine gene polymorphisms in recurrent pregnancy loss Am. J. Reprod. Immunol. 45 2001 35 40
29. R.H. Reindollar Comtemporary issues for spontaneous abortion: does recurrent abortion exist? Obstet. Gynecol. Clin. 27 2000 541 554
30. S. Shimada, K. Iwabuchi, E.H. Kato, M. Morikawa, N. Sakuragi, K. Onoe, H. Minakami, and H. Yamada No difference in natural killer T cell population, but Th2/Tc2 predominance in peripheral blood of recurrent aborters Am. J. Reprod. Immunol. 50 2003 334 339
31. E.W. Shores, T. Tran, A. Grinberg, C.L. Sommers, H. Shen, and P.E. Love Role of the multiple T cell receptor (TCR)-ζ chain signaling motifs in selection of the T cell repertoire J. Exp. Med. 185 1997 893 900
32. E. Somigliana, P. Vigano, and M. Vignali Endometriosis and unexplained recurrent spontaneous abortion: pathological states resulting from aberrant modulation of natural killer cell function? Hum. Reprod. Update 5 1999 40 51
33. J. Szekeres-Bartho, G. Par, L. Szereday, C.Y. Smart, and I. Achatz Progesterone and non-specific immunologic mechanisms in pregnancy Am. J. Reprod. Immunol. 38 1997 176 182
34. J. Szekeres-Bartho, and T.G. Wegmann A progesterone-dependent immunomodulatory protein alters the Th1/Th2 balance J. Reprod. Immunol. 31 1996 81 95
35. L. Szereday, P. Spath, and J. Szekeres-Bartho Natural killer cell activity and cytokine production after in vitro immunoglobulin treatment of lymphocytes derived from pregnant women with or without risk for spontaneous abortion Am. J. Reprod. Immunol. 42 1999 282 287
36. L. Szereday, P. Varga, and J. Szekeres-Bartho Cytokine production by lymphocytes in pregnancy Am. J. Reprod. Immunol. 38 1997 418 422
37. D.D. Taylor, S.A. Sullivan, A.C. Eblen, and C. Gercel-Taylor Modulation of T-cell CD3-zeta chain expression during normal pregnancy J. Reprod. Immunol. 54 2002 15 31
38. N. Vassiliadou, R.F. Searle, and J.N. Bulmer Immunoregulatory activity of decidua in spontaneous early pregnancy loss Hum. Reprod. 14 1999 2252 2256
39. T.G. Wegmann, H. Lin, L. Guilbert, and T.R. Mosmann Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol. Today 14 1993 353 356
40. P.W. Whitecar, K.A. Boggess, M.J. McMahon, J.M. Thorp, and D.D. Taylor Altered expression of TcR/CD3ζ induced by sera from women with preeclampsia Am. J. Obstet. Gynecol. 185 2001 812 881